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UCI study uncovers how plaque in neck artery leads to stroke-inducing blood clots

form into clots. This suggests that early detection and treatment of carotid-artery plaques before these ulcerations grow can benefit people who exhibit stroke risk factors such as hypertension, elevated cholesterol, diabetes or a previous stroke.

"As carotid-imaging technologies improve, identification of both ulceration and blood-clot development will assist in the decision for removal of carotid-artery plaques," said Fisher, professor and chair of neurology in the UCI School of Medicine.

Dr. Annlia Paganini-Hill, Aldana Martin and Dr. Michele Cosgrove of the University of Southern California in Los Angeles; Dr. James F. Toole of the Wake Forest School of Medicine in Winston-Salem, N.C.; Dr. Henry J.M. Barnett of the John P. Robarts Research Institute in London, Ont., and Dr. John Norris of the St. George Hospital Medical School in London, England, assisted with the study. The National Institutes of Health provided funding support.

The UCI Stroke Center's clinical activities are located in the UCI Medical Center, which is the first academic medical center in the nation to be certified by the Joint Commission on Accreditation of Healthcare Organizations for stroke care.


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Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine
7-Feb-2005


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