HOME >> MEDICINE >> NEWS
Ulcer bacteria linked to strokes

DALLAS, July 9 Potent strains of ulcer-causing bacteria may play a key role in certain kinds of stroke, researchers report in today's rapid access issue of Circulation: Journal of the American Heart Association.

For the first time, researchers have found that specific strains of Helicobacter pylori (H. pylori) were much more prevalent in the blood of patients who have suffered an atherosclerotic stroke, says lead author Antonio Pietroiusti, M.D., a professor of internal medicine at Tor Vergata University in Rome.

Some studies have linked H. pylori with inflamed artery walls and arterial lesions, including stroke caused by narrowing of the arteries due to atherosclerosis.

H. pylori causes ulcers in the stomach. In large arteries leading to the brain, the researchers report that cytotoxin-producing strains of the bacteria appear to aggravate an already risky environment. The cytotoxin-associated gene-A (CagA) makes strains of H. pylori virulent and especially damaging to arteries. Cytotoxins attack cells, causing tissue inflammation and ultimately lesions. By attacking vulnerable areas of the artery wall, they cause inflammation and swelling, further restricting blood flow and increasing the chance of stroke.

Researchers compared different strains of H. pylori in the bloodstream of 138 patients with large-vessel stroke (group A); 61 patients with cardioembolic stroke (group B); and 151 healthy volunteers. Extensive atherosclerotic changes cause large vessel strokes, says Pietroiusti. Cardioembolic strokes are caused by abrupt blockage of a cerebral artery by a clot that travels to the brain.

Prevalence of H. pylori infection among patients with large-vessel, , and normal controls was about the same. However, the presence of CagA-positive strains was significantly higher in large-vessel stroke patients than the cardioembolic stroke group 42.8 percent versus 19.7 percent. It was also higher than those of the controls 17.9 per
'"/>

Contact: Bridgette Mc Neill
bridgette.mcneill@heart.org
214-706-1135
American Heart Association
8-Jul-2002


Page: 1 2

Related medicine news :

1. Ulcer Drug Linked To Birth Defects
2. Oral bacteria may predict pregnancy outcomes
3. Study finds direct association between cardiovascular disease and periodontal bacteria
4. Substance protects resilient staph bacteria
5. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
6. Bacteria-killing vs. bacteria-inhibiting drugs in treating infections
7. Patients undergoing weight loss surgery have high rates of H pylori bacteria
8. Outbreak of skin infections sheds light on risk factors for bacterial resistance
9. Popular chewing gum eliminates bacteria that cause bad breath
10. Antibiotic resistant bacteria frequently transmitted between intensive care patients
11. New weapon to combat resistant bacteria

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Ulcer bacteria linked strokes

(Date:10/30/2014)... have to be at least 2 years old to ... no official U.S. guidance exists other than the general ... breastfeed for at least the first six months. , ... That,s the question that motivated researchers at the University ... study the eating patterns of American infants at 6 ...
(Date:10/30/2014)... A mathematical model developed by NIH grantees predicts that ... prevent HIV infection via vaginal sex, whereas just two ... via anal sex. This finding helps explain why two ... in women failed to show efficacy. Participants in the ... Truvada and tenofovir (another antiretroviral) for HIV prevention were ...
(Date:10/30/2014)... 30, 2014 Timothy, InstaKNOT’s ... Beach firefighters, showing that you are never too young ... met firefighters Tracey and Carl at the 2013 Santa ... the Pompano Beach Chamber of Commerce. Tracey gave Timothy ... letting Timothy wear his real fireman’s hat, and extending ...
(Date:10/30/2014)... Don Allred Insurance, a leading provider of ... North Carolina residents, is excited to announce the Grand ... Mall. The new branch has been up and running ... all facets of the insurance selection process from quote ... Allred couldn’t be happier with the timing of this ...
(Date:10/30/2014)... Five months after their expansion, the AV ... branding and a website to accompany their recent change ... promotion to name partner earlier this year, Hodgkinson Street ... name and better reflect their combined litigation expertise. As ... to implement new branding reflects Hodgkinson Street Mepham’s collaborative ...
Breaking Medicine News(10 mins):Health News:What do American babies eat? A lot depends on Mom's socioeconomic background 2Health News:What do American babies eat? A lot depends on Mom's socioeconomic background 3Health News:Model by NIH grantees explains why HIV prevention dosing differs by sex 2Health News:4-year-old InstaKNOT CEO Honors Local Firefighters with Community Support 2Health News:4-year-old InstaKNOT CEO Honors Local Firefighters with Community Support 3Health News:4-year-old InstaKNOT CEO Honors Local Firefighters with Community Support 4Health News:Allred Insurance Satellite Office Grand Opening 2Health News:Hodgkinson Street Mepham Rebrands 2
(Date:10/30/2014)... , Oct. 30, 2014 Today Eli Lilly ... of its long-standing technology transfer program to increase the ... in 2003, the effort included Lilly donating manufacturing technology ... China , India ... South Africa – all MDR-TB ,hot spots., ...
(Date:10/27/2014)... 27, 2014 Research and Markets has ... 2014-2018" report to their offering. H1N1 ... a variant of the swine H1N1 virus, known as H1N1v ... nose, throat, and lungs. H1N1 virus is an RNA virus ... animal species such as humans, swine, birds, seals, and horses. ...
(Date:10/27/2014)... EAST TAUNTON, Mass. , Oct. 27, 2014 /PRNewswire/ ... the $15 billion global hip and knee replacement device market, ... and knee replacement technology at the American Association of ... the Sheraton Dallas Hotel in Dallas, Texas ... is a Bronze corporate partner of the organization. ...
Breaking Medicine Technology:Lilly Shares Insights from Decade-Long Technology Transfer Experience 2Lilly Shares Insights from Decade-Long Technology Transfer Experience 3Lilly Shares Insights from Decade-Long Technology Transfer Experience 4Global H1N1 Vaccines Market 2014-2018: Key Vendors are AstraZeneca, GlaxoSmithKline, Novartis and Sanofi Pasteur 2Global H1N1 Vaccines Market 2014-2018: Key Vendors are AstraZeneca, GlaxoSmithKline, Novartis and Sanofi Pasteur 3OMNIlife science to Exhibit at American Association of Hip and Knee Surgeons 24th Annual Meeting in Dallas November 6-9 2OMNIlife science to Exhibit at American Association of Hip and Knee Surgeons 24th Annual Meeting in Dallas November 6-9 3
Cached News: