HOME >> MEDICINE >> NEWS
Vaccine against childhood pneumonia shows promise

A vaccine against pneumonia and invasive pneumococcal disease, a severe form of bacterial infection, can substantially reduce hospital admissions and improve the survival of children in developing countries, concludes a trial published in this week's issue of THE LANCET. The authors believe the vaccine should be made available to children in Africa, where rates of severe invasive pneumococcal disease are up to ten times higher than in industrialised countries.

Pneumonia causes an estimated 19% of the 10 million childhood deaths worldwide annually. The bacterium Streptococcus pneumoniae is responsible for up to half of all cases of severe childhood pneumonia in developing countries. It also causes serious bloodstream infections, meningitis, and otitis media (inflammation of the middle ear).

Felicity Cutts (Medical Research Council, UK and WHO) and colleagues recruited children aged 6-51 weeks in The Gambia from August 2000 to February 2003. Children were randomly assigned to receive either, three doses of diphtheria-tetanus-pertussis-Haemophilus influenzae serotype b vaccine as a control (8719), or three doses of this tetravalent vaccine mixed with a nine-valent pneumococcal conjugate vaccine (8718), with intervals of at least 25 days between doses. 333 of the 8189 children given the pneumococcal vaccine had an episode of pneumonia confirmed by chest x-ray compared with 513 of 8151 in the control group. The vaccine reduced the first episode of pneumonia diagnosed by chest x-ray by 37% and reduced admissions to hospital by 15%. Disease caused by the types of pneumococcus bacteria in the vaccine was lowered by 77% and overall child mortality by 16%. The vaccine also had a good safety profile.

Professor Cutts comments: "The trial results are highly promising, and provide us with a clearer picture of the pneumococcal disease burden in Africa. In the control group, 65% of invasive disease episodes were of serotypes contained in the nine-valent
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
24-Mar-2005


Page: 1 2

Related medicine news :

1. Vaccine may complement conventional treatment for chronic leukaemia
2. Vaccine preparedness, or not
3. Oct. 14 Web cast: Reporters Workshop -- Covering Vaccines & Immunizations
4. Vaccine reduces racial disparity in incidence of childhood pneumonia and meningitis
5. Vaccine nips breast cancer in the bud
6. Vaccine shows promise for kidney cancer
7. Vaccine development against influenza A (h5n1) virus should be made a priority
8. Vaccines against fatal African cattle fever
9. Vaccine development sparks debate on changes to cervical cancer screening guidelines
10. Vaccine shortage study exposes nations patchwork system
11. Vaccines prevent cancers of the liver and cervix

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/24/2019)... ... May 24, 2019 , ... NJ Top Docs is proud ... ever-changing, Dr. William F. Ziegler understands that staying abreast of new developments in reproductive ... experience, Dr. Ziegler doesn’t want to just treat patients; he wants to be a ...
(Date:5/23/2019)... ... May 23, 2019 , ... Spicy Lingerie, one of ... a special Memorial Day Weekend at SpicyLingerie.com . With discounts up to 80% ... one of the best on offer throughout the weekend. , Eighty percent discounts ...
(Date:5/23/2019)... ... May 23, 2019 , ... Hoban Law Group is proud to be ... Campaign. “It is essential to help educate the public about the most sweeping cannabis ... place to do so than Times Square,” said Hoban Law Group Founder & President ...
(Date:5/23/2019)... ... 23, 2019 , ... Join Dr. Ashok Srivastava, CEO & CMO at ClinFomatrix ... Sciences at OmniComm Systems, Inc. , in a live webinar on ... the benefits of visual patient profiles. Together, the two speakers bring years of experience ...
(Date:5/23/2019)... ... May 23, 2019 , ... Neurohacker Collective , ... with Emerson Ecologics. Qualia Mind, Qualia Focus, and Qualia Mind Caffeine Free are ... Emerson’s extensive nearly 40 year history of providing the broadest selection of wellness ...
Breaking Medicine News(10 mins):
(Date:5/23/2019)... (PRWEB) , ... May 23, 2019 , ... ... (MD QMS) software platform, is bringing their 2019 True Quality Roadshow, a ... June 13 at the Watson Block Event Center & Venue. , The ...
(Date:5/23/2019)... ... ... Moffitt Cancer Center and AdventHealth are working together to open an outpatient cancer ... “We strive to provide world-class cancer care close to where people live and work,” ... “Expanding Moffitt’s brand of oncology care, treatment and research in Pasco County helps us ...
(Date:5/23/2019)... ... ... NATIONAL OFFICE – BKD CPAs & Advisors is pleased to announce Danielle Solomon ... practice. Former NIP Eddie Marmouget will transition to a leadership role in Health Care ... care practice and work more closely with our team to innovate and provide solutions ...
Breaking Medicine Technology:
Cached News: