HOME >> MEDICINE >> NEWS
Study examines three-day antibiotic regimens for treating bladder infection in women

CHICAGO A three-day regimen of the antibiotic amoxicillin-clavulanate is not as effective as ciprofloxacin at treating an uncomplicated bladder infection in women, according to a study in the February 23 issue of JAMA.

Acute uncomplicated urinary tract infections (UTIs) are among the most commonly encountered bacterial infections in women, according to background information in the article. Management of these infections has been made more complicated in recent years by increasing antimicrobial resistance, which has led to increased use of alternative antibiotics. There have been no published studies on the efficacy of one such antibiotic, amoxicillin-clavulanate, in the treatment of acute cystitis (inflammation of the urinary bladder) in the current era of high-level amoxicillin resistance.

Thomas M. Hooton, M.D., of the University of Washington and Harborview Medical Center, Seattle, and colleagues conducted a randomized trial that compared 3-day regimens of amoxicillin-clavulanate and ciprofloxacin for treatment of women with acute uncomplicated cystitis and used follow-up to evaluate the women for recurrent infection. Ciprofloxacin is in the fluoroquinolone class of antibiotics, a potent and frequently prescribed group that has shown increasing resistance. The trial included 370 women, aged 18 to 45 years. Subjects were randomly assigned to receive amoxicillin-clavulanate (500 mg/125 mg twice daily) or ciprofloxacin (250 mg twice daily) for 3 days and were followed for 4 months.

The researchers found that clinical cure resolution of the symptoms associated with UTI was observed in 93 (58 percent) of 160 women treated with amoxicillin-clavulanate compared with 124 (77 percent) of 162 women treated with ciprofloxacin. Amoxicillin-clavulanate was not as effective as ciprofloxacin even among women infected with bacterial strains susceptible to amoxicillin-clavulanate (65 [60 percent] of 109 women in the amoxicillin-clavulanate group vs. 114
'"/>

Contact: Susan Gregg-Hanson
206-731-4097
JAMA and Archives Journals
22-Feb-2005


Page: 1 2

Related medicine news :

1. Study of energy and health in Africa focuses spotlight on charcoal and forest management
2. Study shows promise in identifying kidney failure
3. Study shows patch therapy may be as effective as oral medications
4. Study shows soy is well accepted in school lunches
5. Study finds that coordinating care of chronically ill patients does not increase liability
6. Study provides new estimates of the causes of child mortality worldwide
7. Study finds factors linked to substance use disorder relapse among health care professionals
8. Study finds majority of women willing to accept cervical cancer vaccine for self and children
9. Study shows use of budesonide reduced the risk of asthma related events by 40% in children
10. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
11. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/2/2018)... ... August 02, 2018 , ... ... image e-sharing platform to connect clinicians inside and outside the network to vital ... stroke or trauma. , AHN joins other leading hospital systems nationwide in using ...
(Date:8/2/2018)... ... August 02, 2018 , ... Training ... Top 20 Training Delivery Companies of 2018 . The selection recognizes TGA’s award-winning, ... training industry professionals with the game-based tools they need to be successful, and ...
(Date:8/2/2018)... ... 2018 , ... Primary care practices in Rochester, N.Y., are ... recommendations for victims and their doctors. , A team of researchers and advocates ... developed the software program. , “Family care practitioners are often the first place ...
(Date:8/2/2018)... ... August 02, 2018 , ... Tunstall Americas has launched their ... can partner with Tunstall Americas for After-hours call-handling, Overflow call-handling, and Appointment Scheduling ... expand their suite of Patient Access Solutions, and gives their existing and new ...
(Date:8/1/2018)... ... August 01, 2018 , ... August marks National Immunization ... up-to-date on all immunizations. Vaccinations protect both large and small animals against an array ... pet owners is key to sustaining a pet's health and preventing the spread of ...
Breaking Medicine News(10 mins):
(Date:8/9/2018)... ... August 09, 2018 , ... National Day Calendar ... named the exclusive sponsor. , “We’re honored to have been selected as this ... for CBD on a national level,” said cbdMD’s Chief Scientific Officer, Dr. Justin ...
(Date:8/7/2018)... ... August 07, 2018 , ... Penn State ... spinal fusion alternatives, has begun training and certifying spine physicians across the United ... fourteen physicians received training at the Weill Cornell Brain and Spine Center in ...
(Date:8/3/2018)... N.J. (PRWEB) , ... August 03, 2018 , ... Flexefits, ... for passing H.R. 6199, especially for its allowing participants in Direct Primary Care arrangements ... covered by HSAs (capped at $150 per individual and $300 per family per month.) ...
Breaking Medicine Technology:
Cached News: