HOME >> MEDICINE >> NEWS
Vaccines against fatal African cattle fever

Research carried out in the Netherlands has led to the development of two new vaccines against East Coast Fever. This fatal cattle disease is prevalent in various parts of Africa and is caused by parasite transmitted by ticks. The new vaccines are easier to use and involve less risks than the current prevention measures.

During his doctoral research, Stephen Kaba made two vaccines based on a protein found on the surface of the parasite. In total, 72 percent of the animals that were injected with the new protein vaccines and subsequently infected with the parasite, were found to be protected. This protection was achieved with a low vaccine dosage and with just two injections. Previous protein vaccines could only protect half of the animals.

Up until now, veterinary surgeons have injected the entire parasite instead of one of its proteins. The cattle were also simultaneously treated with a cure of antibiotics. This method, which requires considerable skill and the culturing of large quantities of parasites, is a time-consuming and expensive process. An associated problem is that the parasites must be stored at a very low temperature, which is difficult in tropical areas. Furthermore, with this method there is always the chance that the animal could become ill as a result of the vaccination. The new vaccines do not have these problems.

The researchers developed two methods to make a stable form of the parasite protein, in large quantities in insect cells. They used modified baculovirusses for this. In one method the researchers linked the parasite protein to the carrier protein (Green Fluorescent Protein or GFP). In the other method the protein was attached to the outside of the baculovirus particles. Both products provided vaccines with a good level of effectiveness.

The protein used, p67, ensures that the parasite can penetrate white blood cells. The immune system of the cattle recognises this protein and makes antibodies against it
'"/>

Contact: Lydie van der Meer
news@nwo.nl
31-70-344-0713
Netherlands Organization for Scientific Research
11-Nov-2003


Page: 1 2

Related medicine news :

1. Oct. 14 Web cast: Reporters Workshop -- Covering Vaccines & Immunizations
2. Vaccines prevent cancers of the liver and cervix
3. T-Cell Memory Finding May Provide Key To Cancer, AIDS Vaccines
4. Study Injects New Interest In How Vaccines Work
5. Strategy effective against drug resistant tuberculosis
6. New study in Nature demonstrates protection against cell death during heart attack
7. Vaccine against childhood pneumonia shows promise
8. Mayo Clinic discovers new pathway against pancreatic cancer
9. Orthodontists must brace against back pain
10. NYUS Duster cautions against FDA approval of race-based pharmaceutical
11. Female sex hormones play a vital role in defense against sexually transmitted diseases

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/22/2017)... ... September 22, 2017 , ... Ecocor , ... Richard Pedranti Architect (RPA), a full-service architecture firm focusing on sustainable design, ... Line of Model Homes . Independently, Ecocor and RPA have extensive experience with ...
(Date:9/22/2017)... ... , ... Pullano Law Offices, a Chicago personal injury law firm, is pleased ... serve as President of the North Suburban Bar Association for 2017-2018. Mr. Pullano was ... the NSBA at the North Shore Country Club in Glenview, IL, on September 13, ...
(Date:9/22/2017)... Francisco, CA (PRWEB) , ... September 22, 2017 ... ... way to help you brush more effectively even on the go. Their electric ... like gingivitis and gum inflammation, with UV sanitizing technology. Combining leading edge Enke ...
(Date:9/22/2017)... (PRWEB) , ... September 22, 2017 , ... ... Lyme and other tick-borne diseases through research, education and awareness, today announced the ... A noted immunologist and microbiologist, Dr. Sellati has more than 20 years of ...
(Date:9/21/2017)... ... September 21, 2017 , ... The ... Behavioral Health Services for professionals in the addiction treatment industry entitled: Special ... , Insurance companies and state and federal governments are increasingly scrutinizing the ...
Breaking Medicine News(10 mins):
(Date:9/12/2017)... , Sept. 12, 2017  ValGenesis Inc., the ... (VLMS), is pleased to announce the appointment of ... of its Board of Directors and Chairman of ... enables life science companies to manage their entire ... of paper in this process. Furthermore, ValGenesis VLMS ...
(Date:9/7/2017)... Sept. 7, 2017  For nearly two decades, New Life Agency has ... Reproduction Insurance industry. Today, New Life Agency announces a powerful three-way partnership ... ... ... http://pharmacarecard.com/ (PRNewsfoto/PharmaCareCard) ...
(Date:9/6/2017)... -- Robert G. Szewc, M.D., is recognized by Continental Who,s ... his contributions to the Medical field.      ... practice of Kidney and Hypertension Specialists, which specializes in ... He has worked in this position since 2002, and ... as expertise in kidneys, hypertension, chronic disease and anemia, ...
Breaking Medicine Technology:
Cached News: