A 2004 update to the National Cholesterol Education Program's (NCEP) clinical practice guidelines on cholesterol management advises physicians to consider new, more intensive treatment options for people at high and moderately high risk for a heart attack. These options include setting lower treatment goals for LDL ("bad") cholesterol and initiating cholesterol-lowering drug therapy at lower LDL thresholds.
The update,* published in the July 13 issue of Circulation: Journal of the American Heart Association, is endorsed by the National Heart, Lung, and Blood Institute (NHLBI), the American College of Cardiology, and the American Heart Association. The document is based on a review of 5 major clinical trials of statin therapy** conducted since the 2001 release of the NCEP's cholesterol guidelines known as the Adult Treatment Panel (ATP) III Report. NHLBI, a component of the National Institutes of Health, coordinates the NCEP.
"The recent trials add to the evidence that when it comes to LDL (bad) cholesterol, lower is better for persons with high risk for heart attack," said NHLBI Acting Director Barbara Alving, M.D. "These trials show a direct relationship between lower LDL cholesterol levels and reduced risk for major coronary events. So, it is important to consider more intensive treatment for people at very high risk," she added.
Major recommendations in the update include:
Contact: NHLBI Communications Office
NIH/National Heart, Lung, and Blood Institute 12-Jul-2004Page: 1 2 3 4 5 Related medicine news :1
. CDC: Update on current influenza season and vaccine supply in the United States2
. Updated adjuvant data presented at SABCS show 30 percent reduction in recurrence3
. Updated press release to October 2004 Cochrane Review4
. Update: Third International Conference on Cancer and the Adolescent5
. Updated data compares DOXIL (R)/CAELYX (TM) (doxorubicin HCl liposome injection) to Topotecan6
. Update on CDC outbreak investigation7
. Update on national asthma guidelines released8
. Newly Updated HIV Treatment Guidelines For Adults And Adolescents Available On The World Wide Web9
. Updated Results On Heart Assist Device Presented At International Transplant Meeting10
. Boston University team finds link between high cholesterol and better cognitive performance11
. Decreased levels of good cholesterol in children with Progeria may cause premature heart disease