HOME >> MEDICINE >> NEWS
UB begins groundbreaking study on 'net effect' on patients of HIV treatments, other drugs

BUFFALO, N.Y. -- An antiretroviral drug for HIV, methadone for heroin addiction, a birth control pill and an antidepressant. For some AIDS patients, this is a daily medication regimen. Others take drugs to treat diabetes, opportunistic infections and side effects of antiretrovirals, while still others abuse alcohol, cocaine or heroin.

How do all of these substances affect how HIV drugs work and how do HIV drugs, in turn, affect the other drugs a patient takes?

That question is at the heart of research being conducted by the University at Buffalo's Laboratory for Antiviral Research, where researchers are developing innovative new methods of testing the blood and cells of HIV patients for these interactions.

The work is supported by a new, $2.3 million National Institutes of Health/National Institute for Drug Abuse grant to complete the first major study of complex drug interactions in AIDS patients.

"Fifteen years ago, we were treating people with one basic goal in mind: to prolong their lives," said Gene Morse, Pharm.D., principal investigator, professor and chair of the UB Department of Pharmacy Practice and associate dean of the School of Pharmacy and Pharmaceutical Sciences. "Now we have the drugs to suppress viral replication, but with them come another set of complications. Many of these drugs are interacting and it has been difficult to study all possible interactions during the FDA development process. We want to find out their net effect." The decision to propose a comprehensive study on how antiretroviral drugs interact with other drugs HIV patients take grew out of a recent, multi-year clinical pharmacology study of interactions with methadone by Morse and psychiatrists at New York City's Montefiore Hospital. "A big factor in treating HIV infection are those patients with concurrent substance addiction," explained Morse. "For example, some of the drugs patients take to treat HIV could actually put them into withdrawal from m
'"/>

Contact: Ellen Goldbaum
goldbaum@buffalo.edu
716-645-5000 x1415
University at Buffalo
3-Sep-2003


Page: 1 2 3

Related medicine news :

1. Hopkins begins human trials with donor adult stem cells to repair muscle damaged from heart attack
2. EuroVacc 02 HIV vaccine trial begins in February 2005
3. PENN begins clinical trial of newest technology to treat thoracic aortic aneurysms
4. International trial of two microbicides begins
5. NIAID begins enrolling volunteers for novel HIV vaccine study
6. National Center for Children Exposed to Violence begins annual conference today
7. Enrollment begins for osteoarthritis initiative
8. Patients should be consulted before dialysis treatment begins
9. Clinical trial of new TB vaccine begins
10. First US tuberculosis vaccine trial in 60 years begins
11. UCSF begins study testing antiviral drug tenofovir to prevent HIV infection

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/13/2019)... MIAMI (PRWEB) , ... February 14, 2019 , ... At ... 20,000 global entrepreneurs leapt to their feet and cheered as it was announced that ... Over the course of the last few years, the company has optimized its revolutionary ...
(Date:2/13/2019)... ... February 13, 2019 , ... ... announced ‘ Energizing Health @ SXSW ,’ four days of programming occurring ... for community advocates, entrepreneurs, health organizations, industry and philanthropy to innovate, collaborate ...
(Date:2/13/2019)... ... February 13, 2019 , ... That wintry landscape outside the window ... from walkways and driveways. Then, the snow can quickly become a pain in the ... use to remove it,” says noted orthopaedic surgeon Kevin D. Plancher, MD, MPH ...
(Date:2/13/2019)... ... February 13, 2019 , ... Dr. Jig Patel and the dental ... an exceptionally talented and knowledgeable dentist from St. Louis, MO, to the ... such as CEREC same-day dentistry, root canals and emergency treatment. Dr. Patel, Dr. Merchant ...
(Date:2/13/2019)... MESA, Calif. (PRWEB) , ... February 13, 2019 , ... ... healthcare scholarship. Open to students who choose to pursue a medical-related course of study ... describe their passion for substance abuse disorder and mental health treatment, and how it ...
Breaking Medicine News(10 mins):
(Date:2/14/2019)... (PRWEB) , ... February 14, 2019 , ... ... physicians of Asheville Radiology Associates (ARA), in Asheville, North Carolina. , “We ... the many collaborative opportunities available through Strategic Radiology,” said Arl Van Moore Jr, ...
(Date:2/13/2019)... ... February 13, 2019 , ... NCPDP announced ... the keynote speech on Wednesday, May 8, at its 2019 Annual Technology & ... Westin Kierland Resort & Spa in Scottsdale, Arizona, and is expected to draw ...
(Date:2/13/2019)... ... February 13, 2019 , ... Wound Care centers across the country ... software as an app inside their hospital’s EHR, substantially improving continuity of care ... (electronic health record) pioneer, will soon launch its award-winning software as an “app” capable ...
Breaking Medicine Technology:
Cached News: