Untreated postmenopausal women with osteoporosis

BOSTON (April 28, 2004) Results of a new analysis found that, without treatment, one out of 13 postmenopausal osteoporotic women who were initially fracture-free were likely to experience a spinal fracture within one year. This risk of fracture was present despite these patients taking supplemental calcium, and if necessary, Vitamin D. Data were presented today at the annual meeting of the American Association of Clinical Endocrinologists (AACE).

Additionally, a statistical model was presented that predicted the progression over time of subsequent spinal fractures in a population of osteoporotic women who were initially fracture-free. The model was based upon data from the placebo arms of Phase III fracture trials for Actonel (risedronate sodium tablets), and it included data for 2,326 patients whose fracture status (i.e. number of spinal fractures) was assessed at baseline and at yearly intervals. The model showed that the prevalence of spinal fractures rapidly increased over time if the population of osteoporotic women was not treated, and projected that therapy which reduced the risk of a first fracture within one year could substantially reduce the risk of future fracture.

"We previously established in another analysis that a postmenopausal osteoporotic woman who has already suffered a spinal fracture has a one in five risk of having another spinal fracture within one year; therefore, intervening before that first fracture occurs is important," said Dr. Robert Lindsay, Chief of Internal Medicine at Helen Hayes Hospital, West Haverstraw, NY and principal investigator on this study. "With one in 13 osteoporotic women at risk of that first spinal fracture within the year, choosing a therapy proven to act rapidly is important."

About the Analysis
Data for the analysis were from patients in the placebo arms of the Actonel fracture trials (VERT-MN, VERT-NA, HIP). The women had lumbar spine or femoral neck bone mineral de


Page: 1 2 3 4

Related medicine news :

1. Growth hormone treatment improves symptoms of metabolic disorder in postmenopausal women
2. Many postmenopausal women with cardiovascular disease dont use lifesaving aspirin therapy
3. Abdominal fat indicates severity of metabolic syndrome in obese, postmenopausal women
4. Hormone therapy may still offer important health benefits to postmenopausal women
5. New research on reduced bone mass and risk of fracture in postmenopausal women
6. Research in monkeys suggests estrogen therapy may lower androgens in postmenopausal women
7. Estrogenlike drugs may eventually help postmenopausal women with weight gain
8. Estrogen offers no overall benefit for disease prevention in postmenopausal women with hysterectomy
9. Study finds fewer, but more advanced, colon cancers in postmenopausal women on E&P hormone therapy
10. Estrogren plus progestin decreases colorectal cancer in postmenopausal woman
11. New study details effects of exercise on sleep quality in postmenopausal women

Post Your Comments:

(Date:8/31/2020)... ... , ... Just found out your dear friend has cancer? , It’s hard to hear your ... shares their diagnosis. Once the shock wears off, the questions and fears can be overwhelming. ... best ways to help? Words are failing me. I’m scared. I want to DO something. ...
(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University Global (CSU ... affordable online education – is proud to announce its new master’s degree in ... its kind in the nation, the 60-credit hour program is designed to provide ...
(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to give back to ... 10 percent of each hotel room booked with a special new rate code to ... Indiana (RMHC-CNI) , effective immediately. Donations will be applied to any room type, ...
(Date:8/28/2020)... ... 28, 2020 , ... Ernst & Young LLP (EY US) ... Of The Year® 2020 Florida Award finalist. Now in its 34th year, the ... growth and prosperity as they build and sustain successful businesses that transform our ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Integrated ... Miami is the first Florida school to deploy its breakthrough Mobile Biodefense Indoor Air ... airborne COVID-19. True North Classical Academy plans to fully reopen equipped with the filtration ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... While coronavirus cases continue to increase across ... and community organizations remain closed. Because about 80% of blood donations are made at ... blood donors and blood drive hosts to ensure blood products are readily available for ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... If you live in New York City ... real estate part makes sense, it’s the law of supply and demand, but are plastic ... has a significant percentage of their patients that make the four-hour trip to have ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Dr. ... reproductive and endoscopic surgeon and serves as a clinical professor in the Department of ... of the American Laparoscopy Society & Pacific Coast Reproductive Society and is a Clinical ...
Breaking Medicine Technology:
Cached News: