HOME >> MEDICINE >> NEWS
The impact of body weight on the progression of knee osteoarthritis

A painful and sometimes crippling disease characterized by progressive cartilage loss, osteoarthritis (OA) of the knee affects an estimated 6 percent of adults over age 30. AT present, no treatments are available that have been shown to impede the destructive course of this disease, apart from knee replacement surgery. Numerous studies have shown that being overweight increases the risk of developing knee OA, whose sufferers, on average, tend to be heavy. While doctors routinely advise patients to lose weight, researchers have yet to affirm the benefits of weight loss to prevent ongoing joint deterioration.

To better understand the effect of body weight on the course of knee OA, researchers at Boston University focused on an important predictor of disease progression: limb malalignment, defined by joint space loss at the point where the thigh and shin bones connect to the knee. Featured in the December 2004 issue of Arthritis & Rheumatism (http://www.interscience.wiley.com/journal/arthritis), their findings suggest that the benefits of weight loss for knee OA patients depend on the degree of alignment in the affected leg.

The researchers recruited their subjects from two studies on quality of life conducted by the Veterans Administration of the Boston Health Care System. 228 individuals with knee OA were selected; all but one completed a 30-month period of follow-up. 41 percent were women and the mean age was 66 years. Among the subjects, the diagnosis of OA was confirmed by radiographs in 394 knees. At the first follow-up examination, each subject was assessed for degree of alignment in the affected leg, which was then categorized as moderate, severe, or neutral. Malaligned limbs could be either varus (bowlegged) or valgus (knock-kneed). The body mass index (BMI) of each subject was also computed.

Of the tota
'"/>

Contact: Amy Molnar
amolnar@wiley.com
John Wiley & Sons, Inc.
2-Dec-2004


Page: 1 2

Related medicine news :

1. Cockroach allergens have greatest impact on childhood asthma in many US cities
2. The impact of cruciate ligament rupture on osteoarthritis of the knee
3. Folic acid recommendations have had little impact on birth defects
4. Flu vaccination impact on elderly deaths may be over-estimated
5. Study suggests obesity has lesser financial impact on African-Americans
6. Study models impact of anthrax vaccine
7. Study examines impact of two-year screening interval for breast cancer
8. Study clarifies impact of age on safety of warfarin treatment for atrial fibrillation
9. Exercise for special populations, sensory research, factors impacting rehabilitation top issues
10. PITT, OHSU: When early life stress occurs determines its impact later
11. Scientists reveal significant behavioral impacts of early life stress, study therapies

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: The impact body weight the progression knee osteoarthritis

(Date:4/18/2014)... School of Medicine researchers have been awarded two-year grants ... Nordisk announced this month. Of the 110 initial submissions ... Science Forum Program, only four projects were funded, three ... are Jonathan Powell, M.D., Ph.D.; G. William Wong, Ph.D.; ... a professor of oncology, will use his $500,000 proof ...
(Date:4/18/2014)... Fraser University psychologists have made a brain-related discovery ... attention-deficit disorders. , This discovery opens up the ... or suppress a specific brain activity that the ... , The Journal of Neuroscience has ... John McDonald, an associate professor of psychology and ...
(Date:4/18/2014)... A discovery by Northwestern Medicine scientists could lead to ... scarring in people with scleroderma. , Fibrosis, or ... tightening of the skin and lungs can lead to ... The concept for new therapeutic options centers on findings ... Medicine-Rheumatology, who identified the role that a specific protein ...
(Date:4/17/2014)... Scientists have identified the first genetic variant specifically ... sub-type accounting for around 10-15 per cent of ... study of the breast cancer sub-type, called invasive ... genetic causes of this particular kind of breast ... The research, published today (Thursday) in the journal ...
(Date:4/17/2014)... According to a study published today in PLOS ... world where malaria is common can mount an immune ... them to avoid repeated bouts of high fever and ... in their bloodstream. The findings may help researchers develop ... by the malaria parasite. , Each year, approximately 200 ...
Breaking Medicine News(10 mins):Health News:Scientists discover brain's anti-distraction system 2Health News:New clues on tissue scarring in scleroderma 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 3Health News:Study sheds light on how the immune system protects children from malaria 2
(Date:1/14/2014)... Calif. , Jan. 14, 2014 The Brandeis Medical Center, ... Angeles a premier and affordable laser tattoo removal experience ... Dr. Brandeis, focus is in providing high quality cosmetic services with ... patients. " Southern California has seen ...
(Date:1/14/2014)... Emergency Critical Care, a LifeCentre partner practice, located at 165 Fort ... first in Loudoun County to receive a ... M. Barnes , Medical Director, is a well-seasoned veterinarian of more ... , are avid scuba divers. "As altitude skiers and hikers, we ...
(Date:1/14/2014)... Oligomerix, Inc. , a privately held company pioneering the ... and related neurodegenerative disorders, announced today the relocation of ... as of January 15, 2014 and expanded lease ... College. Oligomerix, which is focused on the ...
Breaking Medicine Technology:Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2Hyperbaric Veterinary Medicine (hvm) Announces Animal Emergency Critical Care Installs A Small Animal Hyperbaric Chamber 2Oligomerix Relocates Corporate Headquarters and Secures Additional Laboratory Space from New York Medical College 2
Cached News: