HOME >> MEDICINE >> NEWS
Study: Carbon dioxide may find new use in producing medical implants

ned.

The engineers' early tests with a protein solution suggest that supercritical CO2 may leave medicines intact.

They applied a coating of the protein solution onto dime-sized plastic disks with a cotton swab, and placed the disks in a glass tank, which they then filled with supercritical CO2. The proteins contained a fluorescent biomarker, so the researchers were able to track how well the proteins penetrated the plastic by examining cross-sections of the material under a microscope in ultraviolet light.

The microscope showed that the proteins survived the embedding process, and formed a layer 30 micrometers, or millionths of a meter, beneath the surface of the plastic.

Although the plastic -- polymethylmethacrylate, or PMMA -- was undamaged by the procedure, the interior of the disks foamed up into a Swiss cheese-like texture, with voids opening inside. The faster the engineers turned off the high-pressure CO2, the foamier the material became. Lowering the pressure slowly had the opposite effect.

Tomasko envisions that such voids within an implant could come in handy for holding extra quantities of a drug for long-term therapy.

Today, medical implants are used for mechanical support where tissue or bone has been removed. The researchers' vision is to "piggyback" drug delivery onto this mechanical function. The implant may be impregnated with drugs to prevent inflammation or infection following surgery. Or, in cases where a patient has had bone surgically removed as part of a treatment for cancer, doctors may also need to dispense anti-tumor agents from the implant for a longer period, Tomasko explained.

He's been working with David Powell, clinical assistant professor of otolaryngology, to investigate the potential use of such implants for patients who've had facial surgery.

Since completing their initial study, the engineers have begun using a porous glass disk to dispense protein solution onto t
'"/>

Contact: David Tomasko
Tomasko.1@osu.edu
614-292-4249
Ohio State University
23-Mar-2004


Page: 1 2 3

Related medicine news :

1. Study: Two brain systems regulate how we call for help
2. Study: Eye contact triggers threat signals in autistic childrens brains
3. Study: Young adults can be motivated to eat fruits, veggies
4. Study: Physical activity in middle age cuts risk of early death
5. Study: Brain battles itself over short-term rewards, long-term goals
6. Study: Dementia often undiagnosed in clinical settings
7. Study: Too few doctors ask teens about smoking
8. Study: Low-carb diet more effective than low-fat diet
9. Study: Many men take dietary supplements to prevent prostate cancer
10. Study: Height loss screen ultimately could reduce hip fractures
11. Study: New neurons can get out of spinal cord

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Study Carbon dioxide may find new use producing medical implants

(Date:5/24/2015)... 2015 The federal court overseeing ... has scheduled its next monthly Case Management Conference ... According to court documents filed in the U.S. ... will be convened on June 2, 2015, at ... Liability Litigation - MDL No. 2545) , “Our ...
(Date:5/24/2015)... May 24, 2015 ... CEO - The students were ... at the fourth annual A Day ... at Geneva National in Lake Geneva. ...     -Badger High School,         Jonathan Alfonso,         Bridget ...
(Date:5/23/2015)... May 23, 2015 Dr. David Benvenuti, an ... just posted a new article to his website ... Dr Benvenuti explained in the fascinating blog, he ... in their earlobes. , Known as “gauging,” the technique involves ... which Dr. Benvenuti said will eventually stretch the holes out ...
(Date:5/23/2015)... Manufacturers are now required to produce water heaters ... Experts in the field agree that the regulation is aimed ... score is what miles per gallon is to your car. ... the minimum HSPF score has been raised to 8.2, technology ... north of 12. Indeed, the regulation was welcomed by environmentalist, ...
(Date:5/23/2015)... May 23, 2015 Injury lawyer Steven H. ... been passed by the Maryland legislature but which has not ... General Assembly passed HB 449 with overwhelming bipartisan ... not signed it into law. This bill ensures that fracking ... growing that demonstrates the danger of fracking to our water ...
Breaking Medicine News(10 mins):Health News:Testosterone Lawsuit Attorneys at Bernstein Liebhard LLP Look Ahead to June Conference in Federal Multidistrict Litigation 2Health News:Testosterone Lawsuit Attorneys at Bernstein Liebhard LLP Look Ahead to June Conference in Federal Multidistrict Litigation 3Health News:Mercy Foundation Honors 16 Students for Making a Difference - Mercy Health System Javon Bea 2Health News:Dr. Benvenuti, a Plastic Surgeon in Newport Beach, CA, Posts New Article about Repairing Ear Gauges 2Health News:Parker & Sons Welcomes the Department of Energy’s Water Heater Regulation 2Health News:Baltimore Attorney Urges Governor Hogan to Sign the Fracking Moratorium Bill 2Health News:Baltimore Attorney Urges Governor Hogan to Sign the Fracking Moratorium Bill 3
(Date:5/21/2015)... DUBLIN , May 21, 2015 /PRNewswire/ ... http://www.researchandmarkets.com/research/5x7nlz/arthroscopy ) has announced the addition of ... report to their offering. ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ... to analyze and size the world market ... players and identifies trends impacting the market ...
(Date:5/21/2015)... , May 21, 2015  (MUSE Booth # ... Health Record (EHR) is invaluable in any hospital ... are now a requirement and mainstream in healthcare, ... into the EHR is gaining traction in MEDITECH ... Holmes, RN, Site Project Manager & Clinical Analyst ...
(Date:5/21/2015)... England , May 21, 2015 ... Bekämpfung von Arzneimittelfälschungen - Zwecks Leistungsvergleich ... Arzneimittelprüfdienstes wird auf EG-Mitgliedstaaten verwiesen, in ... betrieben werden.  Wählen Sie ein Aegate-Land: ... der Richtlinie zur Bekämpfung von Arzneimittelfälschungen ...
Breaking Medicine Technology:Analysing Arthroscopy Devices Markets Worldwide 2014-2020 2Analysing Arthroscopy Devices Markets Worldwide 2014-2020 3Hospital Streamlines ICU Efficiency with Timely Data Integration 2Hospital Streamlines ICU Efficiency with Timely Data Integration 3EU-Arzneimittel-Richtlinie für gefälschte Medikamente; Aegate-Zusammenfassung als reale Bewertung aus Belgien 2EU-Arzneimittel-Richtlinie für gefälschte Medikamente; Aegate-Zusammenfassung als reale Bewertung aus Belgien 3
Cached News: