HOME >> MEDICINE >> NEWS
University Of Pittsburgh Cancer Institute Study Confirms Efficacy Of Taxol Regimen In The Treatment Of Advanced Lung Cancer

Los Angeles/Pittsburgh, May 19 -- Results from a large, randomized, phase III study confirmed the efficacy of paclitaxel plus carboplatin in the treatment of non-small cell lung cancer (NSCLC). These data were presented here at the 34th annual meeting of the American Society of Clinical Oncology.

This study was designed to compare paclitaxel/carboplatin to cisplatin/etoposide. The trial enrolled 369 patients with advanced or metastatic NSCLC between May 1995 and July 1996. One hundred seventy-nine patients received cisplatin/etoposide and 190 received paclitaxel/carboplatin. After initial therapy, patients could receive additional chemotherapy.

"Survival in the control arm (cisplatin/etoposide) was unexpectedly higher, and this could be attributable to multiple factors, including second-line chemotherapy with a taxane-based regimen," said Chandra Belani, M.D., associate professor of medicine at the University of Pittsburgh School of Medicine and co-director of the Lung Cancer Program at the University of Pittsburgh Cancer Institute (UPCI).

"Patients in the paclitaxel arm of the study experienced a greater response rate compared to cisplatin/etoposide, 23 percent versus 14 percent respectively," explained Dr. Belani. "Patients who received paclitaxel/carboplatin experienced improvement in quality of life from baseline to third course of chemotherapy."

"In 1998 we are not only talking about first-line therapy NSCLC, but we now need to pursue second-line chemotherapy," concluded Dr. Belani.

The ongoing phase III studies with the paclitaxel/carboplatin regimen being performed by the SWOG, ECOG, CALGB will further substantiate the results of this regimen with NSCLC.

Lung cancer is one the most common cancers in the United States, representing about 15 percent of all cancer cases, or 178,000 new cases in 1997. Lung cancer accounts for over one-fourth (28 percent) of cancer deaths in the Un
'"/>

Contact: Lauren Ward
wardla@a1.isd.upmc.edu
412-624-2607
University of Pittsburgh Medical Center
19-May-1998


Page: 1 2

Related medicine news :

1. Indiana University researchers closer to helping hearing-impaired using stem cells
2. Boston University team finds link between high cholesterol and better cognitive performance
3. University seeks recruits for arthritis study
4. University of Manchester awarded 826k for brain science and mental health research
5. $4 million grant boosts University of Michigan campaign for a new childrens hospital
6. Lead in the environment causes violent crime, reports University of Pittsburgh researcher at AAAS
7. Next generation body scanner launched by the University of Manchester
8. University of Washington joins new Autism Treatment Network to provide better medical services
9. Binghamton University launches microelectronics research center
10. University of Manchester makes made-to-measure skin and bones a reality using inkjet printers
11. RelayHealth selected by Columbia University to link doctors and patients online

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: