HOME >> MEDICINE >> NEWS
UCSD researchers determine fatty liver disease different in obese children than in adults

Potentially life-threatening non-alcoholic fatty liver disease (NAFLD) in obese children has distinct characteristics, often different from those found in adults, according to a University of California, San Diego (UCSD) School of Medicine study led by Jeffrey Schwimmer, M.D., assistant professor of pediatrics.

Presented May 18, 2004 at the annual Digestive Disease Week meeting in New Orleans, the largest international gathering of gastroenterology and hepatology physicians, surgeons and researchers, the findings describe a new paradigm for diagnosis of this common condition found in obese children and offer the potential for improved care.

Between 1997 and 2003, the investigators identified 100 children ages 2 to 18 with biopsy-proven NAFLD. They found clearly different patterns and locations of liver scarring and inflammation in children as compared to that typically seen in adults. Focusing on the most severe form of NAFLD, called nonalcoholic steatohepatitis, or NASH, the researchers divided it into two types which they named Type 1 (the classic adult pattern) and Type 2 (a proposed pediatric pattern).

Specifically, the researchers found that Type 2 NASH was more than three times as common as Type 1 NASH in children. Advanced liver scarring and cirrhosis were seen only in children with Type 2 NASH. In addition, they found that boys were more likely than girls to have Type 2 NASH and less likely to have Type 1. Type 2 NASH was also more common in children of non-white race or Hispanic ethnicity.

Schwimmer, director of the Fatty Liver Clinic at Children's Hospital in San Diego, noted that "many obese children will already have NAFLD without any symptoms. Our data suggest particular groups of children at risk for advanced disease. We believe that the different injury patterns in children suggests differences in causation and potentially treatment and outcome. Additionally, we speculate that Type 2 NASH may also occur in ad
'"/>

Contact: Sue Pondrom
spondrom@ucsd.edu
619-543-6163
University of California - San Diego
18-May-2004


Page: 1 2

Related medicine news :

1. Indiana University researchers closer to helping hearing-impaired using stem cells
2. Protein that helps skin cancer spread identified by Stanford researchers
3. US life expectancy about to decline, researchers say
4. Gene for age-related macular degeneration discovered by Yale researchers
5. Dartmouth researchers find where musical memories are stored in the brain
6. Columbia researchers receive $3 million to combat genetic killer of infants & toddlers
7. US cancer researchers launch first American-Israeli cancer conference
8. USC dental researchers develop first test for predicting cavities in children
9. Young blood revives aging muscles, Stanford researchers find
10. Uric acid may help reduce effects of spinal cord injury, Jefferson researchers find
11. Age should not be a factor in determining heart transplantation eligibility, researchers say

Post Your Comments:
(Date:11/21/2014)... VogueQueen has released 18 new beach wedding ... coming holiday season. People who register at VogueQueen.com now ... The beach wedding dresses from VogueQueen.com have been very ... the premium quality fabrics and dedicated craftsmanship. These products ... environment, they would bring more fun to a lady’s ...
(Date:11/21/2014)... 2014 Midway through the research period ... (AIS) annual Directory of Health Plans, preliminary data shows ... of Health Plans is a comprehensive resource with enrollment ... the U.S. The 2015 edition will be ... Directory and Databases Division, the company’s exclusive in-house research ...
(Date:11/21/2014)... 2014 TruDenta, the creator of a ... and other jaw-related symptoms, has reported a nationwide rise ... head pain, neck pain, TMJ (temporomandibular joint) disorder, jaw ... have seen a 52% increase in the number of ... 300 doctors and their teams in 47 states are ...
(Date:11/21/2014)... 2014 Recently, DressVe.com , a renowned ... announced a new collection of fashion accessories. Furthermore, the company ... up to 95% off, on all its fashion items. Also, ... to the CEO of the company, their wedding dresses and ... now available at greatly discounted rates. , The CEO ...
(Date:11/21/2014)... November 21, 2014 Recently, TideStore.com, a ... accessories, has announced its special offer TideStore Thanksgiving ... items at TideStore.com are now provided with big discounts. ... 25. People can enjoy an extra 10% discount with ... their email addresses and have opportunities to win free ...
Breaking Medicine News(10 mins):Health News:Beach Wedding Dresses on Sale for the Coming Holiday Season at VogueQueen.com 2Health News:Data from Atlantic Information Services’s Forthcoming Directory Shows Volatility in U.S. Health Care Market 2Health News:National Rise In Patients Seeking Headache Relief 2Health News:DressVe.com Announces Its 2014 Special Friday Sales 2Health News:Thanksgiving Sales from TideStore.com 2
(Date:11/21/2014)... November 2014 Clementia ... gegeben, dass die Europäische Arzneimittel-Agentur (European ... als Orphan-Medizinprodukt an Palovarotene vergeben hat, ... Behandlung von Fibrodysplasia ossificans progressiva (FOP). ... genetische Krankheit, die von schmerzhaften, wiederkehrenden ...
(Date:11/21/2014)... DUBLIN, Ohio and MELVILLE, N.Y. ... (NYSE: CAH ), one of the world,s ... (NASDAQ: HSIC ), the world,s largest provider ... animal health and medical practitioners, today announced that the ... provide one of the most comprehensive service and product ...
(Date:11/21/2014)... YORK , Nov. 20, 2014  Market research firm ... the "Year of The Buy, in the medical device ... for medical devices will produce just 3% growth this ... actions, including acquisitions of product lines and entrance by ... annual survey of medical devices, The Global Market ...
Breaking Medicine Technology:Clementia Pharmaceuticals erhält EMA-Kennzeichnung als Orphan-Medizin für Palovarotene zur Behandlung von Fibrodysplasia ossificans progressiva 2Clementia Pharmaceuticals erhält EMA-Kennzeichnung als Orphan-Medizin für Palovarotene zur Behandlung von Fibrodysplasia ossificans progressiva 3Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 2Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 3Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 4Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 5Kalorama: 2014 The "Year of The Buy" in Medical Device Industry 2
Cached News: