HOME >> MEDICINE >> NEWS
Study Confirms Safety Of Common Heart Drug

CHAPEL HILL, N.C. -- A new study headed by researchers at the University of North Carolina at Chapel Hill confirms the safety of digoxin, one of the oldest and most frequently prescribed medicines and the most common digitalis drug for heart failure.

The study's findings clearly demonstrate that digoxin, when taken at low doses and with blood concentrations tailored to individual patients, is far less toxic than previously reported with higher doses, according to senior study author Dr. J. Herbert Patterson, associate professor of pharmacy and research associate professor of medicine at UNC-CH School of Medicine.

A report of the study appears in the December 7-21 issue of the Archives of Internal Medicine, a publication of the American Medical Association.

"We use lower doses and lower serum concentrations now and have better knowledge of the drug in general, including its interactions with other drugs. That's why we don't see as much toxicity anymore," Patterson says. "In our prospective study at five hospitals here in North Carolina, the overall incidence of toxicity was 4.1 percent, which is consistent with a recent retrospective review of hospital charts of heart failure patients in a large urban hospital."

"Over the years physicians, pharmacists and nurses have worked together and learned a lot more about the drug so we can tailor dosing more specifically toward a particular patient," says study lead-author Dr. Kristin M. Williamson, adjunct assistant professor at UNC's School of Pharmacy. "And what we've shown in our study is that compared with 20 or 30 years ago, the frequency of digoxin toxicity has decreased and is not as much of an issue anymore."

The three-month study also showed that monitoring for digoxin blood concentrations in hospitalized patients often occurs too soon after they take the drug. In nearly 16 percent of the patients studied, serum digoxin concentrations were sampled six hours or less after a dose was give
'"/>

Contact: Lynn Wooten
lwooten.est1@mail.unch.unc.edu
919-966-6046
University of North Carolina at Chapel Hill
9-Dec-1998


Page: 1 2 3

Related medicine news :

1. Study of energy and health in Africa focuses spotlight on charcoal and forest management
2. Study shows promise in identifying kidney failure
3. Study shows patch therapy may be as effective as oral medications
4. Study shows soy is well accepted in school lunches
5. Study finds that coordinating care of chronically ill patients does not increase liability
6. Study provides new estimates of the causes of child mortality worldwide
7. Study finds factors linked to substance use disorder relapse among health care professionals
8. Study finds majority of women willing to accept cervical cancer vaccine for self and children
9. Study shows use of budesonide reduced the risk of asthma related events by 40% in children
10. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
11. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/18/2019)... ... , ... A new study by BestPlaces looks at ten indicators to produce the first ranking ... so other related rights vary widely across the 50 states. , Ten topics ... orientation) , Employment , Education , Gender Marker Updates ...
(Date:9/17/2019)... ... September 17, 2019 , ... ... Europe and the 21st Century Cures Act in the US, Nocimed has been ... pain management. Using images from existing MRI equipment to perform MR spectroscopy, ...
(Date:9/17/2019)... ... 17, 2019 , ... What if a drug that sits ... patients? In companion presentations at the American Society for Therapeutic Radiation Oncology (ASTRO) ... evidence that low-dose aspirin and other anti-inflammatories may improve survival in patients undergoing ...
(Date:9/17/2019)... ... September 17, 2019 , ... ... pleased to announce the release of the third edition of The Gift of ... guide for patients, caregivers and families to navigate the clinical research process. The ...
(Date:9/12/2019)... COLUMBUS, Ohio (PRWEB) , ... September 12, 2019 ... ... recognized on both a local and national scale in two recent and well-renowned ... the country’s fastest-growing privately held businesses for the 2019 year. , Dr. ...
Breaking Medicine News(10 mins):
(Date:9/14/2019)... VAN WERT, Ohio (PRWEB) , ... September 13, 2019 , ... ... Tim Hutchens for his many years of service and wish him well on his ... Texas, New Mexico, Oklahoma, and Arkansas to contact them direct for inquires related to ...
(Date:9/14/2019)... ... 2019 , ... CME4Life, a leading provider of physician assistant ... at a world record “Longest Medical Lecture” on November 16, 2019. The lecture ... CME credits in 30 consecutive hours. ?The conference will take place at The ...
(Date:9/12/2019)... ... September 12, 2019 , ... iPatientCare, ... integrated practice management, and patient engagement solutions, announced today the participation of ... Conference (NUCON) 2019 . The annual conference features informative sessions about upcoming ...
Breaking Medicine Technology:
Cached News: