Type 1 diabetes safely arrested with short-term use o...( by fusing certain parts of a mouse ant...)

Type 1 diabetes safely arrested with short-term use of new drug

by fusing certain parts of a mouse antibody with that of a human antibody to retain the desired binding specificity without provoking an immune response as a mouse antibody would.

It is less toxic than cyclosporine and other earlier immunosuppressive drugs because it is administered for only two weeks. Briefer immunosuppression prevents the side effects which were severe in some cases with the earlier drugs including infections and cancer. Moreover, the drug is more specific and does not cause other organ toxicity such as kidney disease.

It is less toxic than other OKT3 monoclonal antibody drugs because it doesnt activate aggressive inflammatory cytokines of the immune system, which have led to fever, nausea, headache, hypertension and even cardiac problems. This drug was developed by mutating a portion of the antibody so that it does not activate T cells thus avoiding the release of the cytokines.

'"/>

Contact: Annie Bayne
as862@columbia.edu
212-305-3900
Columbia University Medical Center
29-May-2002

Page: 1 2 3 4 5
Related medicine news :

1. Waist size linked to diabetes risk in adult men
2. Employees with diabetes are not more tired
3. Compound may help prevent diabetes in fast-food fans
4. Drugs aid weight loss among type 2 diabetes patients
5. Single-donor islet transplantation procedure shows promise for patients with type 1 diabetes
6. Herb used to treat diabetes works like modern-day prescription drugs, study suggests
7. Study shows that diabetes increases risk of blood poisoning
8. Lifestyle changes especially effective at preventing type 2 diabetes in adults aged 60 and older
9. Elevated glucose levels and diabetes are associated with increased risk for cancer
10. Weight loss strategies work in people with pre-diabetes
11. Anti-psychotic drugs may be associated with increased risk of diabetes in schizophrenia patients

Post Your Comments:

(Date:11/7/2009)...ire-USNewswire/ -- The U.S. bishops November 7 urg... for the Stupak-Ellsworth Amendment to the health ...tur-Dahlkemper-Lipinski-Smith Amendment will keep ...nd conscience protections in the Affordable Health..., The letter was signed by Cardinal Justin Rigali...

(Date:11/7/2009)...youth will rebel, expert says , , SATURDAY... to behave badly if their parents expect them to, ... they are simply being realistic might actually co...uchanan, a psychology professor at Wake Forest Uni...ersity news release. "Negative expectations on the...

(Date:11/7/2009)...lsquo;sweatox’ or ‘Boytox’, the ...nti-ageing jab ‘Breastox’ – or b...e;colletage, can reduce the appearance of wrinkles...easts, leaving smoother, younger-looking skin. , ...- Transform, the UK’s largest group of cosm...

(Date:11/6/2009)...US, Ohio, Nov. 6 Authentidate Holding Corp. (Nasd... Information Exchange and workflow management serv...rybe® Healthcare to be easily integrated with...n systems, Definitive Homecare Solutions, CPR+(TM)...+ Integrated Solutions Provider program, a program...

(Date:11/6/2009)...care Trust of America, Inc. (the "REIT"), a self-m...announced the execution of a Purchase and Sale Agr...ce building located in Englewood, Colorado for app...cal Center is located within the Englewood City Ce...district. Hampden Place is located near the Swedis...

Breaking Medicine News(10 mins):Health News:Bishops Urge Passage of Stupak-Ellsworth Anti-Abortion Amendment for Health Reform Bill 2 Health News:Bad-Behaving Teens May Be Living Up to Expectations 2 Health News:UK Boobs Get a Boost with 'Breastox' 2 Health News:Authentidate Introduces New Interface for Inscrybe Healthcare with Definitive Homecare Solutions' CPR+ 2 Health News:Authentidate Introduces New Interface for Inscrybe Healthcare with Definitive Homecare Solutions' CPR+ 3 Health News:Authentidate Introduces New Interface for Inscrybe Healthcare with Definitive Homecare Solutions' CPR+ 4 Health News:Healthcare Trust of America, Inc. Executes Agreement to Acquire a 66,339 SF Medical Office Building Located in Englewood, Colorado 2 Health News:Healthcare Trust of America, Inc. Executes Agreement to Acquire a 66,339 SF Medical Office Building Located in Englewood, Colorado 3

[0] Bishops Urge Passage of Stupak-Ellsworth Anti-Abortion Amendment for Health Reform Bill [0] Bad-Behaving Teens May Be Living Up to Expectations [0] UK Boobs Get a Boost with 'Breastox'[0] Authentidate Introduces New Interface for Inscrybe Healthcare with Definitive Homecare Solutions' CPR+[0] Healthcare Trust of America, Inc. Executes Agreement to Acquire a 66,339 SF Medical Office Building Located in Englewood, Colorado

(Date:11/6/2009)...EG, Manitoba, Nov. 6 With his prop...ma has set his sights on cutting name-brand prescr...nts who fall into the "Part D" coverage gap, unive...ave about the potential cost-cutting and feel it,s... of the most powerful lobbyists want a revised pro...

(Date:11/6/2009)...N, Nov. 6 Cyberonics, In...ny will report financial results for the second qu...ding April 30, 2010 on Wednesday, November 18, 200...erence call to discuss those results on Thursday, ...ear 2010 Second Quarter Results Conference Call In...

(Date:11/6/2009)...EGO, Nov. 6 California American Wa... "No Drugs Down the Drain" week for its San Diego ... sponsored by public and private agencies alike to... pollution in our source water supplies. ,, Cal...s are encouraged to drop off expired or unwanted p...

Breaking Medicine Technology:Obama Healthcare Reforms Fall Short, but Betterthanmedicare.com Closes the 'Donut Hole' 2 Obama Healthcare Reforms Fall Short, but Betterthanmedicare.com Closes the 'Donut Hole' 3 Cyberonics Announces Conference Call to Discuss Fiscal Year 2010 Second Quarter Financial Results 2 California American Water Celebrates 'No Drugs Down the Drain' Week in San Diego 2 Health Canada Approves Abbotts XIENCE V 28R 29 Drug Eluting Stent 55128 1 Health Canada Approves Abbotts XIENCE V 28R 29 Drug Eluting Stent 55128 2 Health Canada Approves Abbotts XIENCE V 28R 29 Drug Eluting Stent 55128 3 Health Canada Approves Abbotts XIENCE V 28R 29 Drug Eluting Stent 55128 4 Health Canada Approves Abbotts XIENCE V 28R 29 Drug Eluting Stent 55128 5 Research Consortium Advances Understanding of Cervical Spine Injuries in Children Involved in Motor Vehicle Crashes 4885 1 Research Consortium Advances Understanding of Cervical Spine Injuries in Children Involved in Motor Vehicle Crashes 4885 2 Research Consortium Advances Understanding of Cervical Spine Injuries in Children Involved in Motor Vehicle Crashes 4885 3 Glow in the dark red blood cells made from human stem cells 9680 1

[0] Obama Healthcare Reforms Fall Short, but Betterthanmedicare.com Closes the 'Donut Hole'[0] Cyberonics Announces Conference Call to Discuss Fiscal Year 2010 Second Quarter Financial Results [1] California American Water Celebrates 'No Drugs Down the Drain' Week in San Diego

Other News:

...ved the health prospects of individuals with sever...rted today at the American Heart Associations Scie...e practice of piercing the skin with needles at sp...amatically reduced sympathetic nerve activity amon...

... Eyes is more than a Broadway show-stopping song; ...tion is the leading cause of U.S. fire deaths. Eve...n be harmful to fire fighters and occupants of bui... someone to choose a dangerous escape route, reduc...

...rs, mounting scientific evidence has suggested tha...disease, but doctors and dentists cant say whether........Now a unique new study is starting at five ma...tion.......Faculty members at the University of No...

ST. PAUL, MN Electrical brain stimulation can reduce the problems Parkinson's patients develop after long-term use of the drug levodopa, the main treatment for Parkinson's, according to a study publi

health news:Acupuncture calms nerves, improves heart function 2 health news:Acupuncture calms nerves, improves heart function 3 health news:First report on sublethal effects of smoke available from NIST 2 health news:Unique study to begin examination of whether treating periodontal disease cuts heart disease 2 health news:Electrical brain stimulation reduces Parkinsons symptoms 2

Acupuncture calms nerves, improves heart function First report on sublethal effects of smoke available from NIST Unique study to begin examination of whether treating periodontal disease cuts heart disease Electrical brain stimulation reduces Parkinsons symptoms

...re more likely to underestimate how long it has be...ease -- such as a mammogram, Pap smear, or cholest...study that matched patient recollections with Medi... might be harming the health of minorities in the ...

...sex already have a partner, reveals a small survey...ctions.... The authors used survey data from a sta...more than 2500 men at one sexual health clinic bet...of the men said that they had paid for sex. Their ...

Transplant surgeons at Children's Hospital of Pittsburgh and UPMC have saved two patients with life-threatening liver conditions utilizing a technique known as a domino transplant. It is only the nati

...rug used to strengthen bones when cancer has sprea...es deterioration of the jaw bone, according to two...called osteonecrosis of the jaw, is marked by expo...lammation and pain....While researchers do not ful...

health news:Rochester study shows ethnic disparities in medicare claims 2 health news:Children's Hospital of Pittsburgh and UPMC surgeons save two lives with domino transplant 2 health news:Drug used for advanced cancer could cause exposed bone in jaw 2

Rochester study shows ethnic disparities in medicare claims Almost half of men who pay for sex already have a partner Children's Hospital of Pittsburgh and UPMC surgeons save two lives with domino transplant Drug used for advanced cancer could cause exposed bone in jaw

Type 1 diabetes safely arrested with short-term use o...( by fusing certain parts of a mouse ant...),Health