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Treatment helped reduce dose of inhaled corticosteroids while maintaining asthma control

of lung function) of 80-81 percent predicted and mean daily albuterol use (a measure of asthma control) of 0.82 puffs per day. All patients participated in the study for at least 12 weeks; and all patients (n=308) from a subset of study sites were randomized to treatment that continued for 24 weeks.

Overall, both of the treatments (Advair Diskus 100/50 BID and FP 250 mcg BID) were well tolerated. The incidence of common and pharmacologically predictable adverse events over the study period were similar for both treatments.

Advair Diskus is indicated for the long-term, twice-daily, maintenance treatment of asthma in patients 12 years of age and older. Advair is not indicated for the relief of acute bronchospasm, and does not replace fast-acting inhalers for the treatment of sudden symptoms. People switching from an oral steroid like prednisone to Advair, which contains an inhaled steroid, need to be especially careful. While adjusting to the switch, a person may not be as able to heal after surgery, infection or serious injury. Advair should be used with caution in patients with cardiovascular disorders. Some patients may experience increased blood pressure, heart rate or changes in heart rhythm. Patients should see their doctor if their asthma does not improve.


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6-Nov-2002


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