HOME >> MEDICINE >> NEWS
Tiny nerves from the ribs may restore leg movement in spinal cord injury

Irvine, Calif. -- Paralysis from spinal cord injury was significantly reversed by adding tiny nerves from the rib cage and mixing them with a powerful growth inducer found in most nerve cells, a UC Irvine and Long Beach Veterans Administration Medical Center study has found.

The study, conducted in rats, suggests that nerve cells can be inserted and stimulated to grow through damaged areas of the spinal cord, perhaps leading to better treatments for spinal cord injury. The research is part of a wave of studies challenging the conventional wisdom that severed nerves in the spinal cord are nearly impossible to regenerate. The study appears in the October issue of the Journal of Neurotrauma.

Dr. Vernon Lin, professor of physical medicine at UCI and director of the Spinal Cord Injury Group at the Long Beach V.A., and his colleagues found that grafting nerves from the rib cage and adding the growth stimulator, a molecule called aFGF, partially restored hind leg movement in rats that had their spinal cords severed.

"By using tiny nerves from the rib cage as cables connecting the severed spinal cord, we were able to get some improvement in leg function," Lin said. "Regeneration is considered very difficult because the damaged area apparently inhibits growth of new nerve-cell connections. This study gets us closer to arriving at the right combination of growth factors, nerve cells and physical stimulation that overcome these inhibitions and successfully treat spinal cord injury."

Lin and his team found that 12 rats with severed spinal cords were able to move their hind legs again after treatment with both the aFGF and the nerve grafts, while rats that had either the aFGF or nerve grafts alone showed nearly no improvement. Rats receiving both the growth factor and the nerve cell grafts could support some of their weight on their back legs.

The growth factor aFGF is normally produced in the spinal cord by nerve cells, but scientists s
'"/>

Contact: Andrew Porterfield
amporter@uci.edu
949-824-3969
University of California - Irvine
5-Oct-2002


Page: 1 2

Related medicine news :

1. Antibiotics protect nerves in mice by turning on genes
2. Reduced scarring helps nerves grow through spinal injuries
3. Acupuncture calms nerves, improves heart function
4. New plastic heals damaged nerves
5. Cartilage repair techniques shown to restore patient mobility and reduce pain
6. Rehabilitation can restore some vision after stroke
7. Fetal tissue restores lost sight
8. Faith in child protection system must be restored
9. Botox injections restore voices, confidence to voice disorder patients
10. Mayo Clinic researchers restore lost immunity -- Possible breakthrough for AIDS
11. Disc replacement in neck relieves pain, restores mobility

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/8/2018)... ... December 07, 2018 , ... “The Better World Campaign congratulates ... U.S. leadership and funding at the United Nations matters. We have seen the ... poverty and advancing global health plus meaningful reforms in development, management, and peacekeeping ...
(Date:12/6/2018)... , ... December 06, 2018 , ... ... the tropical disease schistosomiasis significantly faster than the drug most commonly used against ... the Democratic Republic of Congo. The study’s authors, including a professor and two ...
(Date:12/5/2018)... ... December 05, 2018 , ... Adam Devlin , ... reappointed to serve on Philadelphia Mayor James F. Kenney’s Commission on People with ... identify with a cognitive or physical disability. Devlin serves as the chair of ...
(Date:12/5/2018)... ... 05, 2018 , ... A well-known name in the world of gyms and ... Wellbeats , which has delivered on-demand, virtual fitness programming to employers, gyms and fitness ... now in the Apple App Store, the Wellbeats app is fitness that fits for ...
(Date:12/5/2018)... ... December 05, 2018 , ... Since PermaLip™ implants are solid, patients ... to the naked eye, ensuring a natural look. “I always double and triple check ... signs of implant visibility,” says Dr. Jessica Kulak, double board certified facial plastic surgeon ...
Breaking Medicine News(10 mins):
(Date:12/6/2018)... , ... December 06, 2018 , ... Last year, 172 ... officials, 80% of those children had not gotten the vaccine. Vaccination is the first ... as flu shots reduce the severity of the illness if infected. Along with getting ...
(Date:12/6/2018)... ... December 06, 2018 , ... Every day, and especially ... towels are the best way to clean up (and throw away) bacteria-filled messes, and ... before they’re washed, which can spread germs around other kitchen surfaces and increase the ...
(Date:12/5/2018)... ... December 05, 2018 , ... Trivellini Tech announces the latest ... based on a version previously known as Mamba Nano, Trivellini Long Hair introduces the ... this version of “Trivellini system has the same capabilities as the last generation but ...
Breaking Medicine Technology:
Cached News: