HOME >> MEDICINE >> NEWS
The impact of body weight on the progression of knee osteoarthritis

A painful and sometimes crippling disease characterized by progressive cartilage loss, osteoarthritis (OA) of the knee affects an estimated 6 percent of adults over age 30. AT present, no treatments are available that have been shown to impede the destructive course of this disease, apart from knee replacement surgery. Numerous studies have shown that being overweight increases the risk of developing knee OA, whose sufferers, on average, tend to be heavy. While doctors routinely advise patients to lose weight, researchers have yet to affirm the benefits of weight loss to prevent ongoing joint deterioration.

To better understand the effect of body weight on the course of knee OA, researchers at Boston University focused on an important predictor of disease progression: limb malalignment, defined by joint space loss at the point where the thigh and shin bones connect to the knee. Featured in the December 2004 issue of Arthritis & Rheumatism (http://www.interscience.wiley.com/journal/arthritis), their findings suggest that the benefits of weight loss for knee OA patients depend on the degree of alignment in the affected leg.

The researchers recruited their subjects from two studies on quality of life conducted by the Veterans Administration of the Boston Health Care System. 228 individuals with knee OA were selected; all but one completed a 30-month period of follow-up. 41 percent were women and the mean age was 66 years. Among the subjects, the diagnosis of OA was confirmed by radiographs in 394 knees. At the first follow-up examination, each subject was assessed for degree of alignment in the affected leg, which was then categorized as moderate, severe, or neutral. Malaligned limbs could be either varus (bowlegged) or valgus (knock-kneed). The body mass index (BMI) of each subject was also computed.

Of the tota
'"/>

Contact: Amy Molnar
amolnar@wiley.com
John Wiley & Sons, Inc.
2-Dec-2004


Page: 1 2

Related medicine news :

1. Cockroach allergens have greatest impact on childhood asthma in many US cities
2. The impact of cruciate ligament rupture on osteoarthritis of the knee
3. Folic acid recommendations have had little impact on birth defects
4. Flu vaccination impact on elderly deaths may be over-estimated
5. Study suggests obesity has lesser financial impact on African-Americans
6. Study models impact of anthrax vaccine
7. Study examines impact of two-year screening interval for breast cancer
8. Study clarifies impact of age on safety of warfarin treatment for atrial fibrillation
9. Exercise for special populations, sensory research, factors impacting rehabilitation top issues
10. PITT, OHSU: When early life stress occurs determines its impact later
11. Scientists reveal significant behavioral impacts of early life stress, study therapies

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/24/2017)... ... , ... An in-depth computational analysis of genetic variants implicated in both schizophrenia ... that may explain why susceptibility to one of the disorders could place individuals at ... in the journal npj Schizophrenia. , “There is a wealth of genomic data ...
(Date:2/24/2017)... ... ... With millions of Americans and people worldwide struggling with ... aware of our options and are empowered with strength and information throughout the ... newest edition of "Vision and Hearing" in USA Today, that will educate readers ...
(Date:2/24/2017)... ... February 24, 2017 , ... The California State University Institute for ... engaged in or interested in palliative care education and research. The Symposium, “Innovate. ... North County San Diego on Sept. 28 and 29, 2017, on the campus of ...
(Date:2/24/2017)... ... February 24, 2017 , ... The Radiology Business ... in radiology marketing programs at the annual Building Better Radiology Marketing Programs ... Worth Hotel in Fort Worth, Texas. Nine awards are given out in five categories. ...
(Date:2/23/2017)... Austin, TX (PRWEB) , ... February 23, 2017 ... ... has announced an official 2017 partnership with The Jensie Gran Fondo of Marin. ... UVA and UVB rays with Thinksport’s broad-spectrum, mineral-based sunscreen. , “We are thrilled ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... 24, 2017 Medivir AB (Nasdaq ... a new Board of Directors that will be submitted ... Committee comprises representatives of the company,s three largest shareholders ... who have accepted a seat on the Nomination Committee, ... the 2016-2017 Nomination Committee was as follows:  ...
(Date:2/23/2017)... Feb 23, 2017 Research and Markets has ... Analysis and Strategies - 2016" report to their offering. ... The latest research ... drug pricing data and benchmarks in the global Autism Spectrum Disorder ... What are the key drugs marketed for Autism Spectrum ...
(Date:2/23/2017)... Australia , Feb. 23, 2017 ITL Limited, ( ... announce excellent results for the half year ended 31 December 2016 ... BioMedical Growth Update" presentation can be viewed here . ... $2.12m (Dec 2015: $1.04m; up 104%) Earnings per ... Revenue of $17.5m (Dec 2015: $15.7m; up 11%) ...
Breaking Medicine Technology:
Cached News: