HOME >> MEDICINE >> NEWS
Study Leads To New Standard Of Care For Treating Unstable Angina: Heart-Attack,,Risk Reduced By 47% With Use Of Tirofiban

A major international study by cardiologists has shown that the addition of tirofiban into the medical management of patients with unstable angina reduces their risk of death by as much as 47%. Unstable angina is currently the leading cause of admissions to coronary care units, accounting for more than 1.4 million hospitalizations per year in the United States. Tirofiban, a member of a new class of anti-platelet inhibitors, proved so effective in decreasing the incidence of post-angina heart-attacks that the researchers recommended its use as part of a new therapeutic standard of care. The researchers' study and clinical recommendation will be published in the May 21 issue of The New England Journal of Medicine.

Unstable angina is a life-threatening cardiac condition that occurs when bloodflow to the heart muscle is disrupted or impaired. In most cases, the pain of angina is associated with the rupturing of large cholesterol plaques that have built-up, over time, near the outer walls of the heart chamber. "At the present time, we treat this condition with a combination of heparin and aspirin because both of those drugs have unique properties that encourage the dissolution of plaques," explains Howard Herrmann, MD, associate professor of medicine at the University of Pennsylvania Medical Center -- one of the 72 participating trial sites. "Our study showed that the intravenous introduction of tirofiban into the standard treatment protocol provides additional benefit to patients because tirofiban helps prevent the development of plaque deposits by blocking the aggregation of platelets -- which is a precursor to clot development."

In their two-year investigation of 1,915 patients with unstable angina or non-Q-wave myocardial infarction (which represents the middle ground, clinically speaking, between angina and a full-blown heart attack), the researchers tested the effectiveness of tirofiban in addition to heparin and aspirin [PRISM-PLUS]
'"/>

Contact: Rebecca Harmon
harmonr@mail.med.upenn.edu
215-349-5660
University of Pennsylvania School of Medicine
21-May-1998


Page: 1 2

Related medicine news :

1. Study of energy and health in Africa focuses spotlight on charcoal and forest management
2. Study shows promise in identifying kidney failure
3. Study shows patch therapy may be as effective as oral medications
4. Study shows soy is well accepted in school lunches
5. Study finds that coordinating care of chronically ill patients does not increase liability
6. Study provides new estimates of the causes of child mortality worldwide
7. Study finds factors linked to substance use disorder relapse among health care professionals
8. Study finds majority of women willing to accept cervical cancer vaccine for self and children
9. Study shows use of budesonide reduced the risk of asthma related events by 40% in children
10. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
11. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/22/2018)... ... ... Liz Dudek, Director of Health Care Affairs for global law firm Greenberg ... Florida Assisted Living Association (FALA) at 10:00 a.m. at Tessera of Brandon located at ... of the success of the first five years of Florida’s Statewide Medicaid Managed Care ...
(Date:9/22/2018)... ... 22, 2018 , ... The Lymphoma Research Foundation (LRF) – ... serving the lymphoma community through a comprehensive series of education programs, outreach initiatives ... cycling event held each year during Blood Cancer Awareness Month. , This year’s ...
(Date:9/13/2018)... ... ... The Kelly Foundation awarded $83,000 to Saint John’s Program ... children experiencing homelessness in the Sacramento region. The donation will go towards the ... Saint John’s open after the County of Sacramento decided not to renew its 15-year ...
(Date:9/12/2018)... (PRWEB) , ... September 13, 2018 , ... Donaldson Plastic ... companies, as well as Columbus Business First's Fast 50 list of central Ohio's fastest ... with a 3-year growth rate of 81 percent. It is the only medical practice ...
(Date:9/7/2018)... ... 07, 2018 , ... The Ramsey Keller Memorial , a non-profit organization ... moms who are living without a child. “ The Retreat ” is designed to ... and 28 at Fairmont Hot Springs Resort near Butte, Montana. The registration ...
Breaking Medicine News(10 mins):
(Date:9/12/2018)... ... September 12, 2018 , ... Patient experience and population ... of its Population Engage patient experience suite. Express Surveys are short, streamlined ... provider organization a wealth of strategic and tactical knowledge in order to take ...
(Date:9/12/2018)... ... September 13, 2018 , ... Safety Reporting in ... 2018 — 1:30 p.m. – 3:00 p.m. ET, http://info.fdanews.com/safety-reporting-in-global-clinical-trials , Clinical ... much as fifty percent. , This can be due to a lack ...
(Date:9/7/2018)... ... ... This year, the California Society of Plastic Surgeons (CSPS) awarded Dr. Terry ... Seven-Year Clinical Trial Results at the 68th CSPS Annual Meeting. Dr. Zimmerman has ... of Plastic Surgeons) meeting in Chicago this fall. , “I am honored to receive ...
Breaking Medicine Technology:
Cached News: