HOME >> MEDICINE >> NEWS
Study finds widespread sympathetic nerve damage in Parkinson's disease

For years, researchers have known that the symptoms of Parkinson's disease (PD) result from damage to a specific region of the brain. A new study shows that the disease also causes widespread damage to the sympathetic nervous system, which controls blood pressure, pulse rate, perspiration, and many other automatic responses to stress. The findings help explain the blood pressure regulation problems commonly found in PD and may lead to new treatments for the disease.

Physicians have long known that patients with PD often have incontinence and other symptoms of autonomic nervous system function, and previous studies have found evidence of sympathetic nerve damage in PD patients' hearts. The sympathetic nervous system is one component of the autonomic nervous system. However, this study is the first to show that the disease affects sympathetic nerve endings in the thyroid gland and the kidney, says David S. Goldstein, M.D., Ph.D., of the National Institute of Neurological Disorders and Stroke in Bethesda, Maryland, who led the study. It also shows that this damage is unrelated to treatment with the most commonly used Parkinson's drug, levodopa. The study appears in the April 23, 2002, issue of Neurology.*

Many people with PD develop a problem called orthostatic hypotension (OH), in which blood pressure falls suddenly when a person stands up. This condition can lead to dizziness, lightheadedness, and fainting. OH increases the risk of falls and other types of accidents, which can be disabling or even life-threatening. Patients with PD frequently have other symptoms of sympathetic nervous system failure, including intolerance to heat or cold and sexual dysfunction. However, the underlying cause of these problems has been unclear.

In the study, the researchers examined 18 patients with PD and OH, 23 patients with PD only, and 16 normal volunteers. The participants were given positron emission tomography (PET) scans of the heart, kidney,
'"/>

Contact: Paul Girolami or Natalie Frazin
301-496-5751
NIH/National Institute of Neurological Disorders and Stroke
22-Apr-2002


Page: 1 2 3

Related medicine news :

1. Study of energy and health in Africa focuses spotlight on charcoal and forest management
2. Study shows promise in identifying kidney failure
3. Study shows patch therapy may be as effective as oral medications
4. Study shows soy is well accepted in school lunches
5. Study finds that coordinating care of chronically ill patients does not increase liability
6. Study provides new estimates of the causes of child mortality worldwide
7. Study finds factors linked to substance use disorder relapse among health care professionals
8. Study finds majority of women willing to accept cervical cancer vaccine for self and children
9. Study shows use of budesonide reduced the risk of asthma related events by 40% in children
10. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
11. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women

Post Your Comments:
(Date:5/26/2015)... 26, 2015 The skin cancer melanoma ... caught early. Melanoma is also easily prevented. Worldwide, according ... the melanoma rate is on the upswing due to ... risk for indoor tanning salon patrons is unclear, many ... recent ban, in Pennsylvania, coincides with the American Cancer ...
(Date:5/26/2015)... (PRWEB) May 26, 2015 On June ... a complimentary live online broadcast at 6:00pm PST/9:00 pm ... and Trivedi Master™ Alice Branton welcomes the public to ... a night of profound knowledge, transformation and enlightenment. ... Effect® and no previous knowledge, experience or other prerequisites ...
(Date:5/26/2015)... MN (PRWEB) May 26, 2015 Learning ... product line, Nutrition Education Cards . These cards ... Featuring engaging photography and simple, easy-to-read text, these new ... educators . They offer practical nutrition tips and suggestions ... Current titles available are: , + MyPlate: Eat for ...
(Date:5/26/2015)... CUES (Credit Union Executives Society), an ... union CEOs, directors and future leaders, will make “healthy ... line. CUES chose hubbub health , a unique ... unions across the country, to improve its overall employee ... Report from the Credit Union National Association (CUNA), ...
(Date:5/26/2015)... 26, 2015 General Networks Corporation ... Corporation. The alliance ensures joint customers will benefit ... General Networks’ expertise in building enterprise content and ... will help customers integrate, manage and operationalize their ... processes. , “Our customers are seeking tools to ...
Breaking Medicine News(10 mins):Health News:Skin Cancer Awareness Month: Pennsylvania Ban of Teens from Tanning Salons Is Praised by Fresh Water Advocate Sharon Kleyne 2Health News:Skin Cancer Awareness Month: Pennsylvania Ban of Teens from Tanning Salons Is Praised by Fresh Water Advocate Sharon Kleyne 3Health News:The Human Wellness Company Trivedi Master Wellness™ Opens a Complimentary Transformational Community Call to the Public on June 4, 2015 2Health News:The Human Wellness Company Trivedi Master Wellness™ Opens a Complimentary Transformational Community Call to the Public on June 4, 2015 3Health News:Learning ZoneXpress Introduces New Educational Resource for WIC, SNAP-Ed, and EFNEP 2Health News:CUES Expects a Positive Return on Wellness with hubbub health™ 2Health News:CUES Expects a Positive Return on Wellness with hubbub health™ 3Health News:General Networks Corporation Announces Alliance with MarkLogic 2
(Date:5/26/2015)... CytoSorbents Corporation (NASDAQ: CTSO ), a ... cytokine adsorber to purify blood and control severe inflammation, ... Officer, will make an overview presentation at the LD ... PDT / 1:30PM EDT at the Luxe Hotel in ... will also be available to participate in one-on-one meetings, ...
(Date:5/26/2015)... 2015  RXi Pharmaceuticals Corporation (NASDAQ: ... discovering and developing innovative therapies primarily in ... that the Company,s President and CEO, Dr. ... the Jefferies 2015 Global Healthcare Conference on ... EDT. Dr. Cauwenbergh will present a corporate ...
(Date:5/26/2015)... , May 26, 2015 Egalet Corporation ... specialty pharmaceutical company focused on developing, manufacturing and ... Bob Radie , president and chief executive officer, ... June. He will provide an update on Egalet,s ... tromethamine) Nasal Spray, approved product OXAYDO ™ ...
Breaking Medicine Technology:CytoSorbents to Present at the LD Micro Invitational on June 1st 2CytoSorbents to Present at the LD Micro Invitational on June 1st 3RXi Pharmaceuticals to Present at the Jefferies 2015 Global Healthcare Conference 2RXi Pharmaceuticals to Present at the Jefferies 2015 Global Healthcare Conference 3RXi Pharmaceuticals to Present at the Jefferies 2015 Global Healthcare Conference 4Egalet to Present at Upcoming Conferences in June 2Egalet to Present at Upcoming Conferences in June 3
Cached News: