A recent trial, published in the Journal of Cardiovascular Electrophysiology, shows that women with abnormal heart rhythms benefit from implantable cardioverter defibrillators (ICDs) as much as men, stressing the importance of including females in future research. Previous studies have raised the concern of possible gender bias, in favor of men, in the evaluation and treatment of heart disease.
The Multicenter UnSustained Tachycardia Trial (MUSTT) studied the influence of gender in 2,202 patients with coronary artery disease and an abnormal heart pumping function across 85 clinical sites. Among the patients studied, characteristics, treatment and outcome were analyzed. The most significant differences noted were that the women in the trial were older, more likely to have had a heart attack within six months of enrollment, more likely to have experienced angina within six weeks prior to enrollment, and less likely to have atrial fibrillation than the men. An overall benefit from the ICD was observed (45% in men and 53% in women) with no significant influence related to gender.
"This [study] has implications for the development of future trials and stresses the importance of making every effort to include women," said Dr. Andrea Russo, lead investigator of MUSTT. "As cardiovascular disease is the leading cause of death in both men and women, this also emphasizes the importance of ensuring that women have access to the ICD, in addition to any other life-saving cardiovascular therapies."
According to the study, "it has been suggested that there is gender bias in referral for invasive treatment and this may have an impact on outcome." However, reasons for the differences may be a matter of age, severity of coronary disease, and other risk factors.
Page: 1 Related medicine news :1
Contact: Sharon Agsalda
Blackwell Publishing Ltd.
. Study of energy and health in Africa focuses spotlight on charcoal and forest management2
. Study shows promise in identifying kidney failure3
. Study shows patch therapy may be as effective as oral medications4
. Study shows soy is well accepted in school lunches5
. Study finds that coordinating care of chronically ill patients does not increase liability6
. Study provides new estimates of the causes of child mortality worldwide7
. Study finds factors linked to substance use disorder relapse among health care professionals8
. Study finds majority of women willing to accept cervical cancer vaccine for self and children9
. Study shows use of budesonide reduced the risk of asthma related events by 40% in children10
. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased11
. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women