HOME >> MEDICINE >> NEWS
UCL study questions basis for treatment of diseases including cancer and arthritis

One of the methods for treating diseases that include cancer, arthritis and radiation sickness is challenged by new research by a team of scientists at University College London (UCL). The current orthodoxy on the role played by oxygen free radicals in the development of a number of diseases is called into question by the UCL team in a paper to be published in the 26th February edition of Nature, in research that may hold profound implications for the standard approach of the medical profession and pharmaceutical industry in treating these conditions.

It is currently held that oxygen free radicals, atoms or groups of atoms produced by white blood cells, are responsible, if produced in excess, for the production of conditions such as arthritis, arteriosclerosis and many others, including cancer. That is why, since the 1970s, medical practice and the pharmaceutical industry have sought to develop drugs to stop the production of free radicals and mop them up with antioxidants (substances capable of preventing the oxidation of organic molecules) as part of the process of treating such diseases.

Following extensive study, the paper categorically discounts the primary evidence upon which this theory is based, and suggests that instead we need to look at other potential treatments, and that specifically treatments should move towards the regulation of enzymes released from neutrophil leukocytes, the most numerous of the white blood cells.

"White blood cells produce oxygen free radicals, and the process by which they do so is essential for the efficient killing of microbes," says Professor Tony Segal of the Centre for Molecular Medicine within UCL's Department of Medicine, one of the authors of the research. "However, people in whom this process is defective are prone to severe, chronic and often fatal infections. This fact has led to the presumption that the oxygen free radicals themselves are highly toxic, and that if they can kill org
'"/>

Contact: Dominique Fourniol
d.fourniol@ucl.ac.uk
44-207-679-9728
University College London
25-Feb-2004


Page: 1 2

Related medicine news :

1. First head-to-head study to compare lidoderm patch and Celebrex in treating pain
2. UMaine study looks at infants and chronic nighttime crying
3. Chronic pain treatments more effective when taken together, new study shows
4. UNC study: Most N.C. family practitioners engage in unrecognized community service
5. New study in Nature demonstrates protection against cell death during heart attack
6. UCSF study offers insight into human circadian rhythms
7. International breast cancer prevention study launches in the United States and Canada
8. UW study shows blacks and Latinos are more satisfied with physicians of the same race
9. Physicians may not be accurate in their confidence levels of their diagnoses, says Pitt study
10. Advertising by academic medical centers may risk eroding public trust, says study
11. Fat may promote inflammation, new study suggests

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... August 31, 2020 , ... Smile ... dental groups in the United States, today announced the grand opening of another ... , Patients will enjoy convenient hours, a comfortable office, and full-service care ...
(Date:8/31/2020)... , ... August 31, 2020 , ... A Cure for Covid-19 “PTS” with Mediation & ... the planet are in a state of panic, experiencing deep anxiety, immense stress, and right ... a solution is timely when most people on the planet are experiencing a great degree ...
(Date:8/31/2020)... ... August 31, 2020 , ... Dr. ... with persons with autism and other developmental disabilities, as well as supporting staff ... education, adolescents with autism, school consultation, and staff development. She joined the company ...
(Date:8/29/2020)... , ... August 29, 2020 , ... When professor and ... with greater ease than most people would. Rather than become melancholic, however, he put ... advice on achieving one’s dreams. Randy Pausch took a negative situation and turned it ...
(Date:8/28/2020)... ... 28, 2020 , ... WHAT , Hespiro™ is a new ... conditions, including COVID-19, while reducing the need for scarce mechanical ventilators. It not ... and scrubs it free of carbon dioxide in a completely closed “rebreather” system, ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... (PRWEB) , ... September 01, 2020 , ... ... laboratory technologies, will host the Agilent Science and Technology Virtual Symposium 2020 ... two-day symposium, Agilent will open a suite of Live webinars and Networking sessions, ...
(Date:9/1/2020)... ... September 01, 2020 , ... September is National Ovarian ... for more deaths than any other cancer of the female reproductive system. The ... ovarian cancer and about 14,000 women will die from this disease. Throughout the ...
(Date:8/28/2020)... ... August 28, 2020 , ... Cano Health, ... centers in Florida and San Antonio is happy to announce that it has ... , In this capacity he will serve as community advisor, advertising talent, and ...
Breaking Medicine Technology:
Cached News: