HOME >> MEDICINE >> NEWS
Taking painkillers during pregnancy increases risk of miscarriage

Women who take non-steroidal anti-inflammatory drugs (NSAIDs) or aspirin during pregnancy increase their risk of miscarriage by 80 per cent, finds a study in this week's BMJ.

Researchers in California interviewed 1,055 pregnant women immediately after their pregnancy was confirmed. They asked the women about their drug use since they became pregnant, their reproductive history, known or potential risk factors for miscarriage, and sociodemographic characteristics.

They found that use of NSAIDs during pregnancy increased the risk of miscarriage by 80%. The risk was much higher when NSAIDs were taken around conception or were used for longer than a week. Taking account of other factors, including drinking alcohol or coffee, did not change the results.

Aspirin was similarly associated with an increased risk of miscarriage but paracetamol was not, regardless of timing and duration of use.

All three drugs work by suppressing the production of prostaglandins (fatty acids needed for successful implantation of an embryo in the womb). Because NSAIDs and aspirin act on the whole body, they could lead to abnormal implantation that predisposes an embryo to miscarriage. In contrast, paracetamol acts only in the central nervous system, which may explain why it has no effect on risk of miscarriage, explain the authors.

These findings will need confirmation, say the authors. Meanwhile, it may be prudent for physicians and women who are planning to be pregnant to be aware of this potential risk and avoid using NSAIDs around conception.


'"/>

Contact: Emma Dickinson
edickinson@bmj.com
44-0-207-383-6529
BMJ-British Medical Journal
14-Aug-2003


Page: 1

Related medicine news :

1. Taking a number of medications regularly could give you a serious headache
2. Taking pills, even if placebo, predicts better survival in heart failure
3. Taking apart a hurricane: Multi-sensor Envisat sees through Frances
4. Taking vitamins to lower amino acid level in blood does not reduce the risk of recurrent stroke
5. Taking vitamin D supplements lowers risk of multiple sclerosis
6. Taking Ecstasy during pregnancy may cause brain damage, behavior problems in babies
7. Taking control: Lab testing you order for yourself
8. Taking public health to the streets works
9. Adolescents And Risk-Taking: A Very Likely Danger May Not Mean The Same To A Teen As To An Adult
10. Medical Students Are Taking Risks With HIV During Elective Studies
11. Infants To Seniors: Seven Years Follow-Up Of 1,000 Liver Transplant Patients Taking Tacrolimus Indicates Children Have Best Survival

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... 13, 2017 , ... Many families have long-term insurance that covers care for ... a waiver for care if the client has a cognitive impairment diagnosis. , ... care, is often waived, so the benefits from their insurance start immediately,” said Mechell ...
(Date:10/13/2017)... ... , ... Talented host, actor Rob Lowe, is introducing a ... episode of "Success Files," which is an award-winning educational program broadcasted on PBS ... in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve in ...
(Date:10/12/2017)... ... 12, 2017 , ... CitiDent and San Francisco dentists, Dr. ... Oventus O2Vent technology. As many as 18 million Americans are estimated to suffer ... Oral appliances can offer significant relief to about 75 percent of people with ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... a leader in post-acute health care, have expanded their existing home health joint ... Health. , AccentCare has been operating a joint venture home health company with ...
(Date:10/12/2017)... ... October 12, 2017 , ... On Saturday, October 21, the Health & ... by Moonlight to raise money for the American Heart Association Heart Walk. Teams of ... will work together to keep their treadmills moving for 5 hours. Treadmills will start ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... -- Caris Life Sciences ® , a leading innovator in ... medicine, today announced that St. Jude Medical Center,s Crosson ... as its 17 th member. Through participation with ... Institute will help develop standards of care and best ... cancer treatment more precise and effective. ...
(Date:10/10/2017)... , Oct. 10, 2017  NDS received FDA 510(k) clearance in ... medical-grade battery-powered display stand specifically designed for endoscopy environments. An innovative ... into a clinical solution to support the improvement of patient outcomes, ... Design ... Solution ...
(Date:10/5/2017)... 2017  In response to the nationwide opioid ... Surgeons (AAOMS) released prescribing recommendations that urge ibuprofen ... as a first-line therapy to manage a patient,s ... Recognizing the value and importance of ... Prescribing: Acute and Postoperative Pain Management" stresses that ...
Breaking Medicine Technology:
Cached News: