HOME >> MEDICINE >> NEWS
Study examines three-day antibiotic regimens for treating bladder infection in women

CHICAGO A three-day regimen of the antibiotic amoxicillin-clavulanate is not as effective as ciprofloxacin at treating an uncomplicated bladder infection in women, according to a study in the February 23 issue of JAMA.

Acute uncomplicated urinary tract infections (UTIs) are among the most commonly encountered bacterial infections in women, according to background information in the article. Management of these infections has been made more complicated in recent years by increasing antimicrobial resistance, which has led to increased use of alternative antibiotics. There have been no published studies on the efficacy of one such antibiotic, amoxicillin-clavulanate, in the treatment of acute cystitis (inflammation of the urinary bladder) in the current era of high-level amoxicillin resistance.

Thomas M. Hooton, M.D., of the University of Washington and Harborview Medical Center, Seattle, and colleagues conducted a randomized trial that compared 3-day regimens of amoxicillin-clavulanate and ciprofloxacin for treatment of women with acute uncomplicated cystitis and used follow-up to evaluate the women for recurrent infection. Ciprofloxacin is in the fluoroquinolone class of antibiotics, a potent and frequently prescribed group that has shown increasing resistance. The trial included 370 women, aged 18 to 45 years. Subjects were randomly assigned to receive amoxicillin-clavulanate (500 mg/125 mg twice daily) or ciprofloxacin (250 mg twice daily) for 3 days and were followed for 4 months.

The researchers found that clinical cure resolution of the symptoms associated with UTI was observed in 93 (58 percent) of 160 women treated with amoxicillin-clavulanate compared with 124 (77 percent) of 162 women treated with ciprofloxacin. Amoxicillin-clavulanate was not as effective as ciprofloxacin even among women infected with bacterial strains susceptible to amoxicillin-clavulanate (65 [60 percent] of 109 women in the amoxicillin-clavulanate group vs. 114
'"/>

Contact: Susan Gregg-Hanson
206-731-4097
JAMA and Archives Journals
22-Feb-2005


Page: 1 2

Related medicine news :

1. Study of energy and health in Africa focuses spotlight on charcoal and forest management
2. Study shows promise in identifying kidney failure
3. Study shows patch therapy may be as effective as oral medications
4. Study shows soy is well accepted in school lunches
5. Study finds that coordinating care of chronically ill patients does not increase liability
6. Study provides new estimates of the causes of child mortality worldwide
7. Study finds factors linked to substance use disorder relapse among health care professionals
8. Study finds majority of women willing to accept cervical cancer vaccine for self and children
9. Study shows use of budesonide reduced the risk of asthma related events by 40% in children
10. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
11. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women

Post Your Comments:
(Date:6/29/2015)... La Mirada, CA (PRWEB) , ... June 29, ... ... organizations, is honored to welcome fellowship-trained spine surgeon, Dr. John A. Mitamura, MD., ... will be practicing in Southern California locations including Long Beach , Irwindale ...
(Date:6/29/2015)... ... June 29, 2015 , ... Healthpointe ... its multidisciplinary group of physicians and specialists. Dr. Cook is experienced with providing ... in hopes of achieving outstanding medical outcomes. , “We are very excited to ...
(Date:6/29/2015)... ... June 29, 2015 , ... ... group series as part of its support program. This discussion series is part ... and other support services to those affected by mesothelioma. , The six week ...
(Date:6/29/2015)... ... June 29, 2015 , ... Healthpointe, one of Southern California’s ... newest FAA-certified medical examiner in the city of Colton . , The ... to obtain their physical aviation certificates. Pilots hoping to navigate airplanes, helicopters, gyroplanes, ...
(Date:6/29/2015)... ... June 29, 2015 , ... ... the weekend edition of USA TODAY. This 12-page, glossy, full-color special section hit ... in highly targeted markets totaling approximately 450,000 copies, with an estimated readership of ...
Breaking Medicine News(10 mins):Health News:Renowned Orthopedic and Spine Surgeon Joins Healthpointe in Long Beach 2Health News:Renowned Orthopedic and Spine Surgeon Joins Healthpointe in Long Beach 3Health News:Healthpointe in La Tijera Proudly Announces the Addition of a New Chiropractor 2Health News:Healthpointe in La Tijera Proudly Announces the Addition of a New Chiropractor 3Health News:Mesothelioma Organization Provides Support for Patients and Families 2Health News:Mesothelioma Organization Provides Support for Patients and Families 3Health News:Healthpointe Now Offering FAA Physical Exams in San Bernardino County 2Health News:Mediaplanet partners with USA TODAY and Kris Letang to raise awareness about the risk of heart attack and stroke 2
(Date:6/29/2015)... CAMBRIDGE, Mass. , June 29, 2015  Daktari Diagnostics ... Ceremony with the Technology in the Service of Society Award. ... IEEE President-Elect, Barry L. Shoop presented the award ... of Daktari. The ceremony was held Saturday, June 20, 2015, ... York, NY . "I have spent ...
(Date:6/29/2015)... KALAMAZOO, Mich. , June 29, 2015 /PRNewswire/ ... Association and American Stroke Association give hope for ... patients who experience an acute ischemic stroke each ... of the key products used in the clinical ... The new AHA/ASA guidelines strongly recommend endovascular ...
(Date:6/29/2015)... VILLAGE, Nev. , June 29, 2015  PDL ... it has entered into a credit agreement with CareView ... with up to $40 million of secured debt financing. ... industry focused on patient care monitoring. Under ... to $40 million of debt financing in two tranches ...
Breaking Medicine Technology:Daktari Honored with IEEE Spectrum Award 2New AHA Guidelines For The Early Management And Treatment Of Stroke Will Change The Standard Of Care For Thousands Of Stroke Patients Each Year 2New AHA Guidelines For The Early Management And Treatment Of Stroke Will Change The Standard Of Care For Thousands Of Stroke Patients Each Year 3PDL BioPharma Announces $40 Million Financing Transaction with CareView Communications 2PDL BioPharma Announces $40 Million Financing Transaction with CareView Communications 3PDL BioPharma Announces $40 Million Financing Transaction with CareView Communications 4
Cached News: