Viagra significantly effective, well-tolerated for men taking multiple blood pressure ...( sure for 11.7 years with 307 men takin...),Health

sure for 11.7 years, with 307 men taking two and 222 men taking three or more antihypertensive medications including, diuretics, beta-blockers, alpha-blockers, angiotensin converting enzyme inhibitors and calcium channel blockers. In addition, the men in the study experienced ED for an average of 4.5 years. Researchers measured the efficacy of Viagra by querying patients using the International Index of Erectile Function, two global efficacy assessment questions and the Erectile Dysfunction Inventory of Treatment Satisfaction, all standard measures.

Viagra is a prescription medication available only from doctors and should always be used in accordance with its approved labeling. Viagra is contraindicated in patients who use nitrates in any form at any time.

Viagra should be prescribed with caution in patients with recent serious cardiovascular events, strokes, or hypotension or uncontrolled hypertension or retinitis pigmentosa. Before treating ED, physicians should consider whether the mild and transient vasodilatory effects of Viagra on blood pressure could adversely affect patients with underlying cardiovascular disease or other more unusual conditions, especially in combination with the impact of resuming sexual activity.

When the alpha blocker doxazosin (4 mg) and Viagra (25 mg) were administered to patients with benign prostatic hyperplasia, mean additional reductions of supine blood pressure of 7 mm Hg systolic and 7 mm Hg diastolic were observed, and the combination of agents was well tolerated. When higher doses of Viagra and doxazosin (4 mg) were administered simultaneously, there were infrequent reports of patients who experienced symptomatic postural hypotension within 1 to 4 hours of dosing. Simultaneous administration of a PDE5 inhibitor to patients taking alpha-blocker therapy may lead to symptomatic hypotension in some patients.Patients on multiple antihypertensive medications were included in the clinical trials for Viag
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Contact: Geoff Cook
212-733-5244
Porter Novelli
15-May-2002

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