Ulcer bacteria linked to strokes

DALLAS, July 9 Potent strains of ulcer-causing bacteria may play a key role in certain kinds of stroke, researchers report in today's rapid access issue of Circulation: Journal of the American Heart Association.

For the first time, researchers have found that specific strains of Helicobacter pylori (H. pylori) were much more prevalent in the blood of patients who have suffered an atherosclerotic stroke, says lead author Antonio Pietroiusti, M.D., a professor of internal medicine at Tor Vergata University in Rome.

Some studies have linked H. pylori with inflamed artery walls and arterial lesions, including stroke caused by narrowing of the arteries due to atherosclerosis.

H. pylori causes ulcers in the stomach. In large arteries leading to the brain, the researchers report that cytotoxin-producing strains of the bacteria appear to aggravate an already risky environment. The cytotoxin-associated gene-A (CagA) makes strains of H. pylori virulent and especially damaging to arteries. Cytotoxins attack cells, causing tissue inflammation and ultimately lesions. By attacking vulnerable areas of the artery wall, they cause inflammation and swelling, further restricting blood flow and increasing the chance of stroke.

Researchers compared different strains of H. pylori in the bloodstream of 138 patients with large-vessel stroke (group A); 61 patients with cardioembolic stroke (group B); and 151 healthy volunteers. Extensive atherosclerotic changes cause large vessel strokes, says Pietroiusti. Cardioembolic strokes are caused by abrupt blockage of a cerebral artery by a clot that travels to the brain.

Prevalence of H. pylori infection among patients with large-vessel, , and normal controls was about the same. However, the presence of CagA-positive strains was significantly higher in large-vessel stroke patients than the cardioembolic stroke group 42.8 percent versus 19.7 percent. It was also higher than those of the controls 17.9 per

Contact: Bridgette Mc Neill
American Heart Association

Page: 1 2

Related medicine news :

1. Ulcer Drug Linked To Birth Defects
2. Oral bacteria may predict pregnancy outcomes
3. Study finds direct association between cardiovascular disease and periodontal bacteria
4. Substance protects resilient staph bacteria
5. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
6. Bacteria-killing vs. bacteria-inhibiting drugs in treating infections
7. Patients undergoing weight loss surgery have high rates of H pylori bacteria
8. Outbreak of skin infections sheds light on risk factors for bacterial resistance
9. Popular chewing gum eliminates bacteria that cause bad breath
10. Antibiotic resistant bacteria frequently transmitted between intensive care patients
11. New weapon to combat resistant bacteria

Post Your Comments:

(Date:6/26/2016)... ... , ... Quality metrics are proliferating in cancer care, and are derived from ... of the beholder, according to experts who offered insights and commentary in the current ... For the full issue, click here . , For the American Society of ...
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified ... be personalized through a fitness app. The fitness app plans to fix the two major ... only offer a one size fits all type program , They don’t eliminate ...
(Date:6/25/2016)... ... ... closing of Bruton Memorial Library on June 21 due to a possible lice infestation, as ... of head lice: the parasite’s ability to live away from a human host, and to ... one in the event that lice have simply gotten out of control. , As lice ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson has ... he has implemented orthobiologic procedures as a method for treating his patients. The ... first doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use ...
(Date:6/24/2016)... ... , ... Those who have experienced traumatic events may suffer from a complex ... as drug or alcohol abuse, as a coping mechanism. To avoid this pain and ... a traumatic event. , Trauma sufferers tend to feel a range of emotions, from ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research ... Devices Global Market - Forecast to 2022" report to ... the treatment method for the patients with kidney failure, it ... excess fluid from the patient,s blood and thus the treatment ... potassium and chloride in balance. Increasing number ...
(Date:6/23/2016)... 23, 2016 Roche (SIX: RO, ROG; OTCQX: ... its Elecsys BRAHMS PCT (procalcitonin) assay as a dedicated ... shock. With this clearance, Roche is the first IVD ... solution for sepsis risk assessment and management. ... and PCT levels in blood can aid clinicians in ...
(Date:6/23/2016)... 2016 Bracket , a leading clinical trial ... clinical outcomes platform, Bracket eCOA (SM) 6.0, at the ... – 30, 2016 in Philadelphia , Pennsylvania.  ... Assessment product of its kind to fully integrate with RTSM, ... eCOA 6.0 is a flexible platform for electronic clinical outcomes ...
Breaking Medicine Technology:
Cached News: