Treatment for brain tumor does not always follow recommendations

nt) and antiepileptic medications (n = 497; 88 percent), but few received antidepressants (n = 38; 8 percent) or prophylactic heparin (n=42; 7 percent). Most received radiation therapy (n = 479; 87 percent) in addition to other therapy, but fewer received chemotherapy (n = 300; 54 percent). Practice patterns varied significantly between academic and community settings.

"We present patterns of care for a large group of patients with newly diagnosed malignant glioma treated in the modern era. Some common practice patterns are in keeping with published literature (e.g., use of radiation therapy), some contradict published guidelines (e.g., frequent prophylactic antiepileptic drug administration) or may conflict with published literature (e.g., relatively infrequent use of chemotherapy), and still others point out areas for further investigation in this population, including heparin prophylaxis for venous thromboembolism, antidepressant medication, corticosteroid dosing, and use of surgical adjuncts. Variations in patterns of care were associated with differences in survival; establishing further practice guidelines may help reduce this variability. One of the major benefits of the GO Project is that it provides a broad historical cohort that can be used as a comparison for future prospective studies," the authors conclude.

(JAMA. 2005;293:557-564. Available post-embargo at JAMA.com)

Editor's Note: For funding and financial disclosure information, please see the JAMA article.

Editorial: Malignant Gliomas in 2005 - Where to GO From Here?

In an accompanying editorial, Paul Graham Fisher, M.D., of Stanford University, Stanford, Calif., and Patricia A. Buffler, Ph.D., of the University of California, Berkeley discuss the findings by Chang et al.

"Where should treatment of gliomas go from here? Neuro-oncology requires a major paradigm shift and substantial changes in treatment and rese

Contact: Carol Hyman
JAMA and Archives Journals

Page: 1 2 3

Related medicine news :

1. Treatment of cardiac lesions without anaesthesic
2. Treatment guidelines for kids with bipolar disorder published
3. University of Washington joins new Autism Treatment Network to provide better medical services
4. Advances in Skeletal Anabolic Agents for the Treatment of Osteoporosis: A scientific meeting
5. Treatment of ductal carcinoma in situ varies widely in United States
6. Treatment options expand for patients with neuropathic pain
7. Treatment interruption shows no benefit in drug-resistant HIV infection
8. Peanut Allergy: Major Advances in Treatment and Education
9. Release of results of Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial
10. Treatment helped reduce dose of inhaled corticosteroids while maintaining asthma control
11. Treatment for behavioral disorders in children with autism

Post Your Comments:

(Date:12/8/2019)... ... December 08, 2019 , ... Intelligent.com, ... the Top 26 Logistics Degree Programs for 2020. The comprehensive research guide is ... Each program is evaluated based on curriculum quality, graduation rate, reputation, and post-graduate ...
(Date:12/6/2019)... ... December 06, 2019 , ... Connecticut is ... and excellence in patient care. On December 12th, Hartford Business Journal will recognize ... Health Care Heroes Awards at the Hartford Marriott. , “We are fortunate to ...
(Date:12/6/2019)... , ... December 06, 2019 , ... ... preferred HIPAA compliance solution for the Wyoming Medical Society. Compliancy Group is dedicated ... Healthcare entities have an obligation to adhere to the standards set forth by ...
(Date:12/5/2019)... (PRWEB) , ... December 05, 2019 , ... ... offering new, high resolution ultrasound (HRUS) technology to help their patients more easily ... Chesterfield, MO, is participating in this study and reporting on his experience. While ...
(Date:12/5/2019)... ... December 05, 2019 , ... It’s been an impactful year ... help people embrace, achieve, and maintain a healthy lifestyle to giving generously to ... our mission of impacting world health, so it’s gratifying to look back on ...
Breaking Medicine News(10 mins):
(Date:12/6/2019)... (PRWEB) , ... December 06, 2019 , ... ... on development of treatments for psychiatric and neurodegenerative disorders, announced today that the ... application for NBTX-001 Inhaler, allowing the Company to initiate its Phase 2b trial ...
(Date:12/6/2019)... , ... December 06, 2019 , ... ... of global MSA research, recently unveiled its bold new initiative to kickstart MSA ... in the middle-years of life. , Infused by $3 million in new bequests ...
(Date:12/5/2019)... ... December 05, 2019 , ... Intelligent.com, a trusted resource for ... Therapy Degree Programs for 2020. The comprehensive research guide is based on an ... evaluated based on curriculum quality, graduation rate, reputation, and post-graduate employment. , ...
Breaking Medicine Technology:
Cached News: