HOME >> MEDICINE >> NEWS
Use of statins may prevent breast cancer, say University of Pittsburgh researchers

PITTSBURGH, Oct. 16 Cholesterol-lowering medications may help to prevent breast cancer in older women, according to study findings published by University of Pittsburgh researchers in the October issue of the Journal of Women's Health.

"While scientists have known for years that cholesterol inhibition serves to inhibit tumor cell growth, our analysis is one of the first to look exclusively at the relationship between lipid-lowering medications and the development of breast cancer, and our findings are dramatically positive," said study author and lead investigator Jane Cauley, Dr.P.H., professor of epidemiology at the University of Pittsburgh Graduate School of Public Health.

The Pittsburgh-led study found that older women who took statins and non-statin lipid-lowering drugs experienced a 60 to 70 percent reduction in their risk of breast cancer over approximately seven years.

Researchers reviewed data on 7,528 white women age 65 years and older who participated in the Study of Osteoporotic Fractures at sites in Pittsburgh, Baltimore, Minneapolis and Portland, and followed them for seven years.

A total of 234 (3.3%) cases of breast cancer were reported among the 6,952 participants who reported no use of lipid-lowering drugs; six cases (2.1%) among the 284 women who used statins; and four cases (1.3%) among the 292 who used nonstatin lipid-lowering drugs. The combined group of lipid-lowering drug users had a 68 percent reduction in the risk of breast cancer.

Investigators adjusted for body mass index and other risk factors for breast cancer such as the age at menarche, age at first birth, parity, physical activity and alcohol consumption. The results were essentially the same in all cases.

"There is a significant difference in the percentage of breast cancer events between women who used lipid-lowering drugs and those who did not, and these findings have important public health implications given the widespread use
'"/>

Contact: Kathryn Duda
DudaK@upmc.edu
412-624-2607
University of Pittsburgh Medical Center
16-Oct-2003


Page: 1 2

Related medicine news :

1. Hepatotoxicity and statins
2. Jefferson scientists help explain statins effects in Alzheimers disease
3. Jefferson scientists uncover new evidence to help explain statins effects in Alzheimers disease
4. CRESTOR leads in 1st international prospective study of statins in the metabolic syndrome
5. OTC statins: A bad decision for public health
6. ESC highlights need for screening and global risk management as statins move over the counter in UK
7. ACP guidelines: Many diabetics should be taking statins
8. Patients should be allowed to pay for statins
9. Genetic bar codes predict effect of statins
10. Stopping statins may cause rebound that triples risk of death
11. Not enough evidence that multivitamins prevent infections in the elderly

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... ... March 24, 2017 , ... The iaedp Foundation, the premier provider of ... for those suffering from the full spectrum of disordered eating, announced today that the ... from nearly all 50 states and several countries converged on the Green Valley Resort ...
(Date:3/24/2017)... PA (PRWEB) , ... March 24, 2017 , ... ... Oncology Nursing Society (ONS) wanted to create a communications platform that positions them ... this goal, Elliance and ONS reinvented their online publication as an always-on, always-fresh ...
(Date:3/24/2017)... ... ... Viewers who like to educate themselves on current issues and who enjoy ... societal issues tend to appreciate and love the "Informed" series, hosted by Rob Lowe. ... for causes around the world. , Running for charity has become a ...
(Date:3/24/2017)... (PRWEB) , ... March 24, 2017 , ... ... How to Walk with God #TruthwithGrace”: a devotional journal chronicling the writer’s path ... to Learning How to Walk with God #TruthwithGrace” is the creation of published ...
(Date:3/24/2017)... ... ... “The Adventures of Joey, The Dog Who Barks at Puddles”: a boisterous story about ... as God intended. “The Adventures of Joey, The Dog Who Barks at Puddles” is ... for writing, especially about truth and human behavior. , Published by Christian Faith Publishing, ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... 23, 2017 The key factors driving ... diabetic population, accelerating economic growth and increasing healthcare expenditure. Some ... higher life expectancy of ESRD patients, rising demand for home ... the expansion of the market is hindered by high treatment ... ...
(Date:3/23/2017)... HICKORY, N.C. , March 23, 2017  Transportation ... accolades as an end-to-end supply chain management firm with ... of Consumer Product Solutions Rick Zaffarano was ... Star of the Supply Chain by the only publication ... the global food supply chain. "Rick has ...
(Date:3/23/2017)... and INDIANAPOLIS , March 23, 2017 ... ) and the William Sansum Diabetes Center have established ... people affected by diabetes through enhanced research, education and ... and cardiovascular disease bears a disproportionate weight on Latino ... said David Kerr , M.D., FRCPE, director of ...
Breaking Medicine Technology:
Cached News: