Successful therapy for head and neck cancer may lead to long-term circulatory problems

Washington, DC Despite a steady stream of health advisories, younger Americans continue to light up in bars and restaurants. What many do not realize is that tobacco and alcohol combined contributes to head and neck cancer. While this is not one of the more common cancers, it is among the deadliest. Malignancies in this region of the body are among the most difficult to treat, resulting in a high mortality rate for these patients.

Specialists have found that a combination of chemotherapy and radiotherapy extends survival in patients with head and neck tumors. However, there is a downside to the treatment, especially radiotherapy. Cellular absorption of ionizing radiation generates toxic free radicals and leads to faulty repair of DNA breaks and cell death. Responses to radiotherapy occur in time frames of hours (nausea, vomiting), days (erythema), weeks (bone marrow supression), months (fibrosis), and years (carcinogenesis). Among survivors of the cancer itself, late effects on "bystander" organs -- such as the thyroid and salivary glands -- have become increasingly prevalent, with secondary malignancies and infections boosting the levels of sickness and death.

Physicians have noted that after neck irradiation, long-term injury commonly occurs in the carotid arteries. Atherosclerotic and thrombotic complications have drawn the most attention. For example, in a study of 910 patients who survived at least five years after irradiation of head and neck tumors, stroke occurred in about six percent and clinically significant carotid stenosis was observed in 17 percent.

A New Study

A new study examines three cases where symptomatic baroreflex failure occurred apparently as a late consequence of neck irradiation. The baroflex is originating from the stimulation of the carotid sinus baroreceptors and plays an important role in maintaining proper blood pressure.

Results Being Presented At Upcoming Conference


Contact: Donna Krupa
American Physiological Society

Page: 1 2 3 4

Related medicine news :

1. Successful, rapid protein crystallization possible with technique developed by UCSD researcher
2. Successful prostate surgery: Its quality of surgery not quantity that matters most
3. Successful implementation of pilot study for HIV antiretroviral therapy in Uganda
4. Successful measles vaccination feasible in low-income countries
5. New Procedure Makes A Successful Transplant Possible
6. Patients Treated Successfully For Hodgkins Disease Are At 9 Times The Risk For Developing Second Cancer
7. Vaccine Against Melanoma Proves Successful For Patients With Disease Spread To Two Lymph Node Areas
8. NHLBI Clinical Trial Stopped Early: Successful Ventilator Strategy Found For Intensive Care Patients On Life Support
9. Magnetic Surgery System Tested Successfully On First Patient
10. Successful Atherosclerosis Treatment Program
11. DNA-Based Cancer Vaccine Shows Promise To Successfully Treat Melanoma In Mice

Post Your Comments:

(Date:8/19/2019)... ... August 18, 2019 , ... ... launches its third product, Aqua+, adding two SKUs to its line of functional ... and more effectively than water alone. Distinguishing Aqua+ from other rehydration solutions is ...
(Date:8/16/2019)... ANGELES (PRWEB) , ... August 16, 2019 , ... ... to revolutionize and standardize pharmaceutical and non-pharmaceutical cannabidiol (CBD) products across the CBD ... is set to launch its crowdfunding campaign to raise $50 million on September ...
(Date:8/16/2019)... ANGELES (PRWEB) , ... August 16, 2019 , ... ... the Los Angeles market, has joined the esteemed Haute Beauty Network. , The ... Living is privileged to present Dr. Arnaoutakis as a hair restoration expert and ...
(Date:8/15/2019)... ... August 15, 2019 , ... Jon O'Brien, president of Catholics ... clinics to provide written assurance that they will comply with the Trump Administration’s ... Gag Rule, the new policy restricts providers and clinics that receive federal Title ...
(Date:8/14/2019)... LAUDERDALE, Fla. (PRWEB) , ... August 14, 2019 ... ... medical scribe and Care Team Assistant support, has earned a place on the ... this year’s Inc. 500|5000 inclusion marks nearly a decade of ScribeAmerica’s recognition as ...
Breaking Medicine News(10 mins):
(Date:8/16/2019)... CORDOVA, Calif. (PRWEB) , ... August 16, 2019 , ... ... growing company in the United States by Inc. magazine. MDstaffers three-year growth of ... have ranked it as the fastest growing human resources company had it competed in ...
(Date:8/16/2019)... ... 16, 2019 , ... Inc. magazine today revealed that Xavier ... prestigious ranking of the nation’s fastest-growing private companies. The list represents a unique ... independent small businesses. Microsoft, Dell, Domino’s Pizza, Pandora, Timberland, LinkedIn, Yelp, Zillow, and ...
(Date:8/15/2019)... ... August 15, 2019 , ... On Sunday, August 4th, volunteers from ... to make a difference in the South LA community. Six doctors joined with their ... , extractions , and more at the South Gate Day of Giving. ...
Breaking Medicine Technology:
Cached News: