HOME >> MEDICINE >> NEWS
Uric acid and heart disease

In this month's premier open access medical journal PLoS Medicine, John Danesh and colleagues from the University of Cambridge, along with investigators from the Icelandic Heart Association, report the single largest prospective study addressing the role of uric acid in heart disease.

The debate over the role of uric acid in heart disease has been going on for more than 50 years, starting with a paper published in 1951 which found higher serum uric acid concentrations in patients with coronary heart disease (CHD) compared with controls. Since then, measurement of serum uric acid has been suggested as a predictor of CHD. But many of the studies on serum uric acid are epidemiologic studies and have come to different conclusions about how useful measurement of uric acid is.

This study, along with a systematic review which combines their findings with those of 15 previously published prospective studies of serum uric acid - 9,458 cases of CHD and 155,084 controls in all - answers the question of the role of uric acid in prediction of CHD. Using all studies, they show that there is a very small role for uric acid in the prediction of disease but in the eight studies where all possible confounders had been removed this predictive role was lost.

What this paper does not do is directly address the question of whether or not serum uric acid is involved in causing CHD although it does suggest that serum uric acid levels are unlikely to be a major determinant of CHD. So although improving diet, losing weight, and controlling blood pressure may all contribute to reducing both one's risk of CHD and one's serum levels of uric acid, uric acid levels do not help to usefully predict the risk of CHD.


'"/>

Contact: Paul Ocampo
pocampo@plos.org
415-624-1224
Public Library of Science
28-Mar-2005


Page: 1

Related medicine news :

1. New study in Nature demonstrates protection against cell death during heart attack
2. Researchers search for first sign of congestive heart failure
3. Hopkins begins human trials with donor adult stem cells to repair muscle damaged from heart attack
4. Extreme exertion, emotion can spark repeat heart attacks
5. Men with severe sleep breathing disorder have higher risk of heart problems
6. Red wine protects the heart
7. Yale authors raise concerns regarding regionalized heart attack care
8. Community-based care beats standard clinic in lowering heart
9. Blacks less likely to get expensive, newer heart treatments
10. Vitamin E may not prevent cancer or cardiovascular events, but may increase risk for heart failure
11. Drug therapy may be comparable to invasive cardiac procedures for elderly patients with heart attack

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/21/2020)... (PRWEB) , ... May 21, 2020 , ... ... its award-winning population health management platform that supports care management and utilization management ... 100 individuals at client sites, TruCare 2020 provides significant usability and automation upgrades ...
(Date:5/21/2020)... ... May 21, 2020 , ... JNL Technologies Inc. , a manufacturer of ... the SafeHealth screening software. This tool allows companies to create an electronic ... the cost of additional paperwork management. , SafeHealth allows you to create a custom ...
(Date:5/16/2020)... MIAMI (PRWEB) , ... May 15, 2020 , ... For patients who have gone to ... control processes that the office has always had in place. After being allowed to re-open ... to ensure that patients and staff are as safe and comfortable as possible while going ...
(Date:5/16/2020)... ... May 15, 2020 , ... KUDO Inc., the leading Language-as-a-Service ... Medical Supplies (OSMS). The organization will obtain free access to the platform during ... COVID-19. , Created as a response to the COVID-19 pandemic in March 2020, ...
(Date:5/15/2020)... (PRWEB) , ... May 15, 2020 , ... COVID-19 has ... on their feet by making sure their employees can get back to work safely. ... they have expanded to gyms, restaurants, bars, and countless other settings. , Everyone needs ...
Breaking Medicine News(10 mins):
(Date:5/16/2020)... ... ... The private clinic, CLNQ has launched a coronavirus antibody test ... is manufactured by Abbott has been CE certified and previously had FDA approval. , ... blood testing kit to be sent their home. The sample is then sent ...
(Date:5/16/2020)... ... 2020 , ... Mold needs oxygen, moisture, warmth and food to grow. One ... Atascadero SERVPRO professionals advise that preventing water damage in the first place is ... and mold gives people more information to help control moisture and water damage that ...
(Date:5/15/2020)... ... 15, 2020 , ... AppleGate Recovery, a BayMark Health Services ... office-based opioid treatment (OBOT) program with two locations near New Orleans, LA. The ... in a physician’s office setting. , AppleGate Recovery now operates 8 clinics ...
Breaking Medicine Technology:
Cached News: