HOME >> MEDICINE >> NEWS
Study sheds light on cross-species infection for BSE

A study published early online by THE LANCET provides an estimate of the compared efficiency of oral transmission of BSE to cattle and to man.

There has been uncertainty regarding the amount of BSE material that constitutes an oral infectious dose for humans. The study estimates that a person would have to eat at least 1.5kg of neural tissue from an infected animal that was just below the detection limit when tested negative at the slaughterhouse, to be at risk of developing variant Creutzfeldt-Jakob disease (vCJD).

Jean-Phillipe Deslys (Commissariat l'Energie Atomique, France) and colleagues gave two adult primates a 5g oral dose of ground brain tissue from a BSE-affected cow. One primate developed a neurological disease closely resembling vCJD 5 years after exposure, whereas the other remained free of disease. On the basis of these findings and data from other studies the investigators estimated that the efficiency of infection from cow to primate could be 7 to 20 times lower than that of intraspecies infection for cattle.

The results of the present study also suggest that the incubation period for BSE transmission from cattle to human can be more than a third longer than that of human to human transmission.

Dr Deslys states: "The present data do not provide a definitive minimum infective dose for transmission of cattle BSE to primates, but they do give enough information for a preliminary assessment of the adequacy of existing measures to protect the human food chain.

"Our results provide reassurance that BSE screening procedures combined with CNS removal are effective measures to protect the human food chain."

In an accompanying commentary James Ironside and Mark Head (National Creutzfeldt-Jakob Disease Surveillance Unit, University of Edinburgh, UK) write that the precise implications of this study for vCJD are difficult to assess since the number of animals used in the study were small and the minimum infect
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
26-Jan-2005


Page: 1 2

Related medicine news :

1. Study of energy and health in Africa focuses spotlight on charcoal and forest management
2. Study shows promise in identifying kidney failure
3. Study shows patch therapy may be as effective as oral medications
4. Study shows soy is well accepted in school lunches
5. Study finds that coordinating care of chronically ill patients does not increase liability
6. Study provides new estimates of the causes of child mortality worldwide
7. Study finds factors linked to substance use disorder relapse among health care professionals
8. Study finds majority of women willing to accept cervical cancer vaccine for self and children
9. Study shows use of budesonide reduced the risk of asthma related events by 40% in children
10. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
11. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... ... 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic treatment ... Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. This ... of the world’s leading providers of cereal and other breakfast foods. Its residents often ...
(Date:6/26/2016)... ... June 26, 2016 , ... ... they have been diagnosed with endometriosis. These women need a treatment plan to ... a comprehensive approach that can help for preservation of fertility and ultimately achieving ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX ... Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over ... Cut Pro X . Simply select a ProHand generator and drag it above media ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of ... recognition of their exemplary accomplishments in worksite health promotion. , The Wellness at Work ... Symposium at the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses ...
(Date:6/24/2016)... ... 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. In ... benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued ... Sickle Cell Disease (SCD) is a disorder of the red blood cells, which can ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 , , , ... 7, 2016 , , , , LOCATION: , , , ... , , , EXPERT PANELISTS:  , , , Frost & Sullivan,s ... Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program ... global pharmaceutical industry is witnessing an exceptional era. Several new demand ...
(Date:6/23/2016)... PRINCETON, N.J. , June 23, 2016  Guerbet ... of Premier Inc.,s Supplier Horizon Award . ... this year, Guerbet was recognized for its support of ... value creation through clinical excellence, and commitment to lower ... delighted to receive this recognition of our outstanding customer ...
(Date:6/23/2016)... NEW YORK , June 23, 2016 ... rough waters, but it continues to present great opportunities ... featured companies for today: Intrexon Corp. (NYSE: ... ), Arena Pharmaceuticals Inc. (NASDAQ: ARNA ), ... Learn more about these stocks and receive your complimentary ...
Breaking Medicine Technology:
Cached News: