The Latest Biology News And Medical NewsBiology News 2Health News 2Biology News 3Health News 3
HOME >> MEDICINE >> NEWS
Study shows weight-based REBETOL dosing in combination with PEG-INTRON significantly improves ...

Study shows weight-based REBETOL dosing in combination with PEG-INTRON significantly improves viral clearance in African-American patients with most-difficult-to-treat form of hepatitis C

WIN-R study provides important insights on improving hepatitis C treatment among African-Americans

(BOSTON, Oct. 29, 2004) Twice as many African-American patients infected with the most difficult-to-treat form of chronic hepatitis C successfully cleared the virus when given a weight-based dose of REBETOL (ribavirin, USP) rather than a flat dose, in combination with PEG-INTRON (peginterferon alfa-2b), according to data presented at a Presidential Plenary session at the 55th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) on Monday, November 1, at noon. The new findings, involving nearly 400 African-American patients from the large multicenter WIN-R study, are significant because African-Americans are known to have generally lower rates of response to hepatitis C therapy, and efforts are underway to improve outcomes for these patients.

"These results show that individualized therapy with weight-based ribavirin offers a significant advantage over a flat dose of ribavirin in the treatment of African-American patients chronically infected with hepatitis C genotype 1, the most difficult form of the virus to treat," said study principal investigator Ira M. Jacobson, M.D., Vincent Astor Professor of Clinical Medicine at Weill Cornell Medical College and chief of the division of gastroenterology and hepatology at NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City. "It's also important to note that in this study the overall safety of weight-based ribavirin dosing was similar to that of the flat 800 mg dose," he said.

The WIN-R (Weight-Based Dosing of PEG-INTRON and REBETOL ) study is the largest prospective clinical study in hepatitis C undertaken to date, involvi
'"/>


29-Oct-2004


Page: 1 2 3 4

Related medicine news :

1. Study of energy and health in Africa focuses spotlight on charcoal and forest management
2. Study shows promise in identifying kidney failure
3. Study shows patch therapy may be as effective as oral medications
4. Study shows soy is well accepted in school lunches
5. Study finds that coordinating care of chronically ill patients does not increase liability
6. Study provides new estimates of the causes of child mortality worldwide
7. Study finds factors linked to substance use disorder relapse among health care professionals
8. Study finds majority of women willing to accept cervical cancer vaccine for self and children
9. Study shows use of budesonide reduced the risk of asthma related events by 40% in children
10. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
11. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women

Post Your Comments:
(Date:11/23/2009)...Newswire/--XiotechCorporationtodayannouncedthatMas...000storagesystem,poweredbyIntelligentStorageElemen...eneeds,enablefuturegrowthanddeliversignificantcapi...r. ,, MasonGeneral,locatedinShelton,Wash.,wasra...ostWired-Rural"hospitalsin2008and2009foritssuperio...
(Date:11/23/2009)...e/--Thanksgivingweekendmarksthe36thannualStateFarm...representsthesportsmanshipandprideoftwoschoolsbuti...seinattendance. ,, ForthecrewofthenewU.S.CoastG...beforetheyworktotestandlaunchabrandnewshiptoprotec...yOfficerClaudeBovellandtherestofthecrewwillbeginte...
(Date:11/23/2009)...g flaxseed oil to the diet could reduce the risk o...with diabetes, according to a report to be publish...utrition and Public Health . , Mer Harvi and col... Egypt, have studied the effect of diabetes on bon...t might delay the onset of osteoporosis. The resea...
(Date:11/23/2009)...ly modified to produce bacterial proteins that are...ve been planted on more than 200 million hectares ... after the bacterium Bacillus thuringiensis , com...lowing farmers to save money and lessen environmen...wever, since insects can evolve resistance to toxi...
(Date:11/23/2009)...prove patient outcomes, research suggests , ...mbination drug therapy shows promise in treating p...rchers say. , The study from the Massachusetts ...t survival and tumor response in patients treated ...tor that has helped slow the growth of other cance...
Breaking Medicine News(10 mins):Health News:ISE Technology by Xiotech Helps Hospital Achieve Data Center Efficiency, Savings 2Health News:Nothing Is Like Being There 2Health News:Flaxseed oil and osteoporosis 2Health News:Insect resistance to Bt crops can be predicted, monitored and managed 2Health News:Combo Treatment Beneficial in Biliary-Tract Cancer Study 2
(Date:11/23/2009)...O,Calif.,Nov.23/PRNewswire-FirstCall/--Anesiva,Inc...r.DavidC.U,PrichardhaveagreedtojointheAnesivaboard...etweenAnesivaandArcionTherapeutics.Completionofthe...aceatthepreviouslyannouncedAnesiva2009AnnualMeetin...PSTat400OysterPoint,Suite107A,SouthSanFrancisco,Ca...
(Date:11/23/2009)...v.23/PRNewswire-FirstCall/--RaptorPharmaceuticalCo...nouncedresultsfromaPhase2bclinicaltrialofitspropri...mine")inpatientswithnephropathiccystinosis("cystin...ia,SanDiego("UCSD")GeneralClinicalResearchCenter,e...rmacodynamicsofasingledoseofDRCysteamineinninecyst...
(Date:11/23/2009)...AZER,Pa.,Nov.23/PRNewswire-FirstCall/--CeptionTher...ny,andCephalon,Inc.(Nasdaq: CEPH )todayannouncedre...reslizumab)asatreatmentforpediatriceosinophiliceso...mentintheco-primaryendpointsofchangesinesophageale...taindicatedthatpatientstreatedwithCINQUILshowedast...
Breaking Medicine Technology:Anesiva Announces Prospective Board Members To Be Appointed Upon Successful Completion of Proposed Merger 2Anesiva Announces Prospective Board Members To Be Appointed Upon Successful Completion of Proposed Merger 3Raptor Pharmaceutical Completes DR Cysteamine Phase 2b Clinical Trial in Cystinosis 2Raptor Pharmaceutical Completes DR Cysteamine Phase 2b Clinical Trial in Cystinosis 3Raptor Pharmaceutical Completes DR Cysteamine Phase 2b Clinical Trial in Cystinosis 4Raptor Pharmaceutical Completes DR Cysteamine Phase 2b Clinical Trial in Cystinosis 5Ception Therapeutics and Cephalon Provide Initial Results of a Phase IIb/III Study of CINQUIL in Pediatric Eosinophilic Esophagitis 2Ception Therapeutics and Cephalon Provide Initial Results of a Phase IIb/III Study of CINQUIL in Pediatric Eosinophilic Esophagitis 3Ception Therapeutics and Cephalon Provide Initial Results of a Phase IIb/III Study of CINQUIL in Pediatric Eosinophilic Esophagitis 4FDA Investigating Safety of Asthma Drug Xolair 51948 1FDA Investigating Safety of Asthma Drug Xolair 51948 2Does Your Child Need Vision Therapy 3F 51946 1Does Your Child Need Vision Therapy 3F 51946 2Does Your Child Need Vision Therapy 3F 51946 3Does Your Child Need Vision Therapy 3F 51946 4Cogdell Spencer ERDMAN 28SM 29 Announces the Signing of Contracts Totaling 2488 8 Million in Janesville Wisconsin 51944 1Cogdell Spencer ERDMAN 28SM 29 Announces the Signing of Contracts Totaling 2488 8 Million in Janesville Wisconsin 51944 2Cogdell Spencer ERDMAN 28SM 29 Announces the Signing of Contracts Totaling 2488 8 Million in Janesville Wisconsin 51944 3
Other News:
A common spermicide gel which has previously been proposed as a preventative agent against HIV-1 infection has been shown to be ineffective, according to authors of a study in this week's issue of The
...- Diabetic women who use hormone replacement thera...ose under control, and have lower cholesterol leve...udy by University at Buffalo epidemiologists has f... had lower total cholesterol levels, as well as hi...
This news release is also available in French.......Scientists have identified a protein fragment in many cereal grains that may cause the autoimmune disorder, Celiac Sprue, and an enzyme that may hel
The antibiotic azithromycin could offer some benefit to people with cystic fibrosis if they do not respond to conventional treatment, suggest authors of a study in this week's issue of The Lancet. ..
health news:Spermicide gel could increase risk of HIV-1 infection 2health news:Diabetic women on hormone replacement therapy have better glycemic and lipid profiles 2health news:'Glutaid' on the horizon? Study may someday spell relief for people on gluten-free diets 2health news:'Glutaid' on the horizon? Study may someday spell relief for people on gluten-free diets 3
... with liver disease before and after transplant fo... transplant showed the most improvement afterwards...ing transplant was common and identified several r...results of this study appear in the September 2006...
...ound two bacterial muscle infections common in tro... along with the emergence of community-acquired me...), according to a study published in the Oct. 15 i...e online....Staphylococcus aureus, or staph, is a ...
WHEN out in the sun, how often do you apply sunscreen? If it's anything less than once every 2 hours, you might be better off not using any in the first place.... So says Kerry Hanson, a chemist at th
...significant amount of data, medical information, a... departments, many websites are written well above...nd are inaccessible to people with dis-abilities a... Brown University researchers Darrell M. West and ...
health news:Bone mass continues to increase in liver transplant patients, despite early loss 2health news:Bone mass continues to increase in liver transplant patients, despite early loss 3health news:Study shows antibiotic-resistant bacteria responsible for increase in muscle infections 2health news:State health department Web sites inaccessible to many, study finds 2health news:State health department Web sites inaccessible to many, study finds 3