HOME >> MEDICINE >> NEWS
UCSD researchers determine fatty liver disease different in obese children than in adults

Potentially life-threatening non-alcoholic fatty liver disease (NAFLD) in obese children has distinct characteristics, often different from those found in adults, according to a University of California, San Diego (UCSD) School of Medicine study led by Jeffrey Schwimmer, M.D., assistant professor of pediatrics.

Presented May 18, 2004 at the annual Digestive Disease Week meeting in New Orleans, the largest international gathering of gastroenterology and hepatology physicians, surgeons and researchers, the findings describe a new paradigm for diagnosis of this common condition found in obese children and offer the potential for improved care.

Between 1997 and 2003, the investigators identified 100 children ages 2 to 18 with biopsy-proven NAFLD. They found clearly different patterns and locations of liver scarring and inflammation in children as compared to that typically seen in adults. Focusing on the most severe form of NAFLD, called nonalcoholic steatohepatitis, or NASH, the researchers divided it into two types which they named Type 1 (the classic adult pattern) and Type 2 (a proposed pediatric pattern).

Specifically, the researchers found that Type 2 NASH was more than three times as common as Type 1 NASH in children. Advanced liver scarring and cirrhosis were seen only in children with Type 2 NASH. In addition, they found that boys were more likely than girls to have Type 2 NASH and less likely to have Type 1. Type 2 NASH was also more common in children of non-white race or Hispanic ethnicity.

Schwimmer, director of the Fatty Liver Clinic at Children's Hospital in San Diego, noted that "many obese children will already have NAFLD without any symptoms. Our data suggest particular groups of children at risk for advanced disease. We believe that the different injury patterns in children suggests differences in causation and potentially treatment and outcome. Additionally, we speculate that Type 2 NASH may also occur in ad
'"/>

Contact: Sue Pondrom
spondrom@ucsd.edu
619-543-6163
University of California - San Diego
18-May-2004


Page: 1 2

Related medicine news :

1. Indiana University researchers closer to helping hearing-impaired using stem cells
2. Protein that helps skin cancer spread identified by Stanford researchers
3. US life expectancy about to decline, researchers say
4. Gene for age-related macular degeneration discovered by Yale researchers
5. Dartmouth researchers find where musical memories are stored in the brain
6. Columbia researchers receive $3 million to combat genetic killer of infants & toddlers
7. US cancer researchers launch first American-Israeli cancer conference
8. USC dental researchers develop first test for predicting cavities in children
9. Young blood revives aging muscles, Stanford researchers find
10. Uric acid may help reduce effects of spinal cord injury, Jefferson researchers find
11. Age should not be a factor in determining heart transplantation eligibility, researchers say

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... ... , ... Looking for a last-minute Valentine’s Day gift for the special someone ... massage, whether administered by a professional masseuse or a loved one, can bring substantial ... Multiple Specialties in Podiatry (ABMSP) has taken the upcoming Valentine’s Day as an ...
(Date:2/5/2016)... , ... February 05, 2016 , ... ... PROSHRED franchises from across the country gathered at the La Valencia Hotel in ... performers. PROSHRED Chicago was named the year’s most outstanding franchise, walking away ...
(Date:2/5/2016)... ... February 05, 2016 , ... ... the 2015 Best in KLAS: Software & Services for HIT Implementation Support & ... KLAS report independently ranks vendor performance by healthcare executives, managers and clinicians representing ...
(Date:2/5/2016)... ... February 05, 2016 , ... Colorize is a ... drop zone to the next using Colorize's dynamic moving camera. Colorize is perfect for ... includes a 3D slideshow environment with 1 to 5 focus points per scene, stage ...
(Date:2/5/2016)... ... 05, 2016 , ... Calls Blacklist has just been updated by mobile app ... the developer has fixed known bugs within the app. Calls Blacklist allows its users ... not consuming any of their device’s battery power or memory. It provides a powerful ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... 5, 2016 --> ... report "Fetal (Labor & Delivery) and Neonatal Care Equipment ... Pulse Oximeter, Phototherapy/Jaundice Management Devices, CPAP, Capnograph, & Resuscitator) ... report studies the global market over the forecast period ... USD 6.28 Billion in 2015 and is poised to ...
(Date:2/5/2016)... PUNE, India , February 4, 2016 ... , Spain , UK, and Israel ... of Type 1, 2, and 3 GD, segmented by age and sex ... and PhD-level epidemiologists. The EpiCast Report is in-depth, high quality, transparent and ... France , Germany , ...
(Date:2/4/2016)... , Feb. 4, 2016  Edwards Lifesciences Corporation ... innovations for structural heart disease and critical care monitoring, ... share repurchase (ASR) agreement with Morgan Stanley & Co. ... This repurchase is part of the Company,s previously authorized ... Company,s common stock.  --> ...
Breaking Medicine Technology:
Cached News: