HOME >> MEDICINE >> NEWS
USC dental researchers develop first test for predicting cavities in children

A simple saliva test can predict for the first time whether children will get cavities, how many cavities they will get and even which teeth are most vulnerable, University of Southern California researchers say.

Developed by a USC School of Dentistry team led by professor Paul Denny, the test quantifies the genetic component of tooth decay (caries).

Dentists have long known that even in areas with fluoridation and good oral hygiene education, some people just have bad teeth. The USC test spots the risk early, when something can be done about it.

"When we apply this to young children, it allows us to predict what might be their future caries history - the number of cavities that they'll get by, say, their late twenties or early thirties," Denny said.

The Caries Assessment and Risk Evaluation (CARE) test measures the relative proportions in saliva of different types of sugar chains, known as oligosaccharides. The same sugar chains are present on tooth surfaces.

The effect of sugar chains on the tooth's ability to resist disease is analogous to the effect of "good" and "bad" cholesterol on blood vessels. "Good" sugar chains tend to repel the bacteria that cause cavities, while "bad" sugar chains allow the bacteria to bond to a tooth and start the decay process.

Unlike cholesterol, humans' sugar chain makeup is 100 percent genetically determined and cannot be changed. The USC researchers found that the sugar chain makeup in saliva can predict a child's future cavity history to plus or minus one cavity with greater than 98 percent confidence.

Children at the far ends of the spectrum - those with exceptionally weak or strong oral hygiene and nutritional habits - may develop more or fewer cavities than the test predicts. Bad habits may cause tooth decay, but researchers caution against extreme measures: completely eliminating sugar has not been shown to prevent cavities, and over-brushing can cause enamel erosion.
'"/>

Contact: Carl Marziali
marziali@usc.edu
213-740-4751
University of Southern California
18-Feb-2005


Page: 1 2 3

Related medicine news :

1. Finances, not having a dentist are primary barriers to seniors receiving needed dental care
2. Routine dental panoramic X-rays not necessary, study shows
3. Research fills dental need
4. Oral cancer survey from Case dental school shows dental hygienists role in catching cancer
5. HIV-positive U.S. military personnel accidentally vaccinated against smallpox
6. Experience is more effective than classroom learning in changing age bias in dental students
7. Making the case for a dental caries vaccine
8. Older patients need special attention in the dental chair
9. Incidental PET findings may reveal undetected cancer
10. Smokers may want to kick butt before dental procedures
11. Model dental school curriculum to address disparities in oral health care

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/28/2020)... ... February 28, 2020 , ... In what has become the most professional ... in the 15th Annual Best of Long Island (BOLI) 2020. , For the past ... six years ‘Best Ophthalmologist’, and for the past three years Samuel Baharestani, MD, FACS ...
(Date:2/28/2020)... ... February 28, 2020 , ... The Quinism ... calling on GSK to take appropriate action to protect the health of asymptomatic ... the U.S. Prescribing Information for Krintafel®, to better emphasize that the drug is ...
(Date:2/28/2020)... ... 2020 , ... BenefitScape, a leader in ACA compliance reporting ... in connection with new legislation called the New Jersey Health Insurance Market Preservation ... obtain health insurance, have a valid exemption, or pay a penalty called the ...
(Date:2/26/2020)... ... February 26, 2020 , ... The epilepsy team at ... that helps pinpoint the origin of epileptic seizures on a patient. , ... Robotized Surgical Assistant, or ROSA. With assistance from the robot, neurosurgeons only need ...
(Date:2/26/2020)... ... 2020 , ... RosettaHealth , an innovative and secure, ... Worklflows solution, which will be showcased at HIMSS20 in booth #5389. , The ... workflows to scenarios in days using a collection of pre-built components that quickly ...
Breaking Medicine News(10 mins):
(Date:2/28/2020)... ... February 27, 2020 , ... ProMach , a ... named as the company’s new Senior Vice President for its Pharma Business Line. ... oversee operations and commercial activity for ProMach’s Pharma product brands including NJM and ...
(Date:2/28/2020)... ... , ... At the VA Maryland Health Care System, veterans can virtually meet ... VA Video Connect application. Since its rollout in July 2019, the VA Video Connect ... appointments. The VA Video Connect app has proven to be a special benefit for ...
(Date:2/26/2020)... , ... February 26, 2020 , ... SGF is the ... and personalized fertility care for over two decades. With seven locations in Northern Virginia, ... total to 13 reproductive endocrinologists and 1 reproductive urologist. SGF Fairfax’s lab director recently ...
Breaking Medicine Technology:
Cached News: