Traffic fumes damage DNA

Traffic fumes damage DNA, finds a small study in Occupational and Environmental Medicine.

To gauge the levels of exposure to traffic fumes, the research team assessed the amount of a chemical called 1-OHPG in the urine of 47 female motorway toll-booth operators and 27 female office workers.

The 20 toll booths were located on a motorway 10 km south of Taipei, Taiwan, and have the highest traffic density of any toll station in the country.

To test the effects of exposure, they measured 8-OHdG in the urine. This is an indicator of DNA damage caused by oxygen free radical activity in the body.

Blood samples were also taken to measure the levels of circulating nitric oxide, which indicates harmful oxidation associated with traffic fumes.

The operators worked in eight hour shifts, for four consecutive days, before taking a day off. During their shift, they took breaks of between 30 and 45 minutes every couple of hours. They regularly changed lane booth, working a rotation system.

Smoking also increases the amount of urinary 8-OHdG, and there were more smokers among the office workers.

But levels of urinary 8-OHdG were an average of 90% higher among the non-smoking toll booth operators than they were among the office workers. Levels of nitric oxide were an average of 30% higher.

The levels of 1-OHPG were strongly linked to the levels of 8-OHdG. The higher the 1-OHPG, the higher was the 8-OHdG. And this held true even after adjusting for smoking or mode of transport to work.

The authors conclude that traffic fumes boost oxygen free radical activity and therefore DNA damage, and that environmental levels should be curbed to protect people's health.


Contact: Emma Dickinson
BMJ Specialty Journals

Page: 1

Related medicine news :

1. Hopkins begins human trials with donor adult stem cells to repair muscle damaged from heart attack
2. Research offers hope of new treatments for liver damage
3. Does the college experience damage your brain?
4. Mothers exposure to air pollutants linked to chromosome damage in babies
5. Cooling lessens brain damage in sick newborn babies
6. Antibody treatment partially reverses nerve damage in Alzheimer disease
7. New system may help babies avoid brain damage
8. Research offers hope of new treatments for liver damage plague
9. Study shows long-term use of NSAIDs causes severe intestinal damage
10. Nerve damage from alcoholism reversed after liver transplantation
11. An apple a day could protect against brain-cell damage

Post Your Comments:

(Date:9/1/2020)... (PRWEB) , ... September 01, 2020 , ... ... Surgeon with specialty fellowship training in aesthetic surgery of the face, breast, and ... – the only female-owned premier boutique plastic surgery and aesthetic practice in Southwest ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... Just found out your dear friend has ... heartbreaking when your friend or family member shares their diagnosis. Once the shock wears off, ... say the wrong thing? What are the best ways to help? Words are failing me. ...
(Date:8/31/2020)... MARLBORO, N.J. (PRWEB) , ... August 31, 2020 ... ... the leading cloud-based business management solution for chiropractors, announced today the launch of ... telehealth, healthcare professionals can start running their virtual practice in under 90 seconds. ...
(Date:8/31/2020)... ... ... economic outlook continues to put financial strain on many of us, so it just makes ... monthly expenses and put more into savings, if possible. , “That’s a great way to ... in place in case something were to happen to you,” says Lee Duncan, CMO & ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... both directly with persons with autism and other developmental disabilities, as well as ... intervention, parent education, adolescents with autism, school consultation, and staff development. She joined ...
Breaking Medicine News(10 mins):
(Date:8/28/2020)... ... , ... Dr. Mark Surrey has been in practice for over 25 ... professor in the Department of OBGYN at UCLA’s David Geffen School of Medicine. ... Society and is a Clinical Director of Fellowship Training for UCLA & Cedars Sinai ...
(Date:8/27/2020)... ... 2020 , ... The flu season is right round the corner and the risk of getting ... necessary measures before it begins to harbor its effects on us. Already with the sudden ... huge impact on our lives. Hence it has become even more relevant to keep oneself ...
(Date:8/27/2020)... ... 27, 2020 , ... The GHT Companies , a leading developer and ... Feeding San Diego with a press conference at its manufacturing facility in Vista. ... of $5,000.00+ representing an overall donation result exceeding $30,000 to Feeding San Diego, Who: ...
Breaking Medicine Technology:
Cached News: