HOME >> MEDICINE >> NEWS
Study to examine if new eczema drug may prevent future development of asthma

CHICAGO - Children's Memorial Hospital is the only Chicago site for a study to determine whether early treatment of eczema using one of a new class of anti-inflammatory drugs will prevent subsequent development of asthma and other allergic diseases. Prevalence of eczema, or atopic dermatitis, has tripled in the last few decades, in parallel with asthma. Investigators at Children's Memorial are part of a national clinical trial involving 1,100 children, from 3 to 18 months old, to test pimecrolimus (Elidel), one of a new class of drugs called calcineurin inhibitors. Used in a cream form, pimecrolimus prevents the production of chemicals in the immune system that cause eczema symptoms, including redness, itching, cracking and bleeding.

The six-year prospective study, funded by Novartis, will be conducted in two stages. During the first three years a double blind study will compare the safety and effectiveness of pimecrolimus in conjunction with corticosteroid therapy for flare-ups, vs. corticosteroid therapy alone. Investigators hope that early treatment with pimecrolimus will reduce or prevent the need for corticosteroids. In the second three years, patients will be followed to see if they develop other allergic diseases, such as asthma, allergic rhinitis (hay fever), or allergic conjunctivitis (eye redness).

"The hope is that early and effective topical treatment of eczema in its early stages may help to prevent the later development of asthma, allergic rhinitis or allergic conjunctivitis," says Amy Paller, MD, lead site investigator and researcher at Children's Memorial Institute for Education and Research. Paller, head of dermatology at Children's Memorial, is professor of pediatrics and dermatology at Northwestern University's Feinberg School of Medicine.

"While eczema develops from birth to about three years of age in most affected children, other allergies such as asthma, begin in early childhood, and hay fever begins even later
'"/>

Contact: Ellen M. Hunt
ehunt@childrensmemorial.org
773-880-6908
Children's Memorial Hospital
18-Nov-2003


Page: 1 2

Related medicine news :

1. Study of energy and health in Africa focuses spotlight on charcoal and forest management
2. Study shows promise in identifying kidney failure
3. Study shows patch therapy may be as effective as oral medications
4. Study shows soy is well accepted in school lunches
5. Study finds that coordinating care of chronically ill patients does not increase liability
6. Study provides new estimates of the causes of child mortality worldwide
7. Study finds factors linked to substance use disorder relapse among health care professionals
8. Study finds majority of women willing to accept cervical cancer vaccine for self and children
9. Study shows use of budesonide reduced the risk of asthma related events by 40% in children
10. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
11. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2018)... ... October 12, 2018 , ... At HEI Health, we believe tomorrow’s healthcare can ... this year’s National Healthcare CXO Fall Summit by Marcus Evans. HEI will be hosting ... Patient Experience challenges with leading healthcare providers. , Marcus Evans National Healthcare CXO ...
(Date:10/13/2018)... ... ... Convoy of Hope’s Disaster Services Team is currently in Marianna, Florida — ... to serve hurricane survivors with water, food, baby products, hygiene kits, flood buckets, tarps ... of supplies are in motion to Florida. , Convoy’s walk-up and drive-thru ...
(Date:10/13/2018)... ... October 13, 2018 , ... The ... & Nutrition, has announced LaRhonda Burley as its new Vice President of Partnerships ... 2010 to support and strengthen the mission of the President's Council by generating ...
(Date:10/11/2018)... (PRWEB) , ... October 11, 2018 , ... ... for 2018. The medalists are leading scientists in their fields recognized by DuPont ... advancing science and technology relevant to the future of food, nutrition and health. ...
(Date:10/11/2018)... , ... October 11, 2018 , ... ... “insecure and quite vulnerable to manipulation,” warns former U.S. Department of Homeland Security ... Why We’re Vulnerable and How We Can Stop it. , Pointing to the ...
Breaking Medicine News(10 mins):
(Date:10/18/2018)... ... October 18, 2018 , ... ... off the Association’s year-long celebration of its 30th anniversary today with the launch ... course of a year and leveraging Member feedback, the new website offers state, ...
(Date:10/18/2018)... ... October 18, 2018 , ... The American Society for ... for Medicare & Medicaid Services (CMS) to develop pathology-related quality measures that will ... Payment Program (QPP). ASCP is among seven awardees – and the only pathology ...
(Date:10/17/2018)... ... October 17, 2018 , ... ... and advisory firm focused on high-growth niche markets, Artificial Intelligence in Healthcare ... true meaning of AI and learn from leading experts who are developing and ...
Breaking Medicine Technology:
Cached News: