HOME >> MEDICINE >> NEWS
Three-month antibiotic treatment reduces risk of future heart attack

DALLAS, March 12 An antibiotic prolonged life and reduced risk of future heart attacks in people hospitalized for heart attack or unstable angina, according to a report in todays rapid access issue of Circulation: Journal of the American Heart Association.

The antibiotic clarithromycin significantly lowered risk of death or serious cardiovascular events compared to those given a placebo. Clarithromycin is typically prescribed for respiratory infections.

Patients with acute heart attacks or severe angina seem to benefit from treatment with a macrolide antibiotic, says lead author Juha Sinisalo, M.D., of Helsinki University Central Hospital in Helsinki, Finland. The most likely mechanism of action is clarithromycins antibacterial effect.

Infections are one cause of inflammation, and inflammation plays an important role in the development of coronary heart disease. Increasing evidence from animal and human studies indicates that several infections such as Chlamydia pneumoniae are associated with coronary heart disease.

Although the apparent advantage of clarithromycin likely stems from its antibacterial power, the drug may do double duty in coronary heart disease patients. Clarithromycin also has an anti-inflammatory action that is independent of its effect on bacteria, he says.

There are only two ways to prove the connection between infections and coronary artery disease: vaccinations and antibiotic therapy, says Sinisalo. Vaccinations to prevent heart disease are not available. Therefore, we conducted this study to find out if suppressing infections would decrease the rate of new heart attacks.

Researchers have published results from only a few studies that have tested antibiotics for patients with a high risk of heart attack. Trials in patients with stable heart disease have yielded differing results. In a previous randomized study, a macrolide antibiotic was used for one month to treat people with acute coronary problems.
'"/>

Contact: Carole Bullock
carole.bullock@heart.org
214-706-1279
American Heart Association
11-Mar-2002


Page: 1 2 3

Related medicine news :

1. Invasive pneumonia and antibiotic resistance decreased after childhood vaccine introduced
2. Study examines three-day antibiotic regimens for treating bladder infection in women
3. Immediate access to antibiotics stems spread of sexually transmitted diseases
4. Over prescribing causing high rates of antibiotic resistance in south and east Europe
5. Middle ear infections: Prescribe antibiotics or not?
6. Study explores antibiotic misuse
7. OTC treatment for acne as good as antibiotics
8. Novel antibiotic shows promise in shortening treatment duration of tuberculosis
9. African children with HIV would benefit from daily doses of cheap antibiotic
10. Some antibiotic resistance threat in hospitals could yield to hand washing
11. Patients with chronic sinus do not necessarily develop antibiotic resistance

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... ... Arkansas that offers insurance and financial preparation services, is providing an update on ... Rescue organization. , Rock City Rescue is a locally recognized nonprofit that provides ...
(Date:10/13/2017)... Nevada (PRWEB) , ... October 13, 2017 , ... ... Hemp CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil ... required and providing a CBD form that can be easily incorporated into liquid products, ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) ... a collection of specialty vendors and unique items from across the nation, this holiday-themed ... and wellness services offered by the VNA. The boutique will be open Saturday, ...
(Date:10/13/2017)... ... 13, 2017 , ... Coveros, a leader in agile coaching ... contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise Agile ... of Agile methodologies in a consistent and high value manner across CMS programs. ...
(Date:10/12/2017)... ... 2017 , ... Planet Fitness, one of the largest and fastest growing franchisors ... a flagship location in Covington, LA at 401 N. U.S. Highway 190, in January ... Office Depot in the Holiday Square shopping center. Its location allows it to serve ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... , Sept. 27, 2017  Commended for their devotion to ... awards. Ranked as number one in the South Florida Business ... in Inc. 5000 yearly list, the national specialty pharmacy has ... Armando Bardisa will soon be honored by SFBJ as ... Set to receive his award in October, ...
(Date:9/22/2017)... Md. , Sept. 22, 2017  As the ... Republican Senators Bill Cassidy (R-LA) and ... Information notes that the medical device industry is in ... medical device tax, the 2.3% excise tax on medical ... But they also want covered patients, increased visits and ...
(Date:9/18/2017)... Sept. 18, 2017 EpiVax, Inc. ... bioinformatics and immune engineering, today announced a ... A (H7N9) vaccine. ... seasonal influenza and presents a challenge for ... exposure to be effective. Using state-of-the-art bioinformatics and ...
Breaking Medicine Technology:
Cached News: