Vascular dementia patients taking ARICEPT show significant treatment benefits in cognition and function

ARICEPT efficacy and safety study in new treatment area presented at the Second International Congress on Vascular Dementia

Salzburg, Austria - Treatment with ARICEPT (donepezil hydrochloride tablets) significantly improved the cognitive and global (overall) function of patients with vascular dementia (VaD), compared with placebo, according to results from a first-of-its-kind clinical study presented today at the Second International Congress on Vascular Dementia (ICVD) in Salzburg, Austria. Only patients with VaD were included in this study. Patients with a diagnosis of Alzheimers disease (AD) were excluded. ARICEPT is currently indicated for the treatment of mild to moderate AD.

VaD, cognitive decline caused by a single, localized stroke, or series of strokes, is second only to AD as a cause of dementia. Up to one-third of all diagnosed dementia cases are VaD. In Europe, the prevalence of VaD is estimated to be 1.5 to 4.8 percent for people 70 to 80 years of age; of the patients over 65 years old diagnosed with dementia in the United States, approximately 9 to 39 percent have VaD.

This study is one of two conducted to examine the efficacy and safety of ARICEPT in patients with VaD, excluding patients diagnosed with AD. The results of the second study are expected to be released in mid 2002. Eisai, which discovered and developed ARICEPT, will work with its strategic alliance partner, Pfizer Inc., to file both studies with regulatory authorities worldwide for an indication to treat VaD.

"This groundbreaking study is the first time a cholinesterase inhibitor has been studied in a population composed primarily of patients with vascular dementia. VaD is a condition that has been underdiagnosed and undertreated," said Raymond D. Pratt, M.D., senior director, clinical research, Eisai Inc., who presented the data at the Second International Congress on Vascular Dementia. These results suggest ARICEPT may be a p

Contact: Melissa Furrie
Porter Novelli

Page: 1 2 3 4

Related medicine news :

1. Hebrew University one of 25 institutions involved in new European Vascular Genomics Network
2. No magic pill for treating dementia symptoms
3. Cardiovascular risk factors in midlife strongly linked to risk of dementia
4. Moderate alcohol intake may reduce risk of dementia in older women
5. Weight loss may be an early sign of dementia in the elderly
6. Reduced risk of institutionalisation in patients with dementia
7. Going through the motions to better treat dementia
8. Major overhaul needed in end-of life care for patients with dementia
9. Major overhaul needed in end-of life care for patients with dementia
10. Key immune system protein reduced in HIV-associated dementia patients
11. Researchers identify novel method of distinguishing Alzheimers disease from other types of dementia

Post Your Comments:

(Date:8/31/2020)... ... , ... Cardiothoracic surgeons at Allegheny General Hospital (AGH), part ... (CMU) to develop a new heart monitoring device designed to serve as an ... AGH/CMU team was recently awarded a “Trailblazer” grant from the National Institutes of ...
(Date:8/31/2020)... , ... August 31, 2020 , ... ... business management solution for chiropractors, announced today the launch of its integrated, HIPAA ... can start running their virtual practice in under 90 seconds. , According ...
(Date:8/31/2020)... ... , ... In an effort to give back to the community in which ... hotel room booked with a special new rate code to benefit children and families ... immediately. Donations will be applied to any room type, any time, now through ...
(Date:8/28/2020)... ... 28, 2020 , ... WHAT , Hespiro™ is a new ... conditions, including COVID-19, while reducing the need for scarce mechanical ventilators. It not ... and scrubs it free of carbon dioxide in a completely closed “rebreather” system, ...
(Date:8/28/2020)... ... 28, 2020 , ... A July 27 article ... at an increased risk of developing severe COVID-19 symptoms. The article does not ... the same organ systems that the coronavirus attacks are already suffering from the ...
Breaking Medicine News(10 mins):
(Date:9/2/2020)... ROCKWALL, Texas (PRWEB) , ... ... ... Preventative in the Fight Against Covid-19 , Advanced Penetration Technology, LLC, (APT) ... healthcare solutions for patients utilizing non-prescription, Over The Counter (OTC) products, was ...
(Date:9/1/2020)... ... September 01, 2020 , ... Agilent, a global leader ... Science and Technology Virtual Symposium 2020 (ASTVS 2020) on September 10-11, opening ... of Live webinars and Networking sessions, with a vast array of on-demand presentations ...
(Date:9/1/2020)... ... September 01, 2020 , ... Neil Oberfeld of global ... to the Board of Trustees and committee chair of the Governance Committee for ... Denver-based nonprofit organization that fights for the education, health, and financial stability of ...
Breaking Medicine Technology:
Cached News: