University Of Pittsburgh Cancer Institute Study Confirms Efficacy Of Taxol Regimen In The Treatment Of Advanced Lung Cancer

Los Angeles/Pittsburgh, May 19 -- Results from a large, randomized, phase III study confirmed the efficacy of paclitaxel plus carboplatin in the treatment of non-small cell lung cancer (NSCLC). These data were presented here at the 34th annual meeting of the American Society of Clinical Oncology.

This study was designed to compare paclitaxel/carboplatin to cisplatin/etoposide. The trial enrolled 369 patients with advanced or metastatic NSCLC between May 1995 and July 1996. One hundred seventy-nine patients received cisplatin/etoposide and 190 received paclitaxel/carboplatin. After initial therapy, patients could receive additional chemotherapy.

"Survival in the control arm (cisplatin/etoposide) was unexpectedly higher, and this could be attributable to multiple factors, including second-line chemotherapy with a taxane-based regimen," said Chandra Belani, M.D., associate professor of medicine at the University of Pittsburgh School of Medicine and co-director of the Lung Cancer Program at the University of Pittsburgh Cancer Institute (UPCI).

"Patients in the paclitaxel arm of the study experienced a greater response rate compared to cisplatin/etoposide, 23 percent versus 14 percent respectively," explained Dr. Belani. "Patients who received paclitaxel/carboplatin experienced improvement in quality of life from baseline to third course of chemotherapy."

"In 1998 we are not only talking about first-line therapy NSCLC, but we now need to pursue second-line chemotherapy," concluded Dr. Belani.

The ongoing phase III studies with the paclitaxel/carboplatin regimen being performed by the SWOG, ECOG, CALGB will further substantiate the results of this regimen with NSCLC.

Lung cancer is one the most common cancers in the United States, representing about 15 percent of all cancer cases, or 178,000 new cases in 1997. Lung cancer accounts for over one-fourth (28 percent) of cancer deaths in the Un

Contact: Lauren Ward
University of Pittsburgh Medical Center

Page: 1 2

Related medicine news :

1. Indiana University researchers closer to helping hearing-impaired using stem cells
2. Boston University team finds link between high cholesterol and better cognitive performance
3. University seeks recruits for arthritis study
4. University of Manchester awarded 826k for brain science and mental health research
5. $4 million grant boosts University of Michigan campaign for a new childrens hospital
6. Lead in the environment causes violent crime, reports University of Pittsburgh researcher at AAAS
7. Next generation body scanner launched by the University of Manchester
8. University of Washington joins new Autism Treatment Network to provide better medical services
9. Binghamton University launches microelectronics research center
10. University of Manchester makes made-to-measure skin and bones a reality using inkjet printers
11. RelayHealth selected by Columbia University to link doctors and patients online

Post Your Comments:

(Date:5/30/2020)... ... 29, 2020 , ... Worldwide Business with kathy ireland® will be LIVE streaming ... Wednesday, June 3, 2020 at 8:00pm ET / PT – two chances to watch each ... Med , and Diagnostic Solutions Laboratory . , As leaders in ...
(Date:5/30/2020)... ... May 29, 2020 , ... In appreciation for all the ... ever, James Hodge Hyundai is offering a $500 bonus towards the lease or purchase ... incentive now through January 4, 2021. , To qualify for this offer, individuals must ...
(Date:5/28/2020)... (PRWEB) , ... May 28, 2020 , ... ... healthcare organization is joining the clinically integrated network (CIN) and the group purchasing ... with AHN’s Cardiovascular Institute to establish a heart failure program at Mon Health ...
(Date:5/28/2020)... , ... May 28, 2020 , ... ... fully re-open in the fall, operators of student housing are scrambling to implement ... COCM, which manages over 37,000 student housing beds on 38 campuses across the ...
(Date:5/27/2020)... ... 27, 2020 , ... The podiatrists and foot doctors of Advanced Foot & ... , and Ann Arbor Michigan. Dr. Tomasz Biernacki states that “Podiatrists can ... at the hospital. We have been seeing patients in the hospital for the past ...
Breaking Medicine News(10 mins):
(Date:5/28/2020)... ... May 28, 2020 , ... This new Notify.com ... is an acknowledgement-based notification platform,” said Bob Lueth, President of Notify.com. “This ... SMS text message, Email or Voice phone call—will be tracked by Notify.com, in ...
(Date:5/27/2020)... ... May 27, 2020 , ... NDA Partners Chairman Carl ... with more than 25 years of experience in product design, development, and manufacturing ... Consultant. His expertise includes quality assurance, including ISO 13485 and FDA QSR (21 ...
(Date:5/27/2020)... ... May 27, 2020 , ... Hemp Health One’s Giving Away Free CBD Supplements for the next ... 60 days. The company is hosting the daily giveaway contest on its Instagram and Facebook ... One’s Instagram page or Hemp Health One’s Facebook page. Then, like the most recent post, ...
Breaking Medicine Technology:
Cached News: