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Study Leads To New Standard Of Care For Treating Unstable Angina: Heart-Attack,,Risk Reduced By 47% With Use Of Tirofiban

. They found that tirofiban -- in combination with heparin/aspirin --resulted in a 47% risk-reduction for heart attack within the first week of treatment, and a 30% risk-reduction at thirty days. "These numbers demonstrate very clearly the effectiveness of including tirofiban in the standard of care for treating patients with angina," notes Herrmann, who served as principal investigator for the Penn portion of the world-wide study.

On the basis of the study results, tirofiban has received approval from the Food and Drug Administration (FDA) for the treatment of unstable angina. The drug is manufactured by Merck under the trade name of aggrastat.


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Contact: Rebecca Harmon
harmonr@mail.med.upenn.edu
215-349-5660
University of Pennsylvania School of Medicine
21-May-1998


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