HOME >> MEDICINE >> NEWS
UCSD researchers determine fatty liver disease different in obese children than in adults

Potentially life-threatening non-alcoholic fatty liver disease (NAFLD) in obese children has distinct characteristics, often different from those found in adults, according to a University of California, San Diego (UCSD) School of Medicine study led by Jeffrey Schwimmer, M.D., assistant professor of pediatrics.

Presented May 18, 2004 at the annual Digestive Disease Week meeting in New Orleans, the largest international gathering of gastroenterology and hepatology physicians, surgeons and researchers, the findings describe a new paradigm for diagnosis of this common condition found in obese children and offer the potential for improved care.

Between 1997 and 2003, the investigators identified 100 children ages 2 to 18 with biopsy-proven NAFLD. They found clearly different patterns and locations of liver scarring and inflammation in children as compared to that typically seen in adults. Focusing on the most severe form of NAFLD, called nonalcoholic steatohepatitis, or NASH, the researchers divided it into two types which they named Type 1 (the classic adult pattern) and Type 2 (a proposed pediatric pattern).

Specifically, the researchers found that Type 2 NASH was more than three times as common as Type 1 NASH in children. Advanced liver scarring and cirrhosis were seen only in children with Type 2 NASH. In addition, they found that boys were more likely than girls to have Type 2 NASH and less likely to have Type 1. Type 2 NASH was also more common in children of non-white race or Hispanic ethnicity.

Schwimmer, director of the Fatty Liver Clinic at Children's Hospital in San Diego, noted that "many obese children will already have NAFLD without any symptoms. Our data suggest particular groups of children at risk for advanced disease. We believe that the different injury patterns in children suggests differences in causation and potentially treatment and outcome. Additionally, we speculate that Type 2 NASH may also occur in ad
'"/>

Contact: Sue Pondrom
spondrom@ucsd.edu
619-543-6163
University of California - San Diego
18-May-2004


Page: 1 2

Related medicine news :

1. Indiana University researchers closer to helping hearing-impaired using stem cells
2. Protein that helps skin cancer spread identified by Stanford researchers
3. US life expectancy about to decline, researchers say
4. Gene for age-related macular degeneration discovered by Yale researchers
5. Dartmouth researchers find where musical memories are stored in the brain
6. Columbia researchers receive $3 million to combat genetic killer of infants & toddlers
7. US cancer researchers launch first American-Israeli cancer conference
8. USC dental researchers develop first test for predicting cavities in children
9. Young blood revives aging muscles, Stanford researchers find
10. Uric acid may help reduce effects of spinal cord injury, Jefferson researchers find
11. Age should not be a factor in determining heart transplantation eligibility, researchers say

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/22/2017)... ... September 22, 2017 , ... "Success Files," a short- ... Alzheimer’s. Alzheimer’s is a disease estimated to affect the lives of more than ... the Alzheimer’s Association, a leading voice in the fight for cure and research ...
(Date:9/22/2017)... ... September 22, 2017 , ... ... and create life. Although frozen embryos have a slight statistical advantage for live ... freezing is a wonderful opportunity for women undergoing medical treatment or who are ...
(Date:9/21/2017)... ... September 21, 2017 , ... SABRE is raising awareness about personal ... to the end of November. , The Chicago, Illinois, based self-defense brand has been ... them about the ease of taking their personal safety into their own hands. , ...
(Date:9/21/2017)... ... September 21, 2017 , ... Bill Howe Plumbing’s mission is to create an ... to the community. For over 37 years, they have operated with their mission at ... in San Diego. They were chosen as the Best San Diego plumber in ...
(Date:9/21/2017)... ... September 21, 2017 , ... Japanese Zen artist couple, Fumie and Kentaro ... 7th and 8th October at Miranda Kuo Gallery on Lower East Side, NYC. This ... Zen Kodo mat. Wanderlust , one of the largest US yoga online media ...
Breaking Medicine News(10 mins):
(Date:9/6/2017)...  Medical professionals are expected to continuously ... their patients. Medical simulations offer clinicians the ... Simulation provides a safe method for teaching ... refine techniques and build confidence, without putting ... such as augmented reality, will now provide ...
(Date:9/5/2017)... 5, 2017  Xyntek Inc. has announced another milestone in their continued growth ... to meet the growing demands of customer engagements regionally.  ... Xyntek's new Midwest office is located at 318 West Adams Street, Suite ... Xyntek's ... ...
(Date:9/1/2017)... , Sept. 1, 2017  Explorers Like Us ( https://explorerslikeus.com/ ... greatest aural experiences — and deliver these experiences as part ... help people feel and heal better. ... While nothing beats a walk, jog ... your mind, Life Environments™ is the next best thing when ...
Breaking Medicine Technology:
Cached News: