Study Ties Cerebral Palsy To Inflammation And Blood-Clotting Abn...( f cytokines and coagulationfactors may...),Health

f cytokines and coagulation factors may act differently than single factors alone, future research should focus on an array of these substances in the blood, rather than on one substance at a time, they say. Researchers also need to clarify what concentrations of different substances are normal for infants of different ages and to examine how levels of these factors might become elevated and lead to brain damage.

The NINDS, one of the National Institutes of Health located in Bethesda, Maryland, is the nation's leading supporter of research on the brain and nervous system and a lead agency for the Congressionally designated Decade of the Brain. The California Birth Defects Monitoring Program, a public health program devoted to finding causes of birth defects, is funded by the California Department of Health Services and jointly operated with the March of Dimes Birth Defects Foundation.

(1) Nelson, K.B.; Dambrosia, J.M.; Grether, J.K., and Phillips, T.M. "Neonatal Cytokines and Coagulation Factors in Children with Cerebral Palsy." Annals of Neurology, October 1998, Vol. 44., No. 4, pp. 665-667.

(2) Grether, J.K., and Nelson, K.B. "Maternal Infection and Cerebral Palsy in Infants of Normal Birth Weight." Journal of the American Medical Association, July 16, 1997, Vol. 278, No. 3, pp. 207-211.

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Contact: Natalie Larsen
(301) 496-5751
NIH/National Institute of Neurological Disorders and Stroke
1-Oct-1998

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