HOME >> MEDICINE >> NEWS
UNC-CH wins $42.1 million federal contract to study drugs for schizophrenia and Alzheimer's

CHAPEL HILL, N.C. - The University of North Carolina at Chapel Hill has won a $42.1 million federal contract to determine the effectiveness and safety of a new class of anti-psychotic drugs for treating people with schizophrenia and those with psychotic and disruptive behaviors associated with Alzheimer's disease.

The contract, announced today by the National Institute of Mental Health (NIMH) in Bethesda, Md., is the largest ever awarded by the federal agency. It places the university in charge of a multi-center, five-year effort aimed at definitively determining the value of the new class of atypical anti-psychotic drugs represented by clozapine, risperidone, olanzapine and quetiapine.

"This research will make an unparalleled contribution to defining the clinical role of the new anti-psychotics," said Dr. Steven E. Hyman, director of the NIMH. "It will provide reliable data on the efficacy of these atypical medications in relieving psychotic symptoms of schizophrenia and Alzheimer's disease, and will gauge their effectiveness in terms of broader outcomes - such as adherence to treatment, ability to work, social functioning and quality of life."

Now on the market, these drugs are proven effective in carefully controlled clinical studies typically co-sponsored by drug companies. The drugs differ from other anti-psychotic agents in that they act on multiple cell receptor sites in the brain, including receptors for dopamine, serotonin and norepinephrine, instead of just dopamine.

However, the new drugs cost more than 10 times that of the old medications and questions remain about their effectiveness in the real world and whether they are worth the higher price.

"The NIMH wants to get definitive and objective results in terms of their effectiveness, results of significant magnitude in real world settings that can inform public health policy," said Dr. Jeffrey A. Lieberman, professor of psychiatry, pharmacology and radiology at UNC-CH
'"/>

Contact: Lynn Wooten
LWooten@unch.unc.edu
919-966-6046
University of North Carolina School of Medicine
13-Oct-1999


Page: 1 2

Related medicine news :

1. UNC-CH School of Social Work receives grant to prevent violence
2. CDC funds will enable UNC-CH to help minimize domestic violence in flood areas
3. UNC-CH to lead $34 million effort to see if girls can become more fit
4. UNC-CH public health specialists confirm Norwalk-like virus caused Seawell illnesses
5. UNC-CH study finds N.C. outpatient heart rehabilitation programs mostly under-used
6. UNC-CH, Duke AIDS experts, patients to update epidemic, describe new support
7. 90 high schools will participate in UNC-CH head injury study
8. National Cancer Institute awards UNC-CH $5 million for unique prostate cancer studies
9. Annual UNC-CH study shows state gaining health providers, but big imbalances remain
10. UNC-CH nutrition expert says nation should regulate some diet supplements
11. National Cancer Institute to support statewide UNC-CH colon cancer study

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/11/2018)... ... ... Dr. Siavash Eftekhari, Oral and Maxillofacial Surgeon at Monarch Dental® in ... to deliver dental care in impoverished communities. Along with a team of fellow ... to help deliver care to over 550 individuals in need. , This outreach was ...
(Date:8/11/2018)... ATLANTA (PRWEB) , ... August 11, 2018 , ... ... winner of a Silver Stevie® Award in the Executive of the Year-Business category ... the world’s premier business awards program. All individuals and organizations worldwide – public ...
(Date:8/9/2018)... ... August 09, 2018 , ... ... by simplifying medication adherence monitoring with Smart-pill bottle and mobile applications, DoseSmart ... the App Orchard. , The DoseSmart medication management and medication adherence platform ...
(Date:8/7/2018)... ... August 07, 2018 , ... Sussex Vision Center, a multi-site optometry practice ... Sussex, OD, founded the practice in Coldwater, and over the last three decades has ... to offer comprehensive eye health services for patients of all ages. , “I ...
(Date:8/3/2018)... ... August 03, 2018 , ... On August 2, 2018 ... proceedings. Mark Sadaka of Sadaka Associates, LLC has been litigating Zostavax injuries ... before the Judicial Panel on Multidistrict Litigation for the thousands of people injured by ...
Breaking Medicine News(10 mins):
(Date:8/3/2018)... ... August 03, 2018 , ... Flexefits, a pioneer in direct -pay, direct access ... allowing participants in Direct Primary Care arrangements to keep HSA eligibility and permit DPC ... individual and $300 per family per month.) , “We are very pleased to see ...
(Date:8/2/2018)... ... ... UMD Professor Utpal Pal leads a team of investigators across multiple institutions ... of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), ... contribute to the spread of major diseases like Lyme disease. Pal is the project ...
(Date:8/2/2018)... ... August 02, 2018 , ... ... with customer relationship management (CRM), patient experience and provider communication solutions for ... Program for Health Information Service Providers (HISPs). DirectTrust is a ...
Breaking Medicine Technology:
Cached News: