HOME >> MEDICINE >> NEWS
Tissue involved in brain development may offer new approach to stroke treatment

The same tissue that helps a developing brain form its protective blood-brain barrier may protect the adult brain from the ravages of stroke, researchers say.

The choroid plexus has been relegated as a bystander in the adult brain, says Dr. Cesario V. Borlongan, neuroscientist at the Medical College of Georgia and first author on a study published in the May issue of NeuroReport.

But within the last five years, researchers across the world have been compiling evidence that in response to stroke as well as other brain injury or disease, the tissue may actually stimulate the production of stem cells that could help replace damaged neurons and neurotrophic factors that nourish brain cells, Dr. Borlongan says.

This latest study is the first to show the therapeutic potential of that natural response: when biocompatible microcapsules containing these choroid plexus cells were placed on top of the brains of animal models for stroke, stroke damage was significantly reduced.

"The transplanted choroid plexus may provide a potential new therapy to reduce and repair damage from stroke," Dr. Borlongan says. However, he noted that much work remains to explore the potential, including whether the findings in animal models hold true for humans and the best way to deliver that protection.

"We found that these animals that got transplanted choroid plexus had very small stroke areas," Dr. Borlongan says. "This is the first indication that choroid plexus is important tissue for the formation of new stem cells and/or secretion of trophic factors."

The findings also are being presented at the 11th annual meeting of the American Society for Neural Transplantation and Repair May 6-9 in Clearwater Beach, Fla.

For his studies, Dr. Borlongan used choroid plexus cells taken from a rat or pig and placed inside tiny capsules designed by LCTBioPharma, Inc., in Providence, R.I., a subsidiary of Living Cell Technologies based in New Zealand an
'"/>

Contact: Toni Baker
tbaker@mcg.edu
706-721-4421
Medical College of Georgia
6-May-2004


Page: 1 2 3

Related medicine news :

1. Tissue-engineered valves give diseased hearts new life
2. Tissue-engineered cells transmit electrical signals in animal hearts
3. Tissue engineers steering stem cells to produce bone, cartilage
4. Tissue engineering could become new coronary bypass
5. Maternal Tissue Typing Could Improve Selection Of Kidney Transplant Donors
6. Researchers identify cancer-causing gene involved in aggressive leukemia, lymphoma
7. Hebrew University one of 25 institutions involved in new European Vascular Genomics Network
8. OHSU researchers uncover genes involved in early stages of Alzheimers disease
9. Unsuspected brain region involved in side effects of diabetes drugs
10. Rutgers scientists pinpoint brain cells involved in drug addiction relapse
11. Mouse studies reveal immune mechanism involved in bone loss caused by estrogen deficiency

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/2/2018)... ... August 02, 2018 , ... Mindray, ... 7 Ultrasound system with unique new upgrades at the Society of Vascular Ultrasound ... ZONE Sonography® Technology (ZST), the upgrades include a unique arterial stiffness measurement, which ...
(Date:8/2/2018)... ... August 02, 2018 , ... A new ... topics in acute pain management. In The Role of Acute Care in the ... Engagement Network—an innovative approach to the opioid epidemic launched in the state of ...
(Date:8/2/2018)... ... August 01, 2018 , ... Continuing their momentum in 2018 Sempulse has ... and Chief Investment Officer of Ecliptic Capital, Mike W. Erwin, an early investor in ... have lived in Austin for over 30 years starting companies and investing locally. The ...
(Date:8/2/2018)... MORRISTOWN, N.J. (PRWEB) , ... ... ... Wittig, MD, Orthopedic Oncologist and Sarcoma Surgeon, has been appointed Chairman of ... Orthopedic Oncology at Atlantic Health System, commencing August 1, 2018. ...
(Date:8/1/2018)... and LOS ANGELES (PRWEB) , ... August 01, 2018 , ... ... (MMA) Athlete and two-time UFC Bantamweight Champion TJ Dillashaw have forged a partnership. ... is on the FORBES Top 10 List of CBD Hemp Brands in the country, ...
Breaking Medicine News(10 mins):
(Date:8/9/2018)... ... 2018 , ... Cannabidiol, or CBD, has grabbed national headlines in recent months ... precisely why National Day Calendar collaborated with cbdMD to create a holiday in support ... of National CBD Day after weeks of tireless planning in an effort to bring ...
(Date:8/7/2018)... , ... August 06, 2018 , ... ... gum disease in Clinton, MS using laser dentistry techniques. Using their BIOLASE ... cutting-edge laser gum therapy called REPAIR Perio™. , Affecting the lives of millions ...
(Date:8/7/2018)... ... August 07, 2018 , ... Braun Ambulances is honored to announce ... Bailey Hutchison Convention Center in Dallas, Texas. Braun Ambulances will have four units on ... model. , Fire Rescue International (FRI) is the International Association of Fire Chiefs’ ...
Breaking Medicine Technology:
Cached News: