HOME >> MEDICINE >> NEWS
Successful implementation of pilot study for HIV antiretroviral therapy in Uganda

Authors of a study in this week's issue of THE LANCET report on the successful implementation of a UNAIDS/Uganda Health Ministry initiative to provide antiretroviral treatment to people with HIV/AIDS in Uganda.

Little is known about how to implement complex HIV-1 treatment programmes in resource-limited countries. Paul Weidle from the Centers for Disease Control and Prevention, USA, and colleagues from Uganda assessed the UNAIDS/Uganda Ministry of Health HIV Drug Access Initiativeone of the first pilot antiretroviral programmes in Africain which patients paid for their medications at negotiated reduced prices.

912 patients were treated at five Ugandan centres; the investigators assessed the care of 476 patients at three centres, of whom 399 started antiretroviral therapy. Most patients accessed care at an advanced stage of HIV disease (median CD4 cell count 73 cells/mm3; viral load 193 817 copies/ml). Half the patients (51%) received highly active antiretroviral therapy (HAART), just under half (47%) received dual nucleoside reverse transcriptase inhibitors (2NRTIs), and 2% received a single NRTI.

An effective system for medical care and drug distribution was implemented resulting in an uninterrupted supply of drugs that supported sustainable management of patients. Patients returning for visits reported good adherence to treatment and achieved beneficial virologic and immunologic responses similar to those seen in more developed settings. The percentage of patients surviving and staying on therapy at six months was 63% and at one-year was 49%. Those with most advanced disease, a CD4 white blood cell count of less than 50 per microlitre of blood, were nearly three times as likely to die.

Paul Weidle comments: "This pilot programme showed that AIDS patients in a developing country can be managed successfully with antiretroviral therapy. Promoting access to therapy earlier in the course of the patient's disease, increasing the use
'"/>

Contact: Richard Lane
richard.lane@lancet.com
44-20-7424-4949
Lancet
4-Jul-2002


Page: 1 2

Related medicine news :

1. Successful therapy for head and neck cancer may lead to long-term circulatory problems
2. Successful, rapid protein crystallization possible with technique developed by UCSD researcher
3. Successful prostate surgery: Its quality of surgery not quantity that matters most
4. Successful measles vaccination feasible in low-income countries
5. New Procedure Makes A Successful Transplant Possible
6. Patients Treated Successfully For Hodgkins Disease Are At 9 Times The Risk For Developing Second Cancer
7. Vaccine Against Melanoma Proves Successful For Patients With Disease Spread To Two Lymph Node Areas
8. NHLBI Clinical Trial Stopped Early: Successful Ventilator Strategy Found For Intensive Care Patients On Life Support
9. Magnetic Surgery System Tested Successfully On First Patient
10. Successful Atherosclerosis Treatment Program
11. DNA-Based Cancer Vaccine Shows Promise To Successfully Treat Melanoma In Mice

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/15/2019)... ... August 15, 2019 , ... ... pathology residents who have been directly affected by the closure of Hahnemann University ... donations gathered during the campaign, the ASCP Foundation will be making hardship grants ...
(Date:8/14/2019)... ... 14, 2019 , ... Teguar Corporation has claimed the #3719 position on the ... established as a mark of success for some of Americas top companies and has ... list in 2015, 2016 and 2017. This year, Teguar secured a spot on the ...
(Date:8/14/2019)... ... ... New Hampshire-based Vera Roasting Company , makers of the only CBD coffee ... CBD-infused coffees with the release of a new higher-dosage organic Wellness Blend Coffee ... excited to expand our CBD-infused product lines to include a more potent CBD coffee ...
(Date:8/14/2019)... ... 14, 2019 , ... While it is commonly understood that good nutrition promotes ... can help them manage and, in some cases, reverse certain medical conditions, according to ... of U.S. adults are trying to manage a health or medical condition by making ...
(Date:8/12/2019)... ... August 12, 2019 , ... Parents craving a nutritious and delicious snack ... but also help feed children in need. IsaKids® Super Smoothie is one of three ... Tennessee. The global health and wellness company also debuted Organic Greens, an updated version ...
Breaking Medicine News(10 mins):
(Date:8/14/2019)... ... 14, 2019 , ... Bach Pharma, Inc., a company based ... platform GVT (Monosodium Luminol), created to treat and cure multiple neurodegenerative diseases including ... multiple animal studies have proven that GVT has the potential to help millions ...
(Date:8/14/2019)... ... August 14, 2019 , ... Canyon State Veterinary Specialties ... With pet care at the forefront of design, the project includes dedicated spaces ... Twelve exam rooms, office space and a dedicated grieving space round out this ...
(Date:8/14/2019)... ... August 13, 2019 , ... Ageless Innovation LLC, ... through the power of play, is proud to announce its Joy for All ... Awards. Today’s Caregiver, the first national magazine for all family and professional caregivers, ...
Breaking Medicine Technology:
Cached News: