HOME >> MEDICINE >> NEWS
Targeted antiviral prophylaxis of flu case contacts could successfully contain pandemic influenza

ATLANTA In a future outbreak of pandemic influenza, such as the three pandemics that sickened millions and killed hundreds of thousands of people during the 20th century, supplies of flu vaccine might not be available quickly enough to contain the spread of disease. However, according to research by biostatisticians in Emory University's Rollins School of Public Health, many thousands of deaths could be prevented if antiviral agents were given to the close contacts of those with suspected cases of flu until adequate supplies of vaccine could be manufactured and distributed. The results of the research by Emory professors of biostatistics Ira Longini, Jr,, PhD, and M. Elizabeth Halloran, MD, DSc, and their colleagues Azhar Nizam, MS, and Yang Yang, BSc, will appear online on March 26, and will be published as a special article in the American Journal of Epidemiology on April 1, 2004.

The Emory scientists used a dynamic stochastic simulation model of an influenza pandemic or bioterrorist attack for an agent similar to influenza A(H2N2), which caused the Asian influenza pandemic of 1957-58 and resulted in approximately 70,000 deaths in the U.S. (A stochastic model includes elements of chance or probability). They determined that if no interventions were used in a similar pandemic, 33 percent of the population would become ill, resulting in a death rate of 0.58 per 1,000 people. If antiviral prophylaxis was given to close contacts of 80% of suspected influenza cases, however, in a strategy that the authors call "targeted antiviral prophylaxis" (TAP), the epidemic could be contained. If TAP were begun within one day of identifying suspected flu cases and used for up to eight weeks, only 2 percent of the population would become ill, and the death rate would be only 0.04 per 1,000 people. The researchers found that eight weeks of TAP would be nearly as effective as vaccinating 80 percent of the population.

"The ability to rely on targeted antiviral t
'"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University Health Sciences Center
1-Mar-2004


Page: 1 2 3 4

Related medicine news :

1. Smallpox outbreak response: Targeted vaccination may be almost as effective as mass vaccination
2. Targeted smallpox vaccinations could be effective intervention against deliberate attack
3. Targeted toxins may revolutionize pain therapy
4. Breakthrough New Therapy Uses Antibody-Targeted Chemotherapy To Fight Leukemia
5. Fred Hutchinson Cancer Research Center And Targeted Genetics Corp. Publish Data On Adoptive Immunotherapy For HIV
6. Promising New Drug Uses Antibody Targeted Chemotherapy To Fight Leukemia
7. Targeted Protein Toxin Effective Against Persistent Brain Tumors
8. Use of antivirals by HIV-infected persons reduced their ability to infect partners
9. UCSF begins study testing antiviral drug tenofovir to prevent HIV infection
10. Stanford researchers study new antiviral approach to protect women from HIV
11. ICAAC highlight: MAC prophylaxis can be safely discontinued in HIV-infected patients who respond to HAART

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... August 31, 2020 , ... Genesis Chiropractic Software and ... the launch of its integrated, HIPAA compliant, telehealth solution, available to US-based clients ... under 90 seconds. , According to the U.S. Department of Health & ...
(Date:8/31/2020)... ... 31, 2020 , ... Smile Brands Inc., one of the ... States, today announced the grand opening of another affiliated Bright Now! Dental ... convenient hours, a comfortable office, and full-service care at the new Beaumont location. ...
(Date:8/31/2020)... ... ... “PTS” with Mediation & Hypnosis , At this very turbulent time in the world, ... immense stress, and right now are needing serious relief from a constant state of endless ... experiencing a great degree of emotional discomfort, be it fear or worrying about their income ...
(Date:8/31/2020)... ... August 31, 2020 , ... Dr. ... with persons with autism and other developmental disabilities, as well as supporting staff ... education, adolescents with autism, school consultation, and staff development. She joined the company ...
(Date:8/29/2020)... ... August 29, 2020 , ... When professor and author Randy Pausch was ... most people would. Rather than become melancholic, however, he put together a final lecture ... dreams. Randy Pausch took a negative situation and turned it into something that inspired ...
Breaking Medicine News(10 mins):
(Date:8/28/2020)... ... ... Dr. Mark Surrey has been in practice for over 25 years. He ... the Department of OBGYN at UCLA’s David Geffen School of Medicine. , He ... is a Clinical Director of Fellowship Training for UCLA & Cedars Sinai Reproductive Endocrinology. ...
(Date:8/27/2020)... FLINT, Mich. (PRWEB) , ... August 27, 2020 , ... The flu season is right ... need to get well equipped with all the necessary measures before it begins to harbor ... is also increasing, and it is leaving a huge impact on our lives. Hence it ...
(Date:8/27/2020)... VISTA, Calif. (PRWEB) , ... August 27, 2020 , ... ... celebrate the conclusion of its fundraising initiative for Feeding San Diego with ... , What: The GHT Companies presents the final check of $5,000.00+ representing an overall ...
Breaking Medicine Technology:
Cached News: