Study demonstrates improved survival in women with metastatic breast cancer

Copenhagen, Denmark September 24, 2003 Today at the European Cancer Conference (ECCO) annual meeting, results from a randomized, Phase III study were presented which demonstrated that women with metastatic breast cancer who were treated with Taxotere (docetaxel) Injection Concentrate had a statistically significant improvement in overall survival and time to disease progression compared to those who were treated with paclitaxel. Both these agents are in a class of drugs knows as taxanes that are used extensively to treat women with metastatic breast cancer.

The multi-center study included 449 women who were randomized to either Taxotere 100mg/m2 (1 hour infusion) or paclitaxel 175 mg/m2 (3 hour infusion) every three weeks. Treatment was continued until progression of disease, unmanageable toxicity or intercurrent illness occurred, or until the patient decided to terminate treatment for any other reason. Eligibility criteria included: bi-dimensionally measurable metastatic breast cancer, having failed either one prior anthracycline-based regimen as first-line therapy for metastatic breast cancer or disease progression during or within 12 months of completing anthracycline-based adjuvant or neoadjuvant chemotherapy.

"While Taxotere is already the most widely used chemotherapy agent in the treatment of women with metastatic breast cancer, this trial offers more hope to women with breast cancer and has significance in treatment decisions," said Peter Ravdin, M.D., Ph.D., an Associate Professor of Oncology at the University of Texas Health Science Center at San Antonio and Principal Investigator of the study. "Taxanes have been proven to be a leading class of agents across a wide range of cancers. This trial is an important comparison of the taxanes that may influence future research and treatment strategies."

The primary endpoint of this study was the rate of overall response (tumor shrinkage). The secondary endpoints included time to

Contact: Arleen Goldenberg
Cohn & Wolfe

Page: 1 2

Related medicine news :

1. Study of energy and health in Africa focuses spotlight on charcoal and forest management
2. Study shows promise in identifying kidney failure
3. Study shows patch therapy may be as effective as oral medications
4. Study shows soy is well accepted in school lunches
5. Study finds that coordinating care of chronically ill patients does not increase liability
6. Study provides new estimates of the causes of child mortality worldwide
7. Study finds factors linked to substance use disorder relapse among health care professionals
8. Study finds majority of women willing to accept cervical cancer vaccine for self and children
9. Study shows use of budesonide reduced the risk of asthma related events by 40% in children
10. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
11. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women

Post Your Comments:

(Date:5/22/2019)... ... May 22, 2019 , ... With record-breaking starting positions, three drivers from Ed ... Jones have qualified their Chevrolets for the team’s entry in the 103rd running ... IndyCar Series qualifying run, Pigot was sitting in pole position in his No. 21 ...
(Date:5/22/2019)... ... 22, 2019 , ... In the second quarter of 2019, ... structure that aligns both the east and west coast operations under a single ... west coast operations center, and Global Medical Imaging has relocated nearby to the ...
(Date:5/22/2019)... ... May 22, 2019 , ... Today, The Fenway Institute ... cervical cancer among transmasculine patients who were assigned a female sex at birth ... Although over 90 percent of such patients retain female reproductive organs, they are ...
(Date:5/22/2019)... NEW YORK (PRWEB) , ... May 22, 2019 ... ... recently published paper by Walmart and Covera Health studying the economic impact of ... for Walmart, the key issue is that the interpretations of the diagnostic imaging ...
(Date:5/22/2019)... ... ... There are over 2.3 million people with multiple sclerosis (MS) worldwide; in the US ... are diagnosed each year. The need for precision medicine-based approaches to diagnose and treat ... manage due to a lack of identified biomarkers that predict disease onset, progression and ...
Breaking Medicine News(10 mins):
(Date:5/23/2019)... ... May 23, 2019 , ... NATIONAL OFFICE – BKD CPAs ... national industry partner (NIP) of the health care practice. Former NIP Eddie Marmouget will ... to be chosen to lead our national health care practice and work more closely ...
(Date:5/22/2019)... ... May 22, 2019 , ... ... pleased to announce the successful closing of the $22,375,000 Series 2019 for Trevecca ... Educational Facilities Board of the Metropolitan Government of Nashville and Davidson County, Tennessee. ...
(Date:5/22/2019)... Ala. (PRWEB) , ... May 22, 2019 , ... ... Modern Healthcare magazine ranked Robins & Morton third among the top general contractors ... $952,929,266 in revenue and more than 3.5 million square feet in completed healthcare ...
Breaking Medicine Technology:
Cached News: