Study Leads To New Standard Of Care For Treating Unstable Angina: Heart-Attack,,Risk Reduced By 47% With Use Of Tirofiban

A major international study by cardiologists has shown that the addition of tirofiban into the medical management of patients with unstable angina reduces their risk of death by as much as 47%. Unstable angina is currently the leading cause of admissions to coronary care units, accounting for more than 1.4 million hospitalizations per year in the United States. Tirofiban, a member of a new class of anti-platelet inhibitors, proved so effective in decreasing the incidence of post-angina heart-attacks that the researchers recommended its use as part of a new therapeutic standard of care. The researchers' study and clinical recommendation will be published in the May 21 issue of The New England Journal of Medicine.

Unstable angina is a life-threatening cardiac condition that occurs when bloodflow to the heart muscle is disrupted or impaired. In most cases, the pain of angina is associated with the rupturing of large cholesterol plaques that have built-up, over time, near the outer walls of the heart chamber. "At the present time, we treat this condition with a combination of heparin and aspirin because both of those drugs have unique properties that encourage the dissolution of plaques," explains Howard Herrmann, MD, associate professor of medicine at the University of Pennsylvania Medical Center -- one of the 72 participating trial sites. "Our study showed that the intravenous introduction of tirofiban into the standard treatment protocol provides additional benefit to patients because tirofiban helps prevent the development of plaque deposits by blocking the aggregation of platelets -- which is a precursor to clot development."

In their two-year investigation of 1,915 patients with unstable angina or non-Q-wave myocardial infarction (which represents the middle ground, clinically speaking, between angina and a full-blown heart attack), the researchers tested the effectiveness of tirofiban in addition to heparin and aspirin [PRISM-PLUS]

Contact: Rebecca Harmon
University of Pennsylvania School of Medicine

Page: 1 2

Related medicine news :

1. Study of energy and health in Africa focuses spotlight on charcoal and forest management
2. Study shows promise in identifying kidney failure
3. Study shows patch therapy may be as effective as oral medications
4. Study shows soy is well accepted in school lunches
5. Study finds that coordinating care of chronically ill patients does not increase liability
6. Study provides new estimates of the causes of child mortality worldwide
7. Study finds factors linked to substance use disorder relapse among health care professionals
8. Study finds majority of women willing to accept cervical cancer vaccine for self and children
9. Study shows use of budesonide reduced the risk of asthma related events by 40% in children
10. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
11. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women

Post Your Comments:

(Date:10/13/2017)... ... ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many kids this ... by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids excited about ... ages; it is a non-competitive, non-timed event, which is all about having fun and ...
(Date:10/13/2017)... ... , ... “America On The Brink”: the Christian history of the United States ... creation of published author, William Nowers. Captain Nowers and his wife, Millie, have ... thirty years in the Navy. Following his career as a naval aviator and ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ... introduction of an innovative new design of the shoulder pad. The shoulder pad ... comfort while controlling your pain while using cold therapy. By utilizing ice and water ...
(Date:10/12/2017)... ... ... HMP , a leader in healthcare events and education, today announced that ... ‘Best B-to-B Healthcare Website.’ Winners were announced during the Eddie & Ozzie Awards luncheon ... editorial and design excellence across a range of sectors. This year’s program included the ...
(Date:10/12/2017)... ... 2017 , ... In the United States, single-family home owners ... New York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and California—the average is $7,000 ... property-tax rates, which contributes to the relatively lower cost of living in places ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... 2017  According to the Centers for Disease Control and Prevention (CDC), ... PhysicianOne Urgent Care is helping communities across Massachusetts , ... by offering no-cost* flu shots through the end of the month. ... insurance regulations. ... get a flu shot is by the end of October, according to ...
(Date:10/2/2017)... , Oct. 2, 2017  AllianceRx Walgreens Prime, the ... by Walgreens and pharmacy benefit manager Prime Therapeutics LLC ... brand, which included the unveiling of new signage at ... as well as at a few other company-owned facilities ... brand to patients, some of whom will begin to ...
(Date:9/28/2017)... -- Cohen Veterans Bioscience and Early Signal Foundation announce ... home sensors for real-time monitoring of patients with trauma-related ... organization focused on disruptive health solutions for rare disorders ... to record and integrate behavioral, cognitive, physiological and contextual ... ...
Breaking Medicine Technology:
Cached News: