HOME >> MEDICINE >> NEWS
Tissue involved in brain development may offer new approach to stroke treatment

The same tissue that helps a developing brain form its protective blood-brain barrier may protect the adult brain from the ravages of stroke, researchers say.

The choroid plexus has been relegated as a bystander in the adult brain, says Dr. Cesario V. Borlongan, neuroscientist at the Medical College of Georgia and first author on a study published in the May issue of NeuroReport.

But within the last five years, researchers across the world have been compiling evidence that in response to stroke as well as other brain injury or disease, the tissue may actually stimulate the production of stem cells that could help replace damaged neurons and neurotrophic factors that nourish brain cells, Dr. Borlongan says.

This latest study is the first to show the therapeutic potential of that natural response: when biocompatible microcapsules containing these choroid plexus cells were placed on top of the brains of animal models for stroke, stroke damage was significantly reduced.

"The transplanted choroid plexus may provide a potential new therapy to reduce and repair damage from stroke," Dr. Borlongan says. However, he noted that much work remains to explore the potential, including whether the findings in animal models hold true for humans and the best way to deliver that protection.

"We found that these animals that got transplanted choroid plexus had very small stroke areas," Dr. Borlongan says. "This is the first indication that choroid plexus is important tissue for the formation of new stem cells and/or secretion of trophic factors."

The findings also are being presented at the 11th annual meeting of the American Society for Neural Transplantation and Repair May 6-9 in Clearwater Beach, Fla.

For his studies, Dr. Borlongan used choroid plexus cells taken from a rat or pig and placed inside tiny capsules designed by LCTBioPharma, Inc., in Providence, R.I., a subsidiary of Living Cell Technologies based in New Zealand an
'"/>

Contact: Toni Baker
tbaker@mcg.edu
706-721-4421
Medical College of Georgia
6-May-2004


Page: 1 2 3

Related medicine news :

1. Tissue-engineered valves give diseased hearts new life
2. Tissue-engineered cells transmit electrical signals in animal hearts
3. Tissue engineers steering stem cells to produce bone, cartilage
4. Tissue engineering could become new coronary bypass
5. Maternal Tissue Typing Could Improve Selection Of Kidney Transplant Donors
6. Researchers identify cancer-causing gene involved in aggressive leukemia, lymphoma
7. Hebrew University one of 25 institutions involved in new European Vascular Genomics Network
8. OHSU researchers uncover genes involved in early stages of Alzheimers disease
9. Unsuspected brain region involved in side effects of diabetes drugs
10. Rutgers scientists pinpoint brain cells involved in drug addiction relapse
11. Mouse studies reveal immune mechanism involved in bone loss caused by estrogen deficiency

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... ... viewers the lowdown on sciatica in a new episode of "Success Files," which ... current events and innovation and investigates each subject in-depth with passion and integrity. ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... “America On ... Christian identity. “America On The Brink” is the creation of published author, William ... several great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the ... today its plans to open a flagship location in Covington, LA at 401 N. ... To Go store next to Office Depot in the Holiday Square shopping center. Its ...
(Date:10/12/2017)... ... 2017 , ... The American College of Medical Informatics (ACMI) will present the ... Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium ... a pioneer in the field of medical informatics, this prestigious award is presented to ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. ... recently contributed a medical article to the newly revamped Cosmetic Town journal ... spotlights the hair transplant procedure known as Follicular Unit Extraction (FUE). ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... Md. , Sept. 22, 2017  As the ... Republican Senators Bill Cassidy (R-LA) and ... Information notes that the medical device industry is in ... medical device tax, the 2.3% excise tax on medical ... But they also want covered patients, increased visits and ...
(Date:9/19/2017)...   ZirMed Inc ., a recognized leader in cloud-based ... has been ranked #1 by its users for the seventh ... User Survey. ZirMed was recognized as the top-ranked end-to-end revenue ... centers over 200 beds and holds one of the longest ... history. ...
(Date:9/13/2017)...   OrthoAtlanta has been named the official orthopedic ... (AFHC) for the 2018 College Football Playoff (CFP) National Championship ... Stadium in Atlanta, Georgia . OrthoAtlanta is ... campaign, participating in many activities leading up to, and including ... ...
Breaking Medicine Technology:
Cached News: