HOME >> MEDICINE >> NEWS
Tuberculosis strains stay close to home, say Stanford researchers

STANFORD, Calif. - Taking advantage of the open-air laboratory that is San Francisco, Peter Small, MD, has collected samples of virtually every case of tuberculosis that has occurred in the city for the last 13 years - almost 3,000 total. In this week's advance online edition of The Proceedings of the National Academy of Sciences, the associate professor of infectious diseases and geographic medicine at the Stanford University School of Medicine and his colleagues present a genetic analysis of 100 of these samples. The findings suggest ways the bacteria can escape a host's immune system or develop antibiotic resistance.

The team took its analysis a step further in a second paper, which appears in the same edition of the journal. They found that people from different regions of the world carry different strains of the tuberculosis bacteria, pointing out the importance of sociological interactions in infectious disease transmission. This also raises the possibility that the pathogen evolves within a geographic population group and doesn't spread to other groups.

"It was remarkable how well the genetics mapped to global geography," said Small. "Co-evolution is highly speculative, but it's an intriguing possibility. Most importantly, it's a hypotheses we now have the technology to address."

Tuberculosis causes more adult deaths than any other infectious disease. Worldwide, one person in three is infected, but it remains a problem primarily in the developing world. However, the emergence of tuberculosis strains resistant to multiple drugs in industrialized countries is prompting renewed interest in vaccination.

There has long been anecdotal evidence that tuberculosis bacteria differ throughout the world, said Small, who is currently on leave from Stanford serving as a senior program officer in the Global Health Program of the Bill and Melinda Gates Foundation. Additionally, he said, studies testing tuberculosis vaccines have varied widely
'"/>

Contact: Mitzi Baker
650-725-2106
Stanford University Medical Center
15-Mar-2004


Page: 1 2 3

Related medicine news :

1. Tuberculosis drug combined with virtual reality therapy is effective in treating fear of heights
2. UCSD Medical Center receives NIH contract to set up National Tuberculosis Educational Curriculum
3. Tuberculosis Foundation selects Core Research Scientists
4. New quick test for drug-resistant strains of gonorrhea
5. Nabi StaphVAX elicits antibodies with in vitro activity against antibiotic-resistant Staphylococcus aureus strains
6. War on bacteria could leave drug-resistant strains unchecked
7. New data provide further evidence of effectiveness of targeted delivery of Relenza and efficacy in both A&B strains
8. Indiana University researchers closer to helping hearing-impaired using stem cells
9. Chemicals in tattoo inks need closer scrutiny
10. Researchers close in on breast cancer vaccine
11. Drug companies should disclose adverse events before licensing

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/8/2016)... ... 2016 , ... After enjoying record-breaking attendance at its last ... 33rd Annual Issues & Research Conference, March 2-3, 2017, at the Westin ... is “Persistent Challenges and New Opportunities: Using Research to Accelerate the Dialogue." 2016 ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... announce that “Natural Language Processing–Enabled and Conventional Data Capture Methods for Input to ... Medical Informatics . , Results of the comparative usability study demonstrate that a ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... Medication Therapy Management (MTM), adherence, and other pharmacist-delivered patient care services, has announced ... counsel and Eric Hoessel to vice president of sales. , Litsinger joined ...
(Date:12/8/2016)... ... ... With the increasing demand for dental implants, the National Association of Dental ... dentists and patients about the safety issues related to dental restorations. According to the ... is projected to reach $6.4 billion in 2018 with more than 30 million Americans ...
(Date:12/8/2016)... ... December 08, 2016 , ... Premier Fitness Camp (PFC) and The Chopra ... weight loss and wellness program, at their world headquarters of Omni La Costa Resort ... long-term results to anyone seeking weight loss, personal development, a healthy lifestyle, or mental ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... Allergy Diagnostics Market: Scope and Methodology ... are used to determine the presence of allergens ... etc. in the samples by determining the presence ... report on global allergy diagnostics market, analyzes the ... report consists of an executive summary that provides ...
(Date:12/8/2016)... DUBLIN , Dec 8, 2016 Research and Markets ... Report" report to their offering. ... This report analyzes the worldwide markets for ... US, Canada , Japan , ... , and Rest of World. Annual estimates and forecasts are provided ...
(Date:12/8/2016)... Mederi Therapeutics Inc . anunciou aprovação regulatória, pela CFDA, e lançamento de ... refluxo gastroesofágico (DRGE). Foto -  http://photos.prnewswire.com/prnh/20161207/446903 ... ... procedure performed and broadcast during the Chinese Congress of Digestive Endoscopy, by Professor ... , , ...
Breaking Medicine Technology:
Cached News: