Study identifies factors associated with long-term opioid treatment of veteran patients

CHICAGO Veteran patients who receive long-term opioid prescriptions generally are treated with modest and stable medication dosages, according to an article in the November 22 issue of The Archives of Internal Medicine, one of the JAMA/Archives journals.

"The long-term use of opioids for the treatment of chronic pain of nonmalignant [noncancerous] origin has been generally supported by specialists in pain management as a less than ideal but often necessary and humane course of treatment," according to background information in the article. Long-term opioid use can by complicated by problematic dose increases, drug dependency, and toxic effects.

John A. Hermos, M.D., from Boston University School of Public Health, and colleagues analyzed pharmacy and clinical databases in order to determine characteristics of prescribing patterns and to identify potential high-risk opioid prescribing. Data on durations, doses, and dose changes of oxycodone/acetaminophen and concurrent use of long-acting opioids, benzodiazepines, tricyclic antidepressants, and anticonvulsants were obtained from the Veterans Integrated Service Network for the New England region (VISN 1) from January 1998 through June 2001.

The researchers found that during the study period, 47,302 patients received 177,840 prescriptions (initial and renewed prescriptions) for short-acting opioid medications, and 6,936 received 53,083 prescriptions for long-acting opioids. Two thousand one hundred ninety-five patients (31 percent with cancer) received oxycodone/acetaminophen for more than nine months at an average prescribed dose of 3.9 tablets per day, without significant changes in daily prescribed average dose over time. Patients with cancer were more likely to receive other long-acting opioids simultaneously. In those without cancer, high daily average doses were associated with duration, older age, HIV and/or AIDS, and with prescription of benzodiazepines and long-acting opioids.

Contact: Jodi Petrie
JAMA and Archives Journals

Page: 1 2

Related medicine news :

1. Study of energy and health in Africa focuses spotlight on charcoal and forest management
2. Study shows promise in identifying kidney failure
3. Study shows patch therapy may be as effective as oral medications
4. Study shows soy is well accepted in school lunches
5. Study finds that coordinating care of chronically ill patients does not increase liability
6. Study provides new estimates of the causes of child mortality worldwide
7. Study finds factors linked to substance use disorder relapse among health care professionals
8. Study finds majority of women willing to accept cervical cancer vaccine for self and children
9. Study shows use of budesonide reduced the risk of asthma related events by 40% in children
10. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
11. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women

Post Your Comments:

(Date:8/31/2020)... , ... August 31, 2020 , ... ... working, both directly with persons with autism and other developmental disabilities, as well ... early intervention, parent education, adolescents with autism, school consultation, and staff development. She ...
(Date:8/29/2020)... (PRWEB) , ... August 29, 2020 , ... When professor ... perhaps with greater ease than most people would. Rather than become melancholic, however, he ... deep advice on achieving one’s dreams. Randy Pausch took a negative situation and turned ...
(Date:8/28/2020)... TUCSON, Ariz. (PRWEB) , ... August 28, 2020 ... ... helium-oxygen respiratory assist system designed to help treat patients with respiratory conditions, including ... a mixture of helium and oxygen, but it captures exhaled gas and scrubs ...
(Date:8/28/2020)... ... August 28, 2020 , ... With in-person gluten-free ... to continue helping the specialty-diet community connect with great, gluten-free brands. At the ... enter giveaways, chat with brands & watch over 50 educational classes... all online ...
(Date:8/28/2020)... ... August 28, 2020 , ... ... Adventist Health on its investment in Synchronous Health, a tech-enabled behavioral health and ... the strength of human empathy with artificial intelligence (AI) to increase access and ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... Neil Oberfeld of global law ... the Board of Trustees and committee chair of the Governance Committee for Mile ... nonprofit organization that fights for the education, health, and financial stability of residents ...
(Date:9/1/2020)... ... September 01, 2020 , ... September is National Ovarian Cancer Awareness ... deaths than any other cancer of the female reproductive system. The American Cancer ... and about 14,000 women will die from this disease. Throughout the month of ...
(Date:8/31/2020)... ... August 31, 2020 , ... Continuing on ... a broad-spectrum sanitization, disinfection and deodorization provider - is proud to announce it ... disinfecting services for businesses and residents throughout the area. , Germinator provides a ...
Breaking Medicine Technology:
Cached News: