HOME >> MEDICINE >> NEWS
UCLA study examines origins of fatigue in breast cancer survivors

Persistent fatigue in breast cancer survivors might be associated with a chronic inflammatory process involving T cells, according to a new UCLA study published Aug. 6 in the Journal of the National Cancer Institute.

About 30 percent of women successfully treated for breast cancer suffer persistent fatigue of unknown origin. Earlier studies have found elevated levels of several inflammatory markers in circulating blood among breast cancer survivors experiencing fatigue.

To identify the immunologic basis for these elevations, Julienne E. Bower, a researcher at UCLA's Jonsson Cancer Center and an assistant professor at the UCLA Neuropsychiatric Institute's Cousins Center for Psychoneuroimmunology, and colleagues examined cellular immune system status in 20 fatigued breast cancer survivors and 19 matched non-fatigued breast cancer survivors.

Fatigued survivors, compared with non-fatigued survivors, had statistically significantly increased numbers of circulating T lymphocytes, with pronounced elevation in the numbers of CD4+ T lymphocytes and CD56+ effector T lymphocytes.

These changes were independent of patient demographic and treatment characteristics. The increased numbers of circulating T cells correlated with elevations in the level of serum interleukin 1 receptor antagonist (a marker of inflammation). The authors note that these results require confirmation in a larger study.


'"/>

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-206-2805
University of California - Los Angeles
7-Aug-2003


Page: 1

Related medicine news :

1. First head-to-head study to compare lidoderm patch and Celebrex in treating pain
2. UMaine study looks at infants and chronic nighttime crying
3. Chronic pain treatments more effective when taken together, new study shows
4. UNC study: Most N.C. family practitioners engage in unrecognized community service
5. New study in Nature demonstrates protection against cell death during heart attack
6. UCSF study offers insight into human circadian rhythms
7. International breast cancer prevention study launches in the United States and Canada
8. UW study shows blacks and Latinos are more satisfied with physicians of the same race
9. Physicians may not be accurate in their confidence levels of their diagnoses, says Pitt study
10. Advertising by academic medical centers may risk eroding public trust, says study
11. Fat may promote inflammation, new study suggests

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/19/2017)... ... 19, 2017 , ... "At your fingertips" electronic access to ... the Delaware Health Information Network (DHIN) have partnered to improve connectivity of this ... information exchange, DHIN stores and shares real-time health data for more than 2 ...
(Date:2/18/2017)... ... February 17, 2017 , ... CONTACT:, Glenn Vallecillos, MD, ... plastic surgeon Dr. Glenn Vallecillos experiments SculpSure, the hot, new, aesthetic, ... surgery has been centered around that idea that to achieve ones desired results ...
(Date:2/17/2017)... ... February 17, 2017 , ... While EHR data has ... introduced an innovative workstation designed to reduce nursing fatigue while enhancing productivity. Based ... Workstation offers a lightweight, highly mobile, multi-functional alternative to the limitations of handheld ...
(Date:2/17/2017)... ... February 17, 2017 , ... Empowering each person's mental functions, ... each and every seminar, session and class she offers. At the International ... which help energize creativity, focus mental functions, enhance athletic focus and skill sets, ...
(Date:2/17/2017)... ... February 17, 2017 , ... MAP Revenue Cycle Solutions ... Pilley has been promoted to Chief Executive Officer. , The need for ... a shift that demands the transition from pay-for-service to pay-for-performance models. By delivering ...
Breaking Medicine News(10 mins):
(Date:2/17/2017)... Conn. , Feb. 17, 2017 Arvinas ... of drugs based on protein degradation, today announced the ... receptor (AR) PROTAC during a poster session at the ... (ASCO GU) in Orlando, FL. ... to validate our platform and the potential of PROTACs ...
(Date:2/17/2017)... YORK , Feb. 17, 2017   Risperdal ... side effects allegedly associated with use of the atypical ... Philadelphia Court of Common Pleas, where ... mass tort program. According to a notice posted on ... to convene a meeting on March 9, 2017 at ...
(Date:2/17/2017)... 17, 2017 On Thursday, February ... edged lower at the closing bell, while the Dow ... 20,000 benchmark. Moreover, five out of nine sectors ended ... yesterday,s market sentiment, Stock-Callers.com assessed the following Medical Appliances ... (NYSE: SNN ), ABIOMED Inc. (NASDAQ: ...
Breaking Medicine Technology:
Cached News: