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Treatment interruption shows no benefit in drug-resistant HIV infection

icipated in the study, the length of follow-up and the fact that there was a randomized comparison with a control group. These features allowed the researchers to study the overall impact of structured treatment interruption, including the effects on AIDS-related illnesses, HIV viral load, CD4+ T-cell count and quality of life."

"It is important to remember," adds Dr. Fauci, "that the failure of treatment interruption seen in this study pertains only to individuals who had drug-resistant HIV and detectable virus in their blood when they entered the study. For individuals who are being successfully treated with anti-HIV medications, other studies have shown that cycles of treatment interruptions for shorter periods may be of potential benefit to conserve medications and reduce drug-related toxicities."

The CPCRA is a national community-based clinical trials network whose main goal is to inform healthcare providers and diverse populations of people living with HIV about the most appropriate use of HIV therapies.


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Contact: John Bowersox
jbowersox@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
27-Aug-2003


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