HOME >> MEDICINE >> NEWS
Study examines limited-field radiation for early breast cancer

Data from a five-year study suggests that limited-field radiation therapy (radiation directed at the tumor site) may be as effective as whole-breast radiation therapy in preventing breast cancer recurrence in women treated with breast-conserving surgery. The study appears in the August 20 issue of the Journal of the National Cancer Institute.

Whole-breast radiation therapy is part of standard treatment for women with early-stage breast cancer who have undergone breast-conserving surgery. However, it has never been clear how much tissue surrounding the tumor bed needs to be irradiated, and whole-breast radiation therapy has been associated with both acute and chronic toxicity. Researchers are now looking at whether limited-field radiation therapy could be a better option for patients at low risk for recurrence.

Frank A. Vicini, M.D., of the William Beaumont Hospital in Royal Oak, Mich., and his colleagues compared rates of local recurrence between 199 women treated with limited-field radiation therapy and 199 matched control women treated with whole-breast radiation therapy. All of the women had early-stage breast cancer and were treated with breast-conserving surgery; women were matched by age, tumor size, lymph-node status, margins of excision, estrogen receptor status, and use of adjuvant tamoxifen therapy.

After five years of follow-up, there was no difference in the median time to recurrence and rate of local recurrence between women in the two treatment groups, nor was there any difference in the rates of distant metastases, disease-free survival, overall survival, or cause-specific survival.

"These results suggest that, in appropriately selected early-stage breast cancer patients, limited-field radiation therapy may be adequate in controlling residual disease after breast-conserving therapy," the researchers write, adding that these results raise the question of whether whole-breast radiation therapy is necessary in ce
'"/>

Contact: Linda Wang
jncimedia@oupjournals.org
301-841-1287
Journal of the National Cancer Institute
19-Aug-2003


Page: 1 2

Related medicine news :

1. Study of energy and health in Africa focuses spotlight on charcoal and forest management
2. Study shows promise in identifying kidney failure
3. Study shows patch therapy may be as effective as oral medications
4. Study shows soy is well accepted in school lunches
5. Study finds that coordinating care of chronically ill patients does not increase liability
6. Study provides new estimates of the causes of child mortality worldwide
7. Study finds factors linked to substance use disorder relapse among health care professionals
8. Study finds majority of women willing to accept cervical cancer vaccine for self and children
9. Study shows use of budesonide reduced the risk of asthma related events by 40% in children
10. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
11. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/13/2019)... ... ... A Place at Home has received the 2019 Best of ... Choice Award is granted only to the top-ranking home care providers, based on caregiver ... care. A Place at Home is ranked among the best employers of in-home caregivers ...
(Date:2/13/2019)... MESA, Calif. (PRWEB) , ... February 13, 2019 , ... ... healthcare scholarship. Open to students who choose to pursue a medical-related course of study ... describe their passion for substance abuse disorder and mental health treatment, and how it ...
(Date:2/13/2019)... ... February 13, 2019 , ... Dr. Christie Prendergast, ... Beauty network. , The Haute Beauty Network, well known for their exclusivity, ... Aesthetic surgeon and our newest addition to the Haute Living partnership. , ...
(Date:2/12/2019)... ... 12, 2019 , ... A technology company that aims to ... won the top award at the 9th annual SPIE Startup Challenge at Photonics ... pitch, nabbing a combined first prize of $15,000. Radiance 4D’s revolutionary 3D printing ...
(Date:2/12/2019)... ... February 12, 2019 , ... ... Solution to increase patient satisfaction, improve patient retention, and reduce patient outmigration for ... February 11-14. HIMSS provides Surgical Theater with a great venue to highlight ...
Breaking Medicine News(10 mins):
(Date:2/13/2019)... VEGAS (PRWEB) , ... February 13, 2019 , ... ... program in Bogotá, Colombia. The new program opens possibilities for childless couples who ... , Until now, childless couples have been limited to North America or ...
(Date:2/13/2019)... ... February 13, 2019 , ... ... the Public Private Partnership (PPP) between the Department of Health-Abu Dhabi (DoH) and ... first Health Information Exchange system (HIE), a centralized platform to streamline healthcare connectivity ...
(Date:2/13/2019)... ... February 13, 2019 , ... ... Thin Clients at HIMSS 2019 US in Orlando, Florida. The compact Thin Clients ... prices of $199 and $520 and above respectively. , Powered by Intel® ...
Breaking Medicine Technology:
Cached News: