UCI biomedical engineer receives $1.8 million grant

Irvine, Calif., Aug. 13, 2003 -- UC Irvine biomedical engineer Steven C. George, who is one of the first U.S. scientists to create three-dimensional living lung tissue, has received a $1.8 million grant from the National Institutes of Health to examine how asthma attacks the walls of the bronchial tubes.

"People with asthma develop a fibrosis on the walls of their airways that becomes increasingly worse as the disease progresses," said George, the William J. Link Professor and chair of the Department of Biomedical Engineering, who also holds an appointment in the Department of Chemical Engineering and Materials Science.

"Scientists aren't sure if the disease causes the fibrosis or if the reverse is true, but understanding the process will help us develop more effective asthma treatments."

George will create viable lung tissue similar to that found in bronchial tubes, then injure the tissue by compressing and scraping it, simulating the injuries that occur with asthma. His research team will analyze the damaged tissue with a laser-scanning microscope to better understand what causes scarring in the lungs of people with asthma.

To create the tissue for this project, George will use collagen fibers harvested from connective tissue in the tails of rats and human lung cells. Once created, the viable lung tissue will be approximately the size and thickness of a penny, and live on a specialized solution of salts, sugars and antibiotics.

George's research team includes doctoral graduate students Justin Mih and Jinping Wan and staff research associate Julie Papp. Postdoctoral scholar Roel Bruels will join the team next month. The five-year grant comes from the National Heart, Lung and Blood Institute, part of the National Institutes of Health. Asthma is one of the nation's leading heath issues, especially among children and the elderly. Some 17 million Americans suffer from the chronic lung disease. Nearly 500,000 Americans are ho

Contact: Nicole Knight
University of California - Irvine

Page: 1 2

Related medicine news :

1. Privacy rule builds biomedical research bottleneck
2. OHSU receives grant to study evolutionary computing for biomedical image analysis
3. NIH grants support health disparities biomedical research
4. Molecular self-assembly techniques used to coat biomedical substrates
5. Clay reduces permeability of biomedical polymer
6. Rice scientist recognized as pioneer in tissue engineering
7. Rice cartilage experts win $1.5M NIH grant to bioengineer TMJ discs
8. Lab study: Protein delivered via genetically engineered virus slowed glioblasoma multiforme growth
9. New Jersey Institute of Technology pioneers new way to teach engineers
10. Rice engineers demo first T-ray endoscope
11. U-M team treating mouth wounds by engineering tissue grafts

Post Your Comments:

(Date:9/15/2018)... ... September 14, 2018 , ... Today, Mediaplanet announces the launch ... work being done within rare diseases research, diagnostics, and will highlight what industry ... diseases. , Clay Matthews, Super Bowl-winning linebacker for the Green ...
(Date:9/13/2018)... ... September 13, 2018 , ... Pulsara is honored to ... + Revenue Cycle Conference on September 19-22 in Chicago. Dr. Woodson, ER Physician ... well as a talk titled, “Your Clinical Communication & Collaboration (CC&C) is Not Enough: ...
(Date:9/12/2018)... ... , ... Donaldson Plastic Surgery has been included on the Inc. 5000 list ... list of central Ohio's fastest growing businesses. The plastic surgery practice was ranked number ... is the only medical practice and plastic surgery office to make the regional Fast ...
(Date:9/7/2018)... ... September 07, 2018 , ... ... District , the only OSHA authorized OTI Education Center headquartered in Northern California, ... employees who feel they have experienced retaliation in response to engaging in activity ...
(Date:9/2/2018)... ... 2018 , ... Eaton Hotel in Washington, DC is a ... opened this week, inspires creativity and innovation among its guests, whether they are ... currently features 209 hotel rooms, a wellness center, a radio station, a meeting ...
Breaking Medicine News(10 mins):
(Date:9/13/2018)... ... , ... Dr. Rod J. Rohrich is pleased to announce that registration is ... experts from around the world, will take place from March 22nd and 23rd, 2019. ... anatomy to complex surgical procedures and detailed analysis of revision rhinoplasty . Formats ...
(Date:9/13/2018)... , ... September 13, 2018 , ... ... to know | 2018" list. , Hospitals and health systems rely on CIOs ... as well as support telehealth, data-gathering and cybersecurity initiatives. Those who lead community ...
(Date:9/12/2018)... ... September 13, 2018 , ... Safety ... Sept. 27, 2018 — 1:30 p.m. – 3:00 p.m. ET, http://info.fdanews.com/safety-reporting-in-global-clinical-trials ... by as much as fifty percent. , This can be due to ...
Breaking Medicine Technology:
Cached News: