HOME >> MEDICINE >> NEWS
Synbiotic modulation of gut flora improves minimal hepatic encephalopathy in cirrhotic patients

Some cirrhotic patients develop brain dysfunction, called hepatic encephalopathy, which causes deficits in behavior, intelligence, consciousness and neuromuscular function. When the dysfunction is minor, it is called minimal hepatic encephalopathy (MHE). Since ammonia has been shown to play a key role in overt hepatic encephalopathy, treatment options for MHE have also focused on reducing ammonia levels in the body.

A new study published in the May 2004 issue of Hepatology has shown that treating cirrhotic patients with synbiotics or fermentable fiber can alter the flora in the gut, lowering its pH levels as well as the ammonia levels in the blood. Both treatments improved clinical signs of brain and liver dysfunction. They may be useful alternatives to lactulose for the management of MHE.

Hepatology, the official journal of the American Association for the Study of Liver Diseases (AASLD), published by John Wiley & Sons, Inc., is available online via Wiley InterScience at http://www.interscience.wiley.com/journal/hepatology.

To consider the effect of synbiotics and fermentable fiber on gut flora and MHE, a collaborative research team from Beijing Youan Hospital and Capital University of Medical Sciences, China, University College London, England and the Prince of Wales Hospital, Sydney, Australia conducted a pilot, placebo-controlled study of 55 individuals with MHE. Twenty of the patients were treated for 30 days with a daily symbiotic preparation. Twenty took fermentable fibers for 30 days, and fifteen received a placebo treatment for 30 days. At 30 days, all patients were re-screened for MHE. The researchers also assessed gut flora in fecal samples at day 1, day 30, and day 44. They compared their findings with the gut flora of 20 normal healthy volunteers.

After 30 days of treatment, 50 percent of patients treated with either the synbiotic preparation or ferment
'"/>

Contact: David Greenberg
dgreenbe@wiley.com
201-748-6484
John Wiley & Sons, Inc.
13-May-2004


Page: 1 2 3

Related medicine news :

1. Hormonal treatment improves survival in high-risk prostate cancer patients
2. Growth hormone treatment improves symptoms of metabolic disorder in postmenopausal women
3. New substance that improves the photodetection of bladder cancer gains market approval
4. Most advanced CT scanner improves imaging of heart, avoids need for surgical inspection
5. Columbia study finds hemophilia therapy dramatically improves outcomes for bleeding stroke
6. New test improves detection of bladder cancer
7. Adding radiation therapy to chemotherapy improves survival in patients with high-risk breast cancer
8. Care of rural stroke patients improves with telephone support
9. Acupuncture relieves pain and improves function in knee osteoarthritis
10. Daily social/physical activity improves sleep and cognition in the elderly
11. Stanford study finds new method improves chemotherapy survival in mice

Post Your Comments:
(Date:1/22/2015)... Deer Path of Huntley -- a BMA ... Hour from 3 p.m. to 4 p.m. on Feb. 13. , ... Illinois, serves adults with physical disabilities between the ages of 22 ... treats, games and sweetheart-themed karaoke. , For more information about the ...
(Date:1/22/2015)... PA (PRWEB) January 22, 2015 Woodloch Pines, ... Mountains, has been selected by TripAdvisor as the number one ... the 6th best in the world for their annual Travelers’ ... online travel community . The website is home to millions ...
(Date:1/22/2015)... 23, 2015 Angelweddingdress is a famous wedding ... its customers to follow it on Facebook, Twitter, and Pinterest. ... Day gift. Angelweddingdress draws a lottery every week. , Moreover, ... Feb. 28, 2015. Click Angelweddingdress homepage for more ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 A new ... of experience and person-centeredness in the long-term care environment ... action across the continuum. The paper, “The Power of ... engages perspectives and practices of the patient, resident and ...
(Date:1/22/2015)... Joan Lunden, award-winning American journalist, beloved ... upcoming 32nd Annual Miami Breast Cancer Conference ... LLC (PER®) , shares that “a fast-growing, virulent” cancer ... she had not followed up her clean mammogram with ...
Breaking Medicine News(10 mins):Health News:Deer Path of Huntley Affordable Assisted Living to Host Valentine's Day Happy Hour 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 3Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6
(Date:1/23/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/vzhr6h/video ) has ... Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - ... has been the topic of fascination since the era of ... and the Soviet Russia. Earlier even a small glimpse ...
(Date:1/23/2015)... analysis of Centers for Medicare and Medicaid Services, (CMS) ... percent of seniors chose lower-cost preferred pharmacy plans that ... The findings were released by Drug Channels . ... of Medicare Part D," said Pharmaceutical Care Management Association ...
(Date:1/23/2015)... DUBLIN , Jan. 23, 2015  Immune Therapeutics, Inc. today ... Inc. for the compounding, packaging and distributing of its naltrexone ... the United States . KRS ... compounding naltrexone tablets in various strengths for individual patients in ...
Breaking Medicine Technology:Video Telemedicine Market- Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Video Telemedicine Market- Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3New Analysis: 81 Percent of Medicare Part D Seniors Choose "Preferred Pharmacy" Plans in 2015 2Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 2Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 3Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 4
Cached News: