HOME >> MEDICINE >> NEWS
UCSD researchers determine fatty liver disease different in obese children than in adults

Potentially life-threatening non-alcoholic fatty liver disease (NAFLD) in obese children has distinct characteristics, often different from those found in adults, according to a University of California, San Diego (UCSD) School of Medicine study led by Jeffrey Schwimmer, M.D., assistant professor of pediatrics.

Presented May 18, 2004 at the annual Digestive Disease Week meeting in New Orleans, the largest international gathering of gastroenterology and hepatology physicians, surgeons and researchers, the findings describe a new paradigm for diagnosis of this common condition found in obese children and offer the potential for improved care.

Between 1997 and 2003, the investigators identified 100 children ages 2 to 18 with biopsy-proven NAFLD. They found clearly different patterns and locations of liver scarring and inflammation in children as compared to that typically seen in adults. Focusing on the most severe form of NAFLD, called nonalcoholic steatohepatitis, or NASH, the researchers divided it into two types which they named Type 1 (the classic adult pattern) and Type 2 (a proposed pediatric pattern).

Specifically, the researchers found that Type 2 NASH was more than three times as common as Type 1 NASH in children. Advanced liver scarring and cirrhosis were seen only in children with Type 2 NASH. In addition, they found that boys were more likely than girls to have Type 2 NASH and less likely to have Type 1. Type 2 NASH was also more common in children of non-white race or Hispanic ethnicity.

Schwimmer, director of the Fatty Liver Clinic at Children's Hospital in San Diego, noted that "many obese children will already have NAFLD without any symptoms. Our data suggest particular groups of children at risk for advanced disease. We believe that the different injury patterns in children suggests differences in causation and potentially treatment and outcome. Additionally, we speculate that Type 2 NASH may also occur in ad
'"/>

Contact: Sue Pondrom
spondrom@ucsd.edu
619-543-6163
University of California - San Diego
18-May-2004


Page: 1 2

Related medicine news :

1. Indiana University researchers closer to helping hearing-impaired using stem cells
2. Protein that helps skin cancer spread identified by Stanford researchers
3. US life expectancy about to decline, researchers say
4. Gene for age-related macular degeneration discovered by Yale researchers
5. Dartmouth researchers find where musical memories are stored in the brain
6. Columbia researchers receive $3 million to combat genetic killer of infants & toddlers
7. US cancer researchers launch first American-Israeli cancer conference
8. USC dental researchers develop first test for predicting cavities in children
9. Young blood revives aging muscles, Stanford researchers find
10. Uric acid may help reduce effects of spinal cord injury, Jefferson researchers find
11. Age should not be a factor in determining heart transplantation eligibility, researchers say

Post Your Comments:
(Date:10/31/2014)... Rice University researchers have mapped how information flows through ... metastatic. The research reveals a common pattern in the ... form new tumors. Researchers say the commonality may open ... genetic switches that cancer must flip to form both ... of the main players in cancer metastasis. , "Cells ...
(Date:10/31/2014)... The Memory Healer review published by DailyGossip.org reveals ... father suffered from Alzheimer's disease. , In fact, Alexander ... father's disease. His father pointed a gun and shot him ... the author of this method understood that he needed to ... Healer program is based on years of research. The author ...
(Date:10/31/2014)... Oaks, CA (PRWEB) October 31, 2014 ... tummy also has amazing health effects for practitioners. ... created by a Doctor of Science and Movement ... through his dedication to pelvic floor reeducation that ... of urinary incontinence, Diastasis Recti, Prolepses, etc. , ...
(Date:10/31/2014)... 2014 Activz Whole-Food Nutrition ... line offering natural silver healing support† in liquid ... century, silver has been used to support natural healing, ... is the most advanced version available. This latest formula, ... structure that supports the existing healing mechanisms in the ...
(Date:10/31/2014)... apnea may make it hard for you to remember simple ... your house keys, a small study suggests. Tests on ... -- called spatial memory -- was impaired when sleep apnea ... of sleep weren,t affected. REM sleep is the deepest level ... for the first time that sleep apnea, an increasingly common ...
Breaking Medicine News(10 mins):Health News:Decoding the emergence of metastatic cancer stem cells 2Health News:Decoding the emergence of metastatic cancer stem cells 3Health News:"Memory Healer" Review Reveals a New Natural Remedy Guide for Managing Memory Loss 2Health News:Super Models and European Celebrities’ Secret Flat Tummy System Comes to America 2Health News:Super Models and European Celebrities’ Secret Flat Tummy System Comes to America 3Health News:New Collection of Nano-particle Natural Silver Products by Activz Whole-Food Nutrition 2Health News:New Collection of Nano-particle Natural Silver Products by Activz Whole-Food Nutrition 3Health News:New Collection of Nano-particle Natural Silver Products by Activz Whole-Food Nutrition 4Health News:Sleep Apnea May Steal Some of Your Memory: Study 2
(Date:10/31/2014)... , Oct. 31, 2014 Imago ... today announced a $26.5 million Series A financing ... firm founded by a team of accomplished investment ... investors participating in the round include Frazier Healthcare, ... Representatives from Clarus Ventures and Frazier Healthcare will ...
(Date:10/31/2014)... , October 31, 2014 ... Corporation (NASDAQ: CELG ), Bristol-Myers Squibb Co. ... UNH ), Sanofi SA (NYSE: ... members receive these notes ahead of publication. To reserve ... . , ,-- ,Celgene Corporation Research Reports ,On October ...
(Date:10/31/2014)... Calif. , Oct. 31, 2014 ThynkWare ... sclerosis (ALS) patients initiate text and email messages using ... a patent-pending technology invented by ThynkWare,s founder, Duane ... on a smartphone device. This technology allows users to ... only the power of thought. ThynkWare provides ...
Breaking Medicine Technology:Imago BioSciences Announces $26.5 Million Financing Led by Clarus Ventures 2Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 2Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 3Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 4Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 5Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 6ThynkWare Speech Helps Those with ALS and Locked-In Syndrome Translate Thought to Speech on Their Smartphone Devices 2
Cached News: