HOME >> MEDICINE >> NEWS
UCSD's Victor Nizet, M.D., receives Pediatric Infectious Diseases Award

Victor Nizet, M.D., a University of California, San Diego (UCSD) assistant professor of pediatrics and attending physician, Children's Hospital, San Diego, has received the Pediatric Infectious Diseases Young Investigator Award from the national Pediatric Infectious Diseases Society.

Presented to Nizet at the Society's annual meeting last month in Baltimore, the award recognizes young physicians who have made outstanding contributions in clinical or basic research in pediatric infectious diseases.

Nizet Investigates bacteria that produce disease in children, with a particular focus on the pathogens group A and group B streptococcus (strep). Group A strep is the cause of strep throat and invasive infections including necrotizing fasciitis ("flesh-eating disease"), while group B strep is the leading cause of serious bacterial infections in newborn infants. Using molecular genetic methods, Nizet and colleagues discovered different sets of genes in each bacteria that produce potent toxins capable of injuring human cells.

"Our goal was to prove that specific genes were necessary and sufficient for the production of these toxins," Nizet said. "We did this by removing the genes from the strep bacteria and found that the bacteria no longer produced the toxin. The toxin-deficient strains were then found to lack the ability to produce injury or disease in animal models of human strep infection."

The Nizet group also took the genes they had identified and cloned them into other bacteria that normally don't produce toxins. With the new genes added, the benign bacteria became a toxin-producing factory.

As a result of Nizet's findings, researchers now have a better understanding of the two strep bacteria, which he believes will aid in the search for new treatments and disease prevention that specifically target the newly identified toxins.

In addition to these studies, the Nizet group investigates two additional areas anti
'"/>

Contact: Sue Pondrom
spondrom@ucsd.edu
619-543-6163
University of California - San Diego
19-Jun-2002


Page: 1 2

Related medicine news :

1. UCSDs Dr. Leon Thal to receive Potamkin Prize, one of neurosciences highest honors
2. Michelle Trudeau wins 2004 Victor Cohn Prize for Excellence in Medical Reporting
3. Jeffrey S. Flier, M.D., elected to Institute of Medicine
4. William Cohn, M.D., of Beth Israel Deaconess Medical Center, receives the 2000 Distinguished Inventor Award
5. Statement from Claude Lenfant, M.D., NHLBI Director, on Trends in Hypertension
6. UIC professor receives international humanitarian award
7. Mailman School of Public Health receives Manhattan Tobacco Cessation Center grant
8. Epidemiologist Trichopoulos receives $5.8 million Department of Defense Innovator Award
9. GlaxoSmithKline receives unanimous favorable recommendation by FDA Advisory Committee for Boostrix
10. NYU Child Study Center receives grant from the American Red Cross September 11 recovery program
11. Northwestern Memorial Hospital receives $10 million commitment to support preeminent heart program

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: UCSD Victor Nizet receives Pediatric Infectious Diseases Award

(Date:4/18/2014)... by Northwestern Medicine scientists could lead to potential new ... people with scleroderma. , Fibrosis, or scarring, is ... the skin and lungs can lead to serious organ ... for new therapeutic options centers on findings made by ... identified the role that a specific protein plays in ...
(Date:4/17/2014)... first genetic variant specifically associated with the risk ... 10-15 per cent of all breast cancer cases. ... cancer sub-type, called invasive lobular carcinoma, gives researchers ... particular kind of breast cancer, which can be ... (Thursday) in the journal PloS Genetics , ...
(Date:4/17/2014)... published today in PLOS Pathogens , children who ... common can mount an immune response to infection with ... bouts of high fever and illness and partially control ... findings may help researchers develop future interventions that prevent ... , Each year, approximately 200 million cases of malaria ...
(Date:4/17/2014)... Two recent papers by a University of ... help scientists develop treatments or vaccines for Dengue ... and other disease-causing flaviviruses. , Jeffrey S. Kieft, ... at the School of Medicine and an early ... and colleagues recently published articles in the scholarly ...
(Date:4/17/2014)... A Northwestern University synthetic biology team has created ... create programmable therapeutics that could travel the body ... disease. , Engineering cell-based, biological devices that monitor ... in clinical synthetic biology. However, no existing technology ... a patient,s physiological state and respond in a ...
Breaking Medicine News(10 mins):Health News:New clues on tissue scarring in scleroderma 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 3Health News:Study sheds light on how the immune system protects children from malaria 2Health News:CU researchers discover target for treating dengue fever 2Health News:Building 'smart' cell-based therapies 2
(Date:1/15/2014)... 2014  Zafgen, Inc., a leading biopharmaceutical company dedicated ... patients, today announced initial results from its Phase ... methionine aminopeptidase 2 (MetAP2), in patients with Prader-Willi ...  These results showed improvements in body weight, hunger-related ...
(Date:1/14/2014)... InformEx, North America,s leading business partnering ... the 30 th edition of its annual conference at ... January 21-24. (Logo: http://photos.prnewswire.com/prnh/20131028/NY05330LOGO-a ) ... and specialty chemical companies will take part in the conference, ...
(Date:1/14/2014)... Jan. 14, 2014 Animal Emergency Critical Care, a LifeCentre partner ... Virginia is the first in Loudoun County ... Dr. Susan M. Barnes , Medical Director, is ... husband, Dr. Cole Taylor , are avid scuba divers. "As ...
Breaking Medicine Technology:Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 2Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 3Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 4Media Advisory: InformEx 2014 Events & Speaker Lineup for 30th Edition Conference in Miami Beach 2Hyperbaric Veterinary Medicine (hvm) Announces Animal Emergency Critical Care Installs A Small Animal Hyperbaric Chamber 2
Cached News: