Successful implementation of pilot study for HIV antiretroviral therapy in Uganda

Authors of a study in this week's issue of THE LANCET report on the successful implementation of a UNAIDS/Uganda Health Ministry initiative to provide antiretroviral treatment to people with HIV/AIDS in Uganda.

Little is known about how to implement complex HIV-1 treatment programmes in resource-limited countries. Paul Weidle from the Centers for Disease Control and Prevention, USA, and colleagues from Uganda assessed the UNAIDS/Uganda Ministry of Health HIV Drug Access Initiativeone of the first pilot antiretroviral programmes in Africain which patients paid for their medications at negotiated reduced prices.

912 patients were treated at five Ugandan centres; the investigators assessed the care of 476 patients at three centres, of whom 399 started antiretroviral therapy. Most patients accessed care at an advanced stage of HIV disease (median CD4 cell count 73 cells/mm3; viral load 193 817 copies/ml). Half the patients (51%) received highly active antiretroviral therapy (HAART), just under half (47%) received dual nucleoside reverse transcriptase inhibitors (2NRTIs), and 2% received a single NRTI.

An effective system for medical care and drug distribution was implemented resulting in an uninterrupted supply of drugs that supported sustainable management of patients. Patients returning for visits reported good adherence to treatment and achieved beneficial virologic and immunologic responses similar to those seen in more developed settings. The percentage of patients surviving and staying on therapy at six months was 63% and at one-year was 49%. Those with most advanced disease, a CD4 white blood cell count of less than 50 per microlitre of blood, were nearly three times as likely to die.

Paul Weidle comments: "This pilot programme showed that AIDS patients in a developing country can be managed successfully with antiretroviral therapy. Promoting access to therapy earlier in the course of the patient's disease, increasing the use

Contact: Richard Lane

Page: 1 2

Related medicine news :

1. Successful therapy for head and neck cancer may lead to long-term circulatory problems
2. Successful, rapid protein crystallization possible with technique developed by UCSD researcher
3. Successful prostate surgery: Its quality of surgery not quantity that matters most
4. Successful measles vaccination feasible in low-income countries
5. New Procedure Makes A Successful Transplant Possible
6. Patients Treated Successfully For Hodgkins Disease Are At 9 Times The Risk For Developing Second Cancer
7. Vaccine Against Melanoma Proves Successful For Patients With Disease Spread To Two Lymph Node Areas
8. NHLBI Clinical Trial Stopped Early: Successful Ventilator Strategy Found For Intensive Care Patients On Life Support
9. Magnetic Surgery System Tested Successfully On First Patient
10. Successful Atherosclerosis Treatment Program
11. DNA-Based Cancer Vaccine Shows Promise To Successfully Treat Melanoma In Mice

Post Your Comments:

(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: