Symptom improvement seen in schizophrenia patients switched to Risperdal Consta

21 September 2003 Prague People with schizophrenia and other psychiatric disorders can switch with ease from previous antipsychotic medications to RISPERDAL CONSTA (risperidone long acting injection), the first and only newer-generation, long-acting injectable antipsychotic. In chronic schizophrenia patients previously stabilised on various antipsychotic medications, symptom relief continues to improve in individuals who switched to Risperdal Consta. These are the key findings of research presented today at the 16th Congress of the European College of Neuropsychopharmacology (ECNP)1. In addition, unlike previous studies, patients were switched to Risperdal Consta without a supplementary run-in period with oral risperidone.

An estimated one percent of the world's population suffers from schizophrenia, a brain disorder that impairs a person's ability to think clearly, relate to others, and distinguish between reality and imagination. The illness is marked by "positive" symptoms (psychological disturbances "added" as a result of the disorder, such as hallucinations, delusions, suspiciousness and paranoia) and "negative" symptoms (normal functioning the patient has "lost," resulting in lack of initiative, social withdrawal, lack of expression and emotional withdrawal).

The pan-European "StoRMi" (Switch to Risperidone Microspheres) study is currently ongoing, and the first results reported are from a subgroup of the German participants. This open-label, multi-centre study found that patients previously treated with other antipsychotic medication could be switched safely and effectively to Risperdal Consta without a three-week period of "overlap treatment" with oral risperidone. Patients were continued on their previous antipsychotic medication for the first three weeks after the Risperdal Consta injections started, but no transition period with oral risperidone was required. Both positive and negative symptoms, as well as symptom severity and treatme

Contact: Roseann Ward
Resolute Communications

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