HOME >> MEDICINE >> NEWS
Study finds widespread sympathetic nerve damage in Parkinson's disease

For years, researchers have known that the symptoms of Parkinson's disease (PD) result from damage to a specific region of the brain. A new study shows that the disease also causes widespread damage to the sympathetic nervous system, which controls blood pressure, pulse rate, perspiration, and many other automatic responses to stress. The findings help explain the blood pressure regulation problems commonly found in PD and may lead to new treatments for the disease.

Physicians have long known that patients with PD often have incontinence and other symptoms of autonomic nervous system function, and previous studies have found evidence of sympathetic nerve damage in PD patients' hearts. The sympathetic nervous system is one component of the autonomic nervous system. However, this study is the first to show that the disease affects sympathetic nerve endings in the thyroid gland and the kidney, says David S. Goldstein, M.D., Ph.D., of the National Institute of Neurological Disorders and Stroke in Bethesda, Maryland, who led the study. It also shows that this damage is unrelated to treatment with the most commonly used Parkinson's drug, levodopa. The study appears in the April 23, 2002, issue of Neurology.*

Many people with PD develop a problem called orthostatic hypotension (OH), in which blood pressure falls suddenly when a person stands up. This condition can lead to dizziness, lightheadedness, and fainting. OH increases the risk of falls and other types of accidents, which can be disabling or even life-threatening. Patients with PD frequently have other symptoms of sympathetic nervous system failure, including intolerance to heat or cold and sexual dysfunction. However, the underlying cause of these problems has been unclear.

In the study, the researchers examined 18 patients with PD and OH, 23 patients with PD only, and 16 normal volunteers. The participants were given positron emission tomography (PET) scans of the heart, kidney,
'"/>

Contact: Paul Girolami or Natalie Frazin
301-496-5751
NIH/National Institute of Neurological Disorders and Stroke
22-Apr-2002


Page: 1 2 3

Related medicine news :

1. Study of energy and health in Africa focuses spotlight on charcoal and forest management
2. Study shows promise in identifying kidney failure
3. Study shows patch therapy may be as effective as oral medications
4. Study shows soy is well accepted in school lunches
5. Study finds that coordinating care of chronically ill patients does not increase liability
6. Study provides new estimates of the causes of child mortality worldwide
7. Study finds factors linked to substance use disorder relapse among health care professionals
8. Study finds majority of women willing to accept cervical cancer vaccine for self and children
9. Study shows use of budesonide reduced the risk of asthma related events by 40% in children
10. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
11. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/21/2017)... ... 21, 2017 , ... Northern California Medical Associates ... Symposium on April 1, 2017 in Santa Rosa. This well-attended annual conference plays ... an opportunity to learn about cutting edge treatments, to collaborate, share research and ...
(Date:4/21/2017)... CA (PRWEB) , ... April 21, 2017 , ... Providing ... not understand the estate planning process, or where to even begin. “Now more than ... if you are to properly protect yourself and your family,” said attorney Lisa Edgar ...
(Date:4/21/2017)... ... 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh in Abilene, Texas, ... a global crisis with solution to peace plan. Yisrayl says war has never brought peace ... given by the Creator Himself. , Yisrayl says war drums are beating all over ...
(Date:4/21/2017)... ... April 21, 2017 , ... ... are five common elements between the Obamacare program that most Republicans love to ... uses Warfarin poison to kill hogs. , Like Obamacare, the Miller program ...
(Date:4/21/2017)... , ... April 21, 2017 , ... National pest management ... in the number of bed bug infestations over the 5-year period. In 2015 10% ... from the treatment of bed bug infested properties. , The health and economic consequences ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... April 20, 2017  AbbVie (NYSE: ABBV), a ... (n=145/146) of chronic hepatitis C virus (HCV) infected ... 6 and compensated cirrhosis (Child-Pugh A) achieved sustained ... ) with its investigational, pan-genotypic regimen of glecaprevir/pibrentasvir ... seen following 12 weeks of G/P treatment without ...
(Date:4/20/2017)... Sweden , April 20, 2017 ... NEVPF) ("NeuroVive") today announced positive preclinical results ... preclinical compound for non-alcoholic steatohepatitis (NASH), in ... NV556 has previously shown ... NASH model. Today, NeuroVive,s scientists present novel ...
(Date:4/19/2017)... , April 19, 2017 Cardiology devices segment ... projected period The Cardiology Devices segment is likely ... US$ 15 Mn in 2018 over 2017. By the end ... market valuation close to US$ 700 Mn, expanding at a ... segment dominated the Asia Pacific reprocessed ...
Breaking Medicine Technology:
Cached News: