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Study finds racial differences in survival rates after prostate cancer treatment

CHAPEL HILL -- Black men tend to have poorer overall survival rates than white men after being treated for localized prostate cancer, a new study shows.

The findings, to be published in Wednesday's (Nov. 19) issue of the Journal of the National Cancer Institute, also show the greatest disparity to be among men who undergo surgery.

The study's lead author is Dr. Paul Godley, associate professor of medicine and epidemiology at the University of North Carolina at Chapel Hill, member of the UNC Lineberger Comprehensive Cancer Center and leader of the UNC Program on Ethnicity, Culture and Health Outcomes. He was joined by researchers from UNC's schools of medicine and public health, the Medical Review of North Carolina and Massachusetts General Hospital.

The study involved 5,747 black men and 38,242 white men with clinically localized prostate cancer. Researchers found that among those who had surgery, the median survival time for black patients was 1.8 years less than for white patients (10.8 years versus 12.6 years, respectively).

The differences in median survival times between black and white patients were smaller among patients treated with radiation therapy ( .7 years) and among patients who had non-aggressive therapy, also called "watchful waiting" (1.0 years).

About 75 percent of the estimated 189,100 prostate cancers diagnosed nationwide in 2002 were clinically localized at the time of diagnosis, so any disparities in outcomes among such patients are of great interest, Godley said. Clinically localized cancer is disease confined to the prostate.

Scientists merged the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) data with Medicare file information to compile their findings.

"Previous research into prostate cancer outcome disparities assumed that patients receiving similar treatment would have similar medical outcomes," said Godley. "We felt it was importan
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Contact: Dianne Shaw
919-966-7834
University of North Carolina at Chapel Hill
18-Nov-2003


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